Zobrazeno 1 - 10
of 46
pro vyhledávání: '"K, Grundt"'
Publikováno v:
Acta Pharmacologica et Toxicologica. 51:6-11
The effect of methyl mercury (MeHg) and triethyllead (Et3Pb) on the membrane bound SH-enzymes Na+K+ATPase and pyruvate dehydrogenase (PDH) was studied in relation to the effect on the galactosyl ceramide sulfotransferase (CST) and to morphological ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abb32a45980232cc17f96ac31bd427cb
https://doi.org/10.1111/j.1600-0773.1982.tb01055.x
https://doi.org/10.1111/j.1600-0773.1982.tb01055.x
Autor:
I. K. Grundt, A. M. Bakken
Publikováno v:
Acta Pharmacologica et Toxicologica. 59:11-16
To obtain more information on the biochemical background, of methyl mercury (MeHg) and triethyl lead (Et3Pb) toxicity, the doses which were needed to alter the cellular content of adenine nucleotides were compared to doses which induced morphological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::821adb938b1ee09bb73ac0efc58c1532
https://doi.org/10.1111/j.1600-0773.1986.tb00128.x
https://doi.org/10.1111/j.1600-0773.1986.tb00128.x
Publikováno v:
Journal of Lipid Research, Vol 21, Iss 2, Pp 162-168 (1980)
Suckling rats were exposed to methylmercury chloride or diethylmercury in order to induce chronic sublethal intoxication during the period of active myelination. Doses of 5 mg Hg/kg body weight were injected every second day from 5-25 days of age. Th
Externí odkaz:
https://doaj.org/article/918e832f883248d5a6301c63175ffb12
Publikováno v:
Alternatives to Laboratory Animals. 25:289-296
The developing nervous system is vulnerable to heavy metal exposure, which can cause alterations in neuronal and glial cells in the brain. Thus, heavy metals such as mercury and lead reduce myelin galactocerebroside (GalC) synthesis, and increase the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9cee931c16b232c461fec8591961afd
https://doi.org/10.1177/026119299702500309
https://doi.org/10.1177/026119299702500309
Autor:
Harald Nyland, Inger K. Grundt
Publikováno v:
Alternatives to Laboratory Animals. 24:377-385
The reactions of a microglial cell population to exposure to interferon-gamma (IFN-γ) were studied in primary cultures of mixed glial cells from the brains of newborn rats. One week after seeding, the cells were exposed to 200U/ml of IFN-γ for 24 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb832c4f666c4b6b7445f7926a05f27b
https://doi.org/10.1177/026119299602400311
https://doi.org/10.1177/026119299602400311
Publikováno v:
Alternatives to Laboratory Animals. 23:513-520
— Several defence mechanisms against the toxicity of triethyllead (TEL) in cultures of glial cells have been studied. In contrast to cultures of glioma C6 cells, primary cultures of glial cells generated a resistance to the toxicity of TEL, which i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::473157b87c22782709db38a4d0172ee5
https://doi.org/10.1177/026119299502300415
https://doi.org/10.1177/026119299502300415
Autor:
Giancarlo Conti, Christian A. Vedeler, David E Pleasure, Inger K. Grundt, Roald Matre, Harald Nyland, Elling Ulvestad
Publikováno v:
Journal of Neuroimmunology. 49:19-24
Receptor for IgG (FcR) was demonstrated on rat microglia in vivo and in vitro by immunohistochemical staining with immune complexes of horseradish peroxidase (HRP) and rabbit IgG anti-HRP. Astrocytes, oligodendrocytes and neurons did not express FcR.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fcb5a5717f1c0fcfd5a119654c489f0
https://doi.org/10.1016/0165-5728(94)90176-7
https://doi.org/10.1016/0165-5728(94)90176-7
Publikováno v:
Alternatives to Laboratory Animals. 21:181-186
Factors which can have either an aggravating or a protective effect on glial cell activation, as found in the early stages of multiple sclerosis and other neurological disorders, are not well known. Enzyme analyses and time-lapse video film were used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6807985aa108c3d89cab10683d236577
https://doi.org/10.1177/026119299302100210
https://doi.org/10.1177/026119299302100210
Autor:
Harald Nyland, Inger K. Grundt
Publikováno v:
Alternatives to Laboratory Animals. 20:271-274
The toxicities of the therapeutic drugs amitriptyline and diazepam, the metal compounds methyl mercury and triethyllead, and the essential fatty acids linoleic acid and α-linolenic acid, were determined in a system of rat glial cells in culture with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6bb7d5b8c5cd51475b7c9a307ce941d
https://doi.org/10.1177/026119299202000217
https://doi.org/10.1177/026119299202000217
Publikováno v:
Alternatives to Laboratory Animals. 17:207-210
The effects of triethyllead on the morphology of brain macrophages have been studied in primary cultures of mixed glial cells from newborn rat brain. The cultures were exposed to the lead compound for two weeks at concentrations of 10-6, 10-7, 10-8 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d11da57d542c0ca15815a06d45bcd932
https://doi.org/10.1177/026119299001700315
https://doi.org/10.1177/026119299001700315