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Abstract Aging is associated a decrease in thirst sensation, which makes old people more susceptible to dehydration. Dehydration produces energy metabolism alterations. Our objective was to determinate the effect of water deprivation (WD) in the lipi

Externí odkaz: https://doaj.org/article/522d8088bc954ff7aba00694f1e31b64

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Akademický článek

Single-cell tumor-immune microenvironment of BRCA1/2 mutated high-grade serous ovarian cancer

Autor: I.-M. Launonen, N. Lyytikäinen, J. Casado, E. A. Anttila, A. Szabó, U.-M. Haltia, C. A. Jacobson, J. R. Lin, Z. Maliga, B. E. Howitt, K. C. Strickland, S. Santagata, K. Elias, A. D. D’Andrea, P. A. Konstantinopoulos, P. K. Sorger, A. Färkkilä

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

The tumour microenvironment has not been fully characterised in high-grade serous ovarian cancers (HGSOC). Here, the authors use highly multiplexed imaging to analyse the HGSOC immune microenvironment at spatial and single-cell resolution, with clini

Externí odkaz: https://doaj.org/article/3966d5c8320e4681ae12f840eb20d887

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Clinical Presentation of Patients with Pituitary Tumour and its Correlation to Magnetic Resonance Imaging: An Observational Study

Autor: Shaju Mathew, Geo Paul K Jose, Paruvakkattil Kunjan Balakrishnan, Ebitha K Elias

Publikováno v: International Journal of Anatomy Radiology and Surgery, Vol 10, Iss 04, Pp 11-14 (2021)

Introduction: Pituitary tumours are common intracranial tumours affecting mainly the 4th to 7th decade of life. A detailed understanding of these pituitary tumour patients, especially regarding their clinical and MRI profile would help in its earl

Externí odkaz: https://doaj.org/article/64aa0e4ec8b44f049bc8f667d1cabb58

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Akademický článek

Restricted feeding modulates peripheral clocks and nutrient sensing pathways in rats

Autor: Luis Guilherme F. Rodrigues, Leonardo D. de Araujo, Silvia L. R. Roa, Ana C. Bueno, Ernane T. Uchoa, José Antunes-Rodrigues, Ayrton C. Moreira, Lucila L. K. Elias, Margaret de Castro, Clarissa S. Martins

Publikováno v: Archives of Endocrinology and Metabolism, Vol 65, Iss 5, Pp 549-561 (2021)

ABSTRACT Objective: Feeding restriction in rats alters the oscillators in suprachiasmatic, paraventricular, and arcuate nuclei, hypothalamic areas involved in food intake. In the present study, using the same animals and experimental protocol, we aim

Externí odkaz: https://doaj.org/article/c73cb6b4c6684d72b2e62f2cfc4ddddf

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