Zobrazeno 1 - 10
of 1 744
pro vyhledávání: '"K, Harvey"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Cerebral dopamine neurotrophic factor (CDNF) and its close structural relative, mesencephalic astrocyte-derived neurotrophic factor (MANF), are proteins with neurotrophic properties. CDNF protects and restores the function of dopamine (DA) n
Externí odkaz:
https://doaj.org/article/9bbc47d9ff964ed5a4326c26392a0c2d
Autor:
Diego Paine‐Cabrera, Lisa K. Harvey, Dakota R. Robarts, Michele T. Pritchard, John Thyfault, Steven A. Weinman, Udayan Apte, Voytek Slowik
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 12, Pp 2719-2728 (2023)
Abstract Non‐alcoholic fatty liver disease (NAFLD), newly renamed metabolic dysfunction‐associated liver disease (MASLD), is a leading cause of liver disease in children and adults. There is a paucity of data surrounding potential biomarkers and
Externí odkaz:
https://doaj.org/article/5f10513adf2048eea5c613c1608d2926
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-11 (2022)
Abstract Background Aberrations to endoplasmic/sarcoplasmic reticulum (ER/SR) calcium concentration can result in the departure of endogenous proteins in a phenomenon termed exodosis. Redistribution of the ER/SR proteome can have deleterious effects
Externí odkaz:
https://doaj.org/article/fd93747235684bd5a467c03348f87f42
Autor:
Maryna Koskela, T. Petteri Piepponen, Maria Lindahl, Brandon K. Harvey, Jaan-Olle Andressoo, Vootele Võikar, Mikko Airavaara
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-17 (2021)
Abstract Background Craving for alcohol, in other words powerful desire to drink after withdrawal, is an important contributor to the development and maintenance of alcoholism. Here, we studied the role of GDNF (glial cell line-derived neurotrophic f
Externí odkaz:
https://doaj.org/article/02e01585df47494e9bba26c02a845904
Autor:
Elliot J. Glotfelty, Luis B. Tovar-y-Romo, Shih-Chang Hsueh, David Tweedie, Yazhou Li, Brandon K. Harvey, Barry J. Hoffer, Tobias E. Karlsson, Lars Olson, Nigel H. Greig
Publikováno v:
Cells, Vol 12, Iss 10, p 1367 (2023)
Neuroinflammation is a unifying factor among all acute central nervous system (CNS) injuries and chronic neurodegenerative disorders. Here, we used immortalized microglial (IMG) cells and primary microglia (PMg) to understand the roles of the GTPase
Externí odkaz:
https://doaj.org/article/92ddbaddb19c409ea44ce0d43af5de5a
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
The lumen of the endoplasmic reticulum (ER) has resident proteins that are critical to perform the various tasks of the ER such as protein maturation and lipid metabolism. These ER resident proteins typically have a carboxy-terminal ER retention/retr
Externí odkaz:
https://doaj.org/article/055b9f5b3e3d4131b3297496d14b375d
Autor:
Reinis Svarcbahs, Sarah M. Blossom, Helena S. Baffoe-Bonnie, Kathleen A. Trychta, Lacey K. Greer, James Pickel, Mark J. Henderson, Brandon K. Harvey
Publikováno v:
Transgenic Research. 32:209-221
Maintenance of calcium homeostasis is important for proper endoplasmic reticulum (ER) function. When cellular stress conditions deplete the high concentration of calcium in the ER, ER-resident proteins are secreted into the extracellular space in a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dacd76a61397ae3f5d3d7c9b7ffc2836
https://doi.org/10.1007/s11248-023-00349-7
https://doi.org/10.1007/s11248-023-00349-7
Autor:
Jennifer M. Bossert, Carlos A. Mejias-Aponte, Thomas Saunders, Lindsay Altidor, Michael Emery, Ida Fredriksson, Ashley Batista, Sarah M. Claypool, Kiera E. Caldwell, David J. Reiner, Jonathan J. Chow, Matthew Foltz, Vivek Kumar, Audrey Seasholtz, Elizabeth Hughes, Wanda Filipiak, Brandon K. Harvey, Christopher T. Richie, Francois Vautier, Juan L. Gomez, Michael Michaelides, Brigitte L. Kieffer, Stanley J. Watson, Huda Akil, Yavin Shaham
Publikováno v:
The Journal of Neuroscience. 43:1692-1713
The brain µ-opioid receptor (MOR) is critical for the analgesic, rewarding, and addictive effects of opioid drugs. However, in rat models of opioid-related behaviors, the circuit mechanisms of MOR-expressing cells are less known because of a lack of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfe7ae4967be9d95039228d09b7a62b2
https://doi.org/10.1523/jneurosci.2049-22.2023
https://doi.org/10.1523/jneurosci.2049-22.2023
Autor:
Seong-Jin Yu, Kuo-Jen Wu, Eunkyung Bae, Yu –Syuan Wang, Chia-Wen Chiang, Li-Wei Kuo, Brandon K. Harvey, Nigel H. Greig, Yun Wang
Publikováno v:
iScience, Vol 23, Iss 2, Pp - (2020)
Summary: Acetylcholinesterase (AChE) inhibitors have protective and anti-inflammatory actions against brain injury, mediated by nicotinic α7 cholinergic receptor activation. The use of AChE inhibitors in patients is limited by systemic cholinergic s
Externí odkaz:
https://doaj.org/article/67c553801e72468aa34a8ae9732e025c