Zobrazeno 1 - 10
of 105
pro vyhledávání: '"K, Engelbart"'
Autor:
Avirup Chakraborty, Changlin Yang, Jesse L. Kresak, Aryeh J. Silver, Diana Feier, Guimei Tian, Michael Andrews, Olusegun O. Sobanjo, Ethan D. Hodge, Mia K. Engelbart, Jianping Huang, Jeffrey K. Harrison, Matthew R. Sarkisian, Duane A. Mitchell, Loic P. Deleyrolle
Publikováno v:
Cells, Vol 13, Iss 11, p 938 (2024)
Glioblastoma (GBM) poses a significant challenge in clinical oncology due to its aggressive nature, heterogeneity, and resistance to therapies. Cancer stem cells (CSCs) play a critical role in GBM, particularly in treatment resistance and tumor relap
Externí odkaz:
https://doaj.org/article/da408b0d9d444c89803182abab76b701
Publikováno v:
Biochemical Journal. 275:469-476
The biochemical and morphological consequences of procollagen prolyl 4-hydroxylase inhibition by pyridine-2,4-dicarboxylic acid (2,4-PDCA) and its diethyl ester (diethyl-2,4-PDC) were studied in chick-embryo calvaria, which predominantly synthesize t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9179a6f1478b4428710e9322ce4b3228
https://doi.org/10.1042/bj2750469
https://doi.org/10.1042/bj2750469
Publikováno v:
Journal of Hepatology. 13:S26-S34
S 0885 and HOE 077 inhibit CCl 4 -induced liver fibrosis in rats, as shown by significantly reduced hydroxyproline content of the liver and improved liver histology. Mortality of drug-treated animals is significantly diminished. Serum collagen parame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff633f656d72497181d5cf1dbc06a66
https://doi.org/10.1016/0168-8278(91)90005-v
https://doi.org/10.1016/0168-8278(91)90005-v
Autor:
G, Horstmann, K, Engelbart
Publikováno v:
Arzneimittel-Forschung. 40(11)
Chronic intravenous toxicity studies in monkeys were carried out with 3-[(2,3-cyclopenteno-1-pyridinium)-methyl]-7-[2-syn-methoximino - 2-(2-aminothiazol-4-yl)-acetamido]-ceph-3-em-4-carboxylate (cefpirome, HR 810; CAS 84957-29-9) a new cephalosporin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4766c03246c048e1193ef0db66a94f20
https://pubmed.ncbi.nlm.nih.gov/1982210
https://pubmed.ncbi.nlm.nih.gov/1982210
Publikováno v:
Arzneimittel-Forschung. 40(9)
Subchronic and chronic toxicity studies in rats were performed with 3-[(2,3-Cyclopenteno-1-pyridinium)-methyl]- 7-[2-syn-methoximino-2-(2-aminothiazol-4-yl)-acetamido] -ceph-3-em-4- carboxylate (cefpirome, HR 810), a new cephalosporin derivative. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::70b4c977240d991fe72a947c4a3bff80
https://pubmed.ncbi.nlm.nih.gov/2080939
https://pubmed.ncbi.nlm.nih.gov/2080939
Publikováno v:
GnRH Analogues in Cancer and Human Reproduction ISBN: 9789401068116
Treatment of precocious puberty is a therapeutic problem with few satisfactory options. In boys, temporary suppression of androgen secretion is achieved by cyproterone acetate, but the results are not fully satisfactory because of adrenal steroid sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a48e2b531e93be02d6be26ffe6823242
https://doi.org/10.1007/978-94-009-0725-6_2
https://doi.org/10.1007/978-94-009-0725-6_2
Publikováno v:
Acta Endocrinologica. 94:489-497
Male pre-pubertal rats (60 g) were treated with the LRH analogue, [D-Ser(But)6]LRH(1—9)-nonapeptide-ethylamide (buserelin, Hoe 766), during 4 weeks by daily sc injections of 5, 50 or 500 ng peptide (group I, II and III). At the end of treatment, hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6f041c348810c4e5abafa3e2b1c810
https://doi.org/10.1530/acta.0.0940489
https://doi.org/10.1530/acta.0.0940489
Publikováno v:
Zeitschrift für Krebsforschung und Klinische Onkologie. 79:165-175
Es wird uber Abwandlungen an der Harnblasenschleimhaut von Wistar-Ratten und Beagle-Hunden in subchronischen und chronischen Toxicitatsversuchen mit einer 5-Nitrofuranverbindung berichtet. Die Verfutterung fuhrt dosisabhangig innerhalb weniger Wochen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6f18a8b50f465a255e6b420d04f3f45
https://doi.org/10.1007/bf00303675
https://doi.org/10.1007/bf00303675
Autor:
H. Kief, K. Engelbart
Publikováno v:
Virchows Archiv B Cell Pathology. 4:294-302
The quantitative changes induced by Glybenclamide in the content of both zinc and granules of the β-cells of Langerhans’ islets in rats are described. The insulin granules (stained with aldehyde thionine and pseudoisocyanine) decrease under acute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::caacd87507ec037cf13539ef32a85397
https://doi.org/10.1007/bf02906085
https://doi.org/10.1007/bf02906085
Publikováno v:
Zeitschrift f�r Krebsforschung. 67:57-68
Die Zellpopulationen von sieben Rattenfibroblastenstammen entwickelten nach einer etwa einjahrigen Phase der Instabilitat Chromosomenstammlinien, die entweder aneuploid oder pseudodiploid waren. Dabei tritt eine Vergroberung des Kernchromatins mit gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5a3816aba42afcdbfe683e2da081207
https://doi.org/10.1007/bf00524148
https://doi.org/10.1007/bf00524148