Zobrazeno 1 - 10
of 558
pro vyhledávání: '"K, Gough"'
Publikováno v:
Pilot and Feasibility Studies, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Introduction Prep-4-RT is a co-designed stepped-care multimodal prehabilitation program for people scheduled to receive radiotherapy for head and neck cancer (HNC). Prehabilitation, which occurs between diagnosis and treatment commencement,
Externí odkaz:
https://doaj.org/article/b72e565570664cea96cfb0831d21eb8f
Autor:
Ethan K. Gough, Thaddeus J. Edens, Lynnea Carr, Ruairi C. Robertson, Kuda Mutasa, Robert Ntozini, Bernard Chasekwa, Hyun Min Geum, Iman Baharmand, Sandeep K. Gill, Batsirai Mutasa, Mduduzi N.N. Mbuya, Florence D. Majo, Naume Tavengwa, Freddy Francis, Joice Tome, Ceri Evans, Margaret Kosek, Andrew J. Prendergast, Amee R. Manges
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105362- (2024)
Summary: Background: Small-quantity lipid-based nutrient supplements (SQ-LNS), which has been widely tested to reduce child stunting, has largely modest effects to date, but the mechanisms underlying these modest effects are unclear. Child stunting i
Externí odkaz:
https://doaj.org/article/9a74334eb4d940cf8c8fe200111a14c5
Autor:
Ceri Evans, Kuda Mutasa, Sandra Rukobo, Margaret Govha, Patience Mushayanembwa, Bernard Chasekwa, Florence D. Majo, Naume V. Tavengwa, Jonathan Broad, Christie Noble, Ethan K. Gough, Paul Kelly, Claire D. Bourke, Jean H. Humphrey, Robert Ntozini, Andrew J. Prendergast
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Children who are HIV-exposed but uninfected have increased infectious mortality compared to HIV-unexposed children, raising the possibility of immune abnormalities following exposure to maternal viraemia, immune dysfunction, and co-infection
Externí odkaz:
https://doaj.org/article/24a5828e11cb4ab6a03eddb2dabe2347
Autor:
Mary C. Boulanger, Margaret D. Krasne, Ethan K. Gough, Samantha Myers, Ilene S. Browner, Josephine L. Feliciano
Publikováno v:
Current Oncology, Vol 31, Iss 3, Pp 1389-1399 (2024)
Although cancer care is often contextualized in terms of survival, there are other important cancer care outcomes, such as quality of life and cost of care. The ASCO Value Framework assesses the value of cancer therapies not only in terms of survival
Externí odkaz:
https://doaj.org/article/99a00a868ab442a3b86c2e33537e7753
Autor:
Ruairi C. Robertson, Thaddeus J. Edens, Lynnea Carr, Kuda Mutasa, Ethan K. Gough, Ceri Evans, Hyun Min Geum, Iman Baharmand, Sandeep K. Gill, Robert Ntozini, Laura E. Smith, Bernard Chasekwa, Florence D. Majo, Naume V. Tavengwa, Batsirai Mutasa, Freddy Francis, Joice Tome, Rebecca J. Stoltzfus, Jean H. Humphrey, Andrew J. Prendergast, Amee R. Manges
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Here, using metagenomics, the authors show that the gut microbiome of rural Zimbabwean infants undergoes programmed maturation that is unresponsive to sanitation and nutrition interventions but is strongly associated with maternal HIV infection and c
Externí odkaz:
https://doaj.org/article/6e9a3dcb50674bc9b233dfce379b051b
Autor:
Ethan K. Gough
Publikováno v:
Infectious Diseases of Poverty, Vol 11, Iss 1, Pp 1-20 (2022)
Abstract Antibiotics have become a mainstay of healthcare in the past century due to their activity against pathogens. This manuscript reviews the impact of antibiotic use on the intestinal microbiota in the context of mass drug administration (MDA).
Externí odkaz:
https://doaj.org/article/5b242ca170e9431da14eb08497e4c59c
Autor:
James A Church, Sandra Rukobo, Margaret Govha, Ethan K Gough, Bernard Chasekwa, Benjamin Lee, Marya P Carmolli, Gordana Panic, Natasa Giallourou, Robert Ntozini, Kuda Mutasa, Monica M McNeal, Florence D. Majo, Naume V. Tavengwa, Jonathan R. Swann, Lawrence H Moulton, Beth D Kirkpatrick, Jean H Humphrey, Andrew J Prendergast
Publikováno v:
EClinicalMedicine, Vol 41, Iss , Pp 101173- (2021)
Background: Oral rotavirus vaccines (RVV) are poorly immunogenic in low-income countries. Environmental enteric dysfunction (EED) resulting from poor water, sanitation and hygiene (WASH) may contribute. We therefore tested associations between EED an
Externí odkaz:
https://doaj.org/article/69cb5ba48b6d461b9a9af23e66c7c284
Autor:
Catherine E. Simpson, Julie Coursen, Steven Hsu, Ethan K. Gough, Robert Harlan, Aurelie Roux, Susan Aja, David Graham, Matthew Kauffman, Karthik Suresh, Ryan J. Tedford, Todd M. Kolb, Stephen C. Mathai, Paul M. Hassoun, Rachel L. Damico
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L836-L848
In this cohort of patients with pulmonary arterial hypertension (PAH), we investigate metabolomic associations with comprehensive right ventricular (RV) functional measurements derived from multibeat RV pressure-volume loop analysis. Our results show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::004f8d2b6ed8aa02d9039f007895fe00
https://doi.org/10.1152/ajplung.00003.2023
https://doi.org/10.1152/ajplung.00003.2023
Autor:
Ethan K. Gough, Thaddeus J. Edens, Hyun Min Geum, Iman Baharmand, Sandeep K. Gill, Ruairi C. Robertson, Kuda Mutasa, Robert Ntozini, Laura E Smith, Bernard Chasekwa, Florence D. Majo, Naume V. Tavengwa, Batsirai Mutasa, Freddy Francis, Lynnea Carr, Joice Tome, Rebecca J. Stoltzfus, Lawrence H. Moulton, Andrew J. Prendergast, Jean H. Humphrey, Amee R. Manges, SHINE Trial Team
Publikováno v:
EBioMedicine, Vol 68, Iss , Pp 103421- (2021)
Background: Preterm birth and low birth weight (LBW) affect one in ten and one in seven livebirths, respectively, primarily in low-income and middle-income countries (LMIC) and are major predictors of poor child health outcomes. However, both have be
Externí odkaz:
https://doaj.org/article/66cbdb212225430e9f760331de1f448e
Publikováno v:
RMD Open, Vol 6, Iss 2 (2020)
This clinical case series describes our experience with the use of Janus kinase 1/2 inhibitor baricitinib in two patients suffering from refractory adult-onset Still’s disease (AOSD) as well as in one case suffering from AOSD-like autoinflammatory
Externí odkaz:
https://doaj.org/article/2c6af0472d784fe69198cae1d38e7860