Zobrazeno 1 - 10
of 1 486
pro vyhledávání: '"K, Daly"'
Publikováno v:
Frontiers in Environmental Science, Vol 12 (2024)
IntroductionOn intensive grassland dairy farms in high rainfall areas with poorly drained soils, networks of open drainage channels linked to in-field drainage systems are needed to enable farm operations. Nitrogen and phosphorus point and diffuse so
Externí odkaz:
https://doaj.org/article/975c6318a2e841778beb7a261f5b00ca
Autor:
Jane I. Grove, Camilla Stephens, M. Isabel Lucena, Raúl J. Andrade, Sabine Weber, Alexander Gerbes, Einar S. Bjornsson, Guido Stirnimann, Ann K. Daly, Matthias Hackl, Kseniya Khamina-Kotisch, Jose J. G. Marin, Maria J. Monte, Sara A. Paciga, Melanie Lingaya, Shiva S. Forootan, Christopher E. P. Goldring, Oliver Poetz, Rudolf Lombaard, Alexandra Stege, Helgi K. Bjorrnsson, Mercedes Robles-Diaz, Dingzhou Li, Thi Dong Binh Tran, Shashi K. Ramaiah, Sophia L. Samodelov, Gerd A. Kullak-Ublick, Guruprasad P. Aithal, on behalf of the TransBioLine consortium
Publikováno v:
Diagnostic and Prognostic Research, Vol 7, Iss 1, Pp 1-15 (2023)
Abstract A lack of biomarkers that detect drug-induced liver injury (DILI) accurately continues to hinder early- and late-stage drug development and remains a challenge in clinical practice. The Innovative Medicines Initiative’s TransBioLine consor
Externí odkaz:
https://doaj.org/article/01c9031ea63844faa64609c76d355eda
Publikováno v:
Frontiers in Environmental Science, Vol 12 (2024)
Introduction: On dairy farms with poorly drained soils and high rainfall, open ditches receive nutrients from different sources along different pathways which are delivered to surface water. Recently, open ditches were ranked in terms of their hydrol
Externí odkaz:
https://doaj.org/article/5b53f1d35d174ad7a7be25c617f2f39c
Autor:
Ann K. Daly
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 1, Pp 37-42 (2023)
Abstract Idiosyncratic drug‐induced liver injury (DILI) remains an important clinical problem, both during drug development and the prescription of a range of licensed drugs. Although rare, the consequences are serious. Ongoing studies on genetic r
Externí odkaz:
https://doaj.org/article/983f82f6462e4daab348d56b1ff02e72
Autor:
Danya Kabbani, Reem Akika, Ahmed Wahid, Ann K. Daly, Ingolf Cascorbi, Nathalie Khoueiry Zgheib
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Considerable efforts have been exerted to implement Pharmacogenomics (PGx), the study of interindividual variations in DNA sequence related to drug response, into routine clinical practice. In this article, we first briefly describe PGx and its role
Externí odkaz:
https://doaj.org/article/332e01f5704d4e678ab9fd59046233c8
Autor:
Laura K. Daly, Julian W.M. de Looze, David P. Forrestal, Michael Wagels, Ann-Louise Spurgin, Juliet D. Hoey, Michael R. Holt, Sarju Vasani, Mathilde R. Desselle
Publikováno v:
Annals of 3D Printed Medicine, Vol 9, Iss , Pp 100096- (2023)
A 78-year-old patient with a laryngectomy and a background of bronchiectasis experienced frequent hospital admissions due to pulmonary exacerbations. Standard care would be to trial a positive expiratory pressure (PEP) device to assist with secretion
Externí odkaz:
https://doaj.org/article/7cfb1691244a4264afefaefd95801d95
Autor:
