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Akademický článek

Adult neural stem cell fate is determined by thyroid hormone activation of mitochondrial metabolism

Autor: J.D. Gothié, A. Sébillot, C. Luongo, M. Legendre, C. Nguyen Van, K. Le Blay, M. Perret-Jeanneret, S. Remaud, B.A. Demeneix

Publikováno v: Molecular Metabolism, Vol 6, Iss 11, Pp 1551-1561 (2017)

Objective: In the adult brain, neural stem cells (NSCs) located in the subventricular zone (SVZ) produce both neuronal and glial cells. Thyroid hormones (THs) regulate adult NSC differentiation towards a neuronal phenotype, but also have major roles

Externí odkaz: https://doaj.org/article/53e29406b5db4a5db782672e147f8827

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Differential thyroid hormone sensitivity of fast cycling progenitors in the neurogenic niches of tadpoles and juvenile frogs

Autor: L, Préau, K, Le Blay, E, Saint Paul, G, Morvan-Dubois, B A, Demeneix

Publikováno v: Molecular and cellular endocrinology. 420

Adult neurogenesis occurs in neural stem cell (NSC) niches where slow cycling stem cells give rise to faster cycling progenitors. In the adult mouse NSC niche thyroid hormone, T3, and its receptor TRα act as a neurogenic switch promoting progenitor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::023728a57fc4b3178fae1b39d1996bdd
https://pubmed.ncbi.nlm.nih.gov/26628040

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Involvement of the membrane form of tumour necrosis factor‐&agr; in lipopolysaccharide‐induced priming of mouse peritoneal macrophages for enhanced nitric oxide response to lipopolysaccharide

Autor: J. F. Pons, R. Chaby, H. Fahmi, K. Le Blay, P. Ancuta

Publikováno v: Immunology. 92:259-266

We studied the pathways of macrophage response to lipopolysaccharide (LPS). When mouse macrophages pre-exposed to LPS were restimulated with this agent, reduced tumour necrosis factor-alpha (TNF-alpha) responses (desensitization/endotoxin tolerance)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e673a9113405277a399a85b2ae3ea5
https://doi.org/10.1046/j.1365-2567.1997.00338.x

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Characterisation of ovine Bordetella parapertussis isolates by analysis of specific endotoxin (lipopolysaccharide) epitopes, filamentous haemagglutinin production, cellular fatty acid composition and antibiotic sensitivity

Autor: Iver Heron, K. Le Blay, A. van Der Zee, K. Connor, P. Ibsen, J.F. Porter, F. Reubsaet, Richard Chaby, W. Donachie

Publikováno v: FEMS Microbiology Letters. 132:195-201

Isolates of Bordetella parapertussis, recovered from sheep or man, were characterised by reaction with specific anti-Bordetella lipopolysaccharide monoclonal antibodies, production of filamentous haemagglutinin, fatty acid patterns, and antibiotic se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7a3b9a95d3f7b33ce72518f0fde956
https://doi.org/10.1111/j.1574-6968.1995.tb07833.x

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Specific and cross-reacting monoclonal antibodies to Bordetella parapertussis and Bordetella bronchiseptica lipopolysaccharides

Autor: Richard Chaby, Martine Caroff, Malcolm B. Perry, K. Le Blay, James C. Richards

Publikováno v: Microbiology. 140:2459-2465

Three groups of monoclonal antibodies (mAbs) were produced that would be useful for immunochemical typing and diagnosis of infections due to Bordetella species, and for the structural analysis of their lipopolysaccharides. PP6, a representative of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1546ef33db868c0035bed722bb0ba03a
https://doi.org/10.1099/13500872-140-9-2459

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Akademický článek

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Chemical and serological characterization of the Bordetella hinzii lipopolysaccharides

Autor: L, Aussel, R, Chaby, K, Le Blay, J, Kelly, P, Thibault, M B, Perry, M, Caroff

Publikováno v: FEBS letters. 485(1)

Bordetella hinzii has recently been isolated from immunocompromised human hosts. The polysaccharides isolated from its endotoxin (lipopolysaccharide, LPS) were investigated using chemical analyses, NMR, gas-liquid chromatography/mass spectrometry and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6629dd9011d7c054839b1d5569cdb7fd
https://pubmed.ncbi.nlm.nih.gov/11086162

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Structural and functional consequences of amino acid substitutions in the second conserved loop of Escherichia coli adenylate kinase

Autor: Thierry Rose, Octavian Bârzu, W K Surewicz, Jochen Reinstein, Philippe Glaser, Anne-Marie Gilles, K Le Blay, H H Mantsch

Publikováno v: The Journal of Biological Chemistry
Europe PubMed Central

All known nucleoside monophosphate kinases contain an invariant sequence Asp-Gly-Phe(Tyr)-Pro-Arg. In order to understand better the structural and functional role of individual amino acid residues belonging to the above sequence, three mutants of Es

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf5cc9619d7f55ade388ef791040bfd
https://doi.org/10.1016/s0021-9258(18)54334-9

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Akademický článek

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Akademický článek

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