Severity of coeliac disease and clinical management study when using a CYP3A4 metabolised medication: a phase I pharmacokinetic study

Autor: Marc L Chretien, David G Bailey, Linda Asher, Jeremy Parfitt, David Driman, Jamie Gregor, George K Dresser

Publikováno v: BMJ Open, Vol 10, Iss 3 (2020)

Objective Severity of coeliac disease depends in part on the extent of small intestinal mucosa injury. Patients with the most abnormal pathology have loss of duodenal villi CYP3A4, a drug-metabolising enzyme that inactivates many drugs. These patient

Externí odkaz: https://doaj.org/article/2ef254528b23423c8f711d116754b600

Hypertension Canada’s 2020 Comprehensive Guidelines for the Prevention, Diagnosis, Risk Assessment, and Treatment of Hypertension in Adults and Children

Autor: Robert A. Hegele, Peter Bolli, Milan Gupta, Steven A. Grover, Swapnil Hiremath, Andrew C. Don-Wauchope, Tabassum Firoz, Evelyne Rey, Simon W. Rabkin, Mike Sharma, Jonathan Y. Gabor, Fady Hannah-Shmouni, Charlotte Jones, Richard E. Gilbert, Janusz Kaczorowski, Vincent Woo, Janis M. Dionne, Alexander A. Leung, Sonia Butalia, Peter Selby, Tavis S. Campbell, Praveena Sivapalan, Ernesto L. Schiffrin, Andrew L. Pipe, André Michaud, Kevin C. Harris, Ruth Sapir-Pichhadze, Michael Roerecke, S. Brian Penner, Donna McLean, Luc Trudeau, Stella S. Daskalopoulou, Alexander G. Logan, Patrice Lindsay, Kim L. Lavoie, Meranda Nakhla, Anne Fournier, Alain Milot, Ellen Burgess, Gordon W. Moe, Jeffrey E. Alfonsi, Birinder K. Mangat, Alan Bell, Kelly B. Zarnke, Simon L. Bacon, Steven E. Gryn, Maxime Lamarre-Cliche, Ally P.H. Prebtani, Philip A. McFarlane, JoAnne Arcand, Nadia A. Khan, Ross T. Tsuyuki, Karen Tran, Michael D. Hill, Marcel Ruzicka, Jean Grégoire, François Audibert, George Honos, Michel Vallée, Kerry McBrien, Jesse Bittman, Laura A. Magee, Sheldon W. Tobe, Sandra M. Dumanski, Jonathan G. Howlett, Anne-Marie Côté, Ross D. Feldman, Geneviève Benoit, Doreen M. Rabi, Richard Lewanczuk, Kara Nerenberg, Laura M. Kuyper, Cedric Edwards, Lyne Cloutier, Raymond R. Townsend, Lawrence A. Leiter, George K. Dresser, Sofia B. Ahmed, Robert J. Herman, Alexandre Y Poppe, Ashkan Shoamanesh, Gregory L. Hundemer

Publikováno v: Canadian Journal of Cardiology. 36:596-624

Hypertension Canada's 2020 guidelines for the prevention, diagnosis, risk assessment, and treatment of hypertension in adults and children provide comprehensive, evidence-based guidance for health care professionals and patients. Hypertension Canada

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b24e7e0e9562ffd36f23a91f015af55
https://doi.org/10.1016/j.cjca.2020.02.086

Overcoming Challenges With Statin Therapy

Autor: J. David Spence, George K. Dresser

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 1 (2016)

Externí odkaz: https://doaj.org/article/8455d185811b4e2ab85e0e143c49abc0

Optimizing screening and management of cardiovascular health in prostate cancer

Autor: Chris A. Johnson, Jean Grégoire, Kim A. Connelly, Miran Kenk, Neil Fleshner, Margot K. Davis, Nina Ghosh, George K. Dresser, Shaun G. Goodman, Marc-Andre Coté

Publikováno v: Canadian Urological Association Journal. 14

In clinical practice, cancer management does not consistently encompass screening and identification of cardiovascular (CV) risk. The use of androgen deprivation therapy (ADT) in prostate cancer has been associated with increased CV risk and developm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f0bb6dded45b2dde7a402ace9bc6f956
https://doi.org/10.5489/cuaj.6685