Wei-Yu Lin, Sarah E. Fordham, Eric Hungate, Nicola J. Sunter, Claire Elstob, Yaobo Xu, Catherine Park, Anne Quante, Konstantin Strauch, Christian Gieger, Andrew Skol, Thahira Rahman, Lara Sucheston-Campbell, Junke Wang, Theresa Hahn, Alyssa I. Clay-Gilmour, Gail L. Jones, Helen J. Marr, Graham H. Jackson, Tobias Menne, Mathew Collin, Adam Ivey, Robert K. Hills, Alan K. Burnett, Nigel H. Russell, Jude Fitzgibbon, Richard A. Larson, Michelle M. Le Beau, Wendy Stock, Olaf Heidenreich, Abrar Alharbi, David J. Allsup, Richard S. Houlston, Jean Norden, Anne M. Dickinson, Elisabeth Douglas, Clare Lendrem, Ann K. Daly, Louise Palm, Kim Piechocki, Sally Jeffries, Martin Bornhäuser, Christoph Röllig, Heidi Altmann, Leo Ruhnke, Desiree Kunadt, Lisa Wagenführ, Heather J. Cordell, Rebecca Darlay, Mette K. Andersen, Maria C. Fontana, Giovanni Martinelli, Giovani Marconi, Miguel A. Sanz, José Cervera, Inés Gómez-Seguí, Thomas Cluzeau, Chimène Moreilhon, Sophie Raynaud, Heinz Sill, Maria Teresa Voso, Francesco Lo-Coco, Hervé Dombret, Meyling Cheok, Claude Preudhomme, Rosemary E. Gale, David Linch, Julia Gaal-Wesinger, Andras Masszi, Daniel Nowak, Wolf-Karsten Hofmann, Amanda Gilkes, Kimmo Porkka, Jelena D. Milosevic Feenstra, Robert Kralovics, David Grimwade, Manja Meggendorfer, Torsten Haferlach, Szilvia Krizsán, Csaba Bödör, Friedrich Stölzel, Kenan Onel, James M. Allan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Genome wide association studies in cancer are used to understand the heritable genetic contribution to disease risk. Here, the authors perform a genome wide association study in European patients with acute myeloid leukemia and identify loci associat
Externí odkaz:
https://doaj.org/article/b98174c0ab9448b282785b148dd6b082
Autor:
Partho Sen, Olivier Govaere, Tim Sinioja, Aidan McGlinchey, Dawei Geng, Vlad Ratziu, Elisabetta Bugianesi, Jörn M. Schattenberg, Antonio Vidal-Puig, Michael Allison, Simon Cockell, Ann K. Daly, Tuulia Hyötyläinen, Quentin M. Anstee, Matej Orešič
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104949- (2022)
Summary: Nonalcoholic fatty liver disease (NAFLD) is an increasingly prevalent disease that is associated with multiple metabolic disturbances, yet the metabolic pathways underlying its progression are poorly understood. Here, we studied metabolic pa
Externí odkaz:
https://doaj.org/article/ff48a05fd4c04ac5b4dbc6cdda589a9f
Autor:
Huma Shafique, Naeem Mahmood Ashraf, Amir Rashid, Asifa Majeed, Tayyaba Afsar, Ann K. Daly, Ali Almajwal, Nawaf W. Alruwaili, Azmat Ullah Khan, Suhail Razak
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Warfarin has been widely used as an oral anticoagulant agent. In past, efforts have been done to study the contribution of genetic variation on warfarin dose requirements. The possible therapeutic dose determination of warfarin is very challenging, i
Externí odkaz:
https://doaj.org/article/3572d466d3e14e53a46c24ef79035f19
Autor:
Aidan J. McGlinchey, Olivier Govaere, Dawei Geng, Vlad Ratziu, Michael Allison, Jerome Bousier, Salvatore Petta, Claudia de Oliviera, Elisabetta Bugianesi, Jörn M. Schattenberg, Ann K. Daly, Tuulia Hyötyläinen, Quentin M. Anstee, Matej Orešič
Publikováno v:
JHEP Reports, Vol 4, Iss 5, Pp 100477- (2022)
Background & Aims: Non-alcoholic fatty liver disease (NAFLD) is a progressive liver disease with potentially severe complications including cirrhosis and hepatocellular carcinoma. Previously, we have identified circulating lipid signatures associatin
Externí odkaz:
https://doaj.org/article/b18d61ce23654bedadb8ca0a30feb9ec