Výsledky vyhledávání - "K, Kronquist"

Akademický článek

High pulse pressure impairs cerebral artery endothelial function in young, but not old, mice

Autor: Nick R. Winder, Emily H. Reeve, Elise K. Kronquist, Aleena Khurana, Byron Lee, Thuan Nguyen, Grant D. Henson, Ashley E. Walker

Publikováno v: Experimental Gerontology, Vol 173, Iss , Pp 112101- (2023)

One of the hallmarks of vascular aging is increased pulse pressure. This elevated pulse pressure is associated with deleterious effects on cerebral vascular function; however, it is unknown if age modulates the susceptibility to high pulse pressure.

Externí odkaz: https://doaj.org/article/dbd1d2809b64437aa6065a59bc6d6a72

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Akademický článek

Elastin Insufficiency Confers Proximal and Distal Pulmonary Vasculopathy in Mice, Partially Remedied by the KATP Channel Opener Minoxidil: Considerations and Cautions for the Treatment of People With Williams-Beuren Syndrome

Autor: Russell H. Knutsen, Leah M. Gober, Elise K. Kronquist, Maninder Kaur, Danielle R. Donahue, Danielle Springer, Zu Xi Yu, Marcus Y. Chen, Yi-Ping Fu, Feri Choobdar, My-Le Nguyen, Sharon Osgood, Joy L. Freeman, Neelam Raja, Mark D. Levin, Beth A. Kozel

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 9 (2022)

BackgroundWilliams Beuren syndrome (WBS) is a recurrent microdeletion disorder that removes one copy of elastin (ELN), resulting in large artery vasculopathy. Early stenosis of the pulmonary vascular tree is common, but few data are available on long

Externí odkaz: https://doaj.org/article/c78ace6652984ae09c04d4d5b7428a7c

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Akademický článek

Airflow Obstruction in Adults with Williams Syndrome and Mice with Elastin Insufficiency

Autor: Elise K. Kronquist, Maninder Kaur, Leah M. Gober, Russell H. Knutsen, Yi-Ping Fu, Zu-Xi Yu, Danielle R. Donahue, Marcus Y. Chen, Sharon Osgood, Neelam Raja, Mark D. Levin, Amisha Barochia, Beth A. Kozel

Publikováno v: Diagnostics, Vol 12, Iss 6, p 1438 (2022)

Williams–Beuren syndrome (WS) results from the deletion of 25–27 coding genes, including elastin (ELN), on human chromosome 7q11.23. Elastin provides recoil to tissues; emphysema and chronic obstructive pulmonary disease have been linked to its d

Externí odkaz: https://doaj.org/article/22bc546de50a497e9af62410db397f9c

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Pyridoxamine treatment ameliorates large artery stiffening and cerebral artery endothelial dysfunction in old mice

Autor: Emily H Reeve, Elise K Kronquist, Julia R Wolf, Byron Lee, Aleena Khurana, Hanson Pham, Abigail E Cullen, Jessica A Peterson, Antonio Meza, R Colton Bramwell, Laura Villasana, Daniel R Machin, Grant D Henson, Ashley E Walker

Publikováno v: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Age-related increases in large artery stiffness are associated with cerebrovascular dysfunction and cognitive impairment. Pyridoxamine treatment prevents large artery stiffening with advancing age, but the effects of pyridoxamine treatment on the cer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb295de694382c1cbae5cb2a0f3cfe1
https://pubmed.ncbi.nlm.nih.gov/36189840

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Inhibition of NOX1 Mitigates Blood Pressure Increases in Elastin Insufficiency

Autor: Beth A. Kozel, Zu Xi Yu, Amanda Wardlaw-Pickett, Robert P. Mecham, Angela Troia, Elise K. Kronquist, Attila Kovacs, Kit Man Tsang, Russell H Knutsen, Carmen M. Halabi, Daniela Malide

Publikováno v: Function (Oxf)

Elastin (ELN) insufficiency leads to the cardiovascular hallmarks of the contiguous gene deletion disorder, Williams–Beuren syndrome, including hypertension and vascular stiffness. Previous studies showed that Williams–Beuren syndrome deletions,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::962bdb328a3f4776224293f523544bbd
https://doi.org/10.1093/function/zqab015

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Vascular Casting of Adult and Early Postnatal Mouse Lungs for Micro-CT Imaging

Autor: Elise K. Kronquist, Beth A. Kozel, Leah M. Gober, Joseph R. Sukinik, Danielle R. Donahue, Russell H Knutsen, Sean E. McLean, Mark D. Levin

Publikováno v: J Vis Exp

Blood vessels form intricate networks in 3-dimensional space. Consequently, it is difficult to visually appreciate how vascular networks interact and behave by observing the surface of a tissue. This method provides a means to visualize the complex 3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318a0b1a1a32c730014a03c4f06c6db5
https://doi.org/10.3791/61242

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Akademický článek

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Expression of myelin protein genes in the developing brain

Autor: A T, Campagnoni, B, Sorg, H J, Roth, K, Kronquist, S L, Newman, K, Kitamura, C, Campagnoni, B, Crandall

Publikováno v: Journal de physiologie. 82(4)

The major myelin proteins fall into two classes, the basic proteins and the proteolipid proteins. In mice, five forms of the myelin basic protein (MBP) have been identified with apparent molecular masses of 21.5 kD, 18.5 kD, 17 kD and 14 kD. The 17 k

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b4ced1f6625ec81ace9c917ca543a757
https://pubmed.ncbi.nlm.nih.gov/2460618

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