Hypertension Canada’s 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children

Autor: Lyne Cloutier, G. V. Ramesh Prasad, George K. Dresser, Steven E. Gryn, Kara Nerenberg, Sonia Butalia, Alexander A. Leung, Andrew C. Don-Wauchope, Vincent Woo, Karen C. Tran, Simon L. Bacon, Laura M. Kuyper, Andrew L. Pipe, Marcel Ruzicka, George Honos, Milan Gupta, Janusz Feber, Richard Lewanczuk, Pavel Hamet, Gordon W. Moe, Kerry McBrien, Kevin C. Harris, Evelyne Rey, Theodore Wein, Mike Sharma, Donna McLean, Tavis S. Campbell, Ally P.H. Prebtani, Michael Roerecke, Robert A. Hegele, Peter Bolli, Janis M. Dionne, Swapnil Hiremath, Raj Padwal, Geneviève Benoit, Michel Vallée, Simon W. Rabkin, Guy Tremblay, Stella S. Daskalopoulou, S. Brian Penner, Sheldon W. Tobe, Thalia S. Field, Janusz Kaczorowski, Laura A. Magee, Ernesto L. Schiffrin, Meranda Nakhla, Charlotte Jones, Kaberi Dasgupta, Richard E. Gilbert, Anne-Marie Côté, JoAnne Arcand, Ross D. Feldman, Jean Grégoire, Tabassum Firoz, Alexander G. Logan, Michael D. Hill, Steven A. Grover, Alain Milot, Jonathan Y. Gabor, Peter Selby, Luc Trudeau, Philip A. McFarlane, Ellen Burgess, Patrice Lindsay, Maxime Lamarre-Cliche, Ross T. Tsuyuki, Praveena Sivapalan, Norman R.C. Campbell, Jonathan G. Howlett, Kim L. Lavoie, Anne Fournier, Doreen M. Rabi, Kelly B. Zarnke, Lawrence A. Leiter, Paul Oh, Cedric Edwards, Robert J. Herman, Raymond R. Townsend, Mark Gelfer, Gregory A. Kline, Ashkan Shoamanesh, Luc Poirier

Publikováno v: Nerenberg, K A, Zarnke, K B, Leung, A A, Dasgupta, K, Butalia, S, McBrien, K, Harris, K C, Nakhla, M, Cloutier, L, Gelfer, M, Lamarre-Cliche, M, Milot, A, Bolli, P, Tremblay, G, McLean, D, Padwal, R S, Tran, K C, Grover, S, Rabkin, S W, Moe, G W, Howlett, J G, Lindsay, P, Hill, M D, Sharma, M, Field, T, Wein, T H, Shoamanesh, A, Dresser, G K, Hamet, P, Herman, R J, Burgess, E, Gryn, S E, Grégoire, J C, Lewanczuk, R, Poirier, L, Campbell, T S, Feldman, R D, Lavoie, K L, Tsuyuki, R T, Honos, G, Prebtani, A P H, Kline, G, Schiffrin, E L, Don-Wauchope, A, Tobe, S W, Gilbert, R E, Leiter, L A, Jones, C, Woo, V, Hegele, R A, Selby, P, Pipe, A, McFarlane, P A, Oh, P, Gupta, M, Bacon, S L, Kaczorowski, J, Trudeau, L, Campbell, N RC, Hiremath, S, Roerecke, M, Arcand, J, Ruzicka, M, Prasad, G V R, Vallée, M, Edwards, C, Sivapalan, P, Penner, S B, Fournier, A, Benoit, G, Feber, J, Dionne, J, Magee, L A, Logan, A G, Côté, A-M, Rey, E, Firoz, T, Kuyper, L M, Gabor, J Y, Townsend, R R, Rabi, D M & Daskalopoulou, S S 2018, ' Hypertension Canada’s 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children ', Canadian Journal of Cardiology . https://doi.org/10.1016/j.cjca.2018.02.022

Hypertension Canada provides annually-updated, evidence-based guidelines for the diagnosis, assessment, prevention, and treatment of hypertension in adults and children. This year, the adult and pediatric guidelines are combined in one document. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfcc1108bc80632b46250a8df9f500cb
https://doi.org/10.1016/j.cjca.2018.02.022