Zobrazeno 1 - 10
of 1 814
pro vyhledávání: '"K, Burgess"'
Autor:
Rosa K. Kortekaas, Kerstin E. Geillinger-Kästle, Rocío Fuentes-Mateos, Roël van Orsoy, Nakaa Al-Alyan, Janette K. Burgess, Reinoud Gosens
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionExacerbations of chronic obstructive pulmonary disease (COPD) increase mortality risk and can lead to accelerated loss of lung function. The increased inflammatory response during exacerbations contributes to worsening of airflow limitati
Externí odkaz:
https://doaj.org/article/f490fd823a3d4df79534252d7f20c695
Autor:
Mehmet Nizamoglu, Maunick Lefin Koloko Ngassie, Rhode A. Meuleman, Martin Banchero, Theo Borghuis, Wim Timens, Martijn C. Nawijn, Barbro N. Melgert, Irene H. Heijink, Corry-Anke Brandsma, Janette K. Burgess
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Abnormal deposition of extracellular matrix (ECM) in lung tissue is a characteristic of idiopathic pulmonary fibrosis (IPF). Increased collagen deposition is also accompanied by altered collagen organization. Collagen type XIV, a fibril-asso
Externí odkaz:
https://doaj.org/article/a8279a64c37149c6829e8aef79c36513
Autor:
Roderick H. J. de Hilster, Marjan A. Reinders-Luinge, Annemarie Schuil, Theo Borghuis, Martin C. Harmsen, Janette K. Burgess, Machteld N. Hylkema
Publikováno v:
Bioengineering, Vol 11, Iss 9, p 946 (2024)
Chronic obstructive pulmonary disease (COPD) is a chronic lung disease characterized by ongoing inflammation, impaired tissue repair, and aberrant interplay between airway epithelium and fibroblasts, resulting in an altered extracellular matrix (ECM)
Externí odkaz:
https://doaj.org/article/3df3b1d0ed8145518b10d63a49ca5e37
Autor:
Simon D. Pouwels, Alina Sigaeva, Shanna de Boer, Ilse A. Eichhorn, Lisanne Koll, Jeroen Kuipers, Romana Schirhagl, Irene H. Heijink, Janette K. Burgess, Dirk-Jan Slebos
Publikováno v:
Journal of Materials Science: Materials in Medicine, Vol 34, Iss 7, Pp 1-13 (2023)
Abstract Endoscopic implantation of medical devices for the treatment of lung diseases, including airway stents, unidirectional valves and coils, is readily used to treat central airway disease and emphysema. However, granulation and fibrotic tissue
Externí odkaz:
https://doaj.org/article/1ba4a7782bcb446bb0a4abb24a31640a
Publikováno v:
Materials Today Bio, Vol 23, Iss , Pp 100842- (2023)
This study aimed to investigate the impact of fibroblasts (MRC-5) on the extracellular matrix (ECM) microenvironment of endothelial cells (ECs) during the vascularization of skin-derived ECM hydrogel in vitro. Two types of ECs were studied: human der
Externí odkaz:
https://doaj.org/article/6b3deb400e7d474382bb547b99acc898
Autor:
Marissa Wisman, Mehmet Nizamoglu, Jacobien A. Noordhoek, Wim Timens, Janette K. Burgess, Irene H. Heijink
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
In idiopathic pulmonary fibrosis (IPF) constant epithelial micro-injury and aberrant interactions within the stromal micro-environment lead to abnormal alveolar repair and fibrosis. We hypothesized that alveolar epithelial regenerative responses in I
Externí odkaz:
https://doaj.org/article/cd370063ba214204a627d9caa69cbadd
Autor:
Mehmet Nizamoglu, Mugdha M. Joglekar, Catarina R. Almeida, Anna-Karin Larsson Callerfelt, Isabelle Dupin, Olivier T. Guenat, Pauline Henrot, Lisette van Os, Jorge Otero, Linda Elowsson, Ramon Farre, Janette K. Burgess
Publikováno v:
European Respiratory Review, Vol 32, Iss 169 (2023)
Chronic lung diseases result from alteration and/or destruction of lung tissue, inevitably causing decreased breathing capacity and quality of life for patients. While animal models have paved the way for our understanding of pathobiology and the dev
Externí odkaz:
https://doaj.org/article/45112fb21f5245cda99bbf5bf5e6e68e
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionAnalysis of respiratory biomarkers or pharmaceutical drug concentrations in bronchial epithelial lining fluid (bELF) using a high-precision sampling method is crucial for effective clinical respiratory diagnostics and research. Here, we u
Externí odkaz:
https://doaj.org/article/b8a85ba3a05048b4a7b5bf447659c254
Autor:
Rosa K. Kortekaas, Kerstin E. Geillinger-Kästle, Theo Borghuis, Kaoutar Belharch, Megan Webster, Wim Timens, Janette K. Burgess, Reinoud Gosens
Publikováno v:
ERJ Open Research, Vol 9, Iss 3 (2023)
Background Interleukin-11 (IL-11) is linked to the pathogenesis of idiopathic pulmonary fibrosis (IPF), since IL-11 induces myofibroblast differentiation and stimulates their excessive collagen deposition in the lung. In IPF there is disrupted alveol
Externí odkaz:
https://doaj.org/article/a8b885525ab44cb0b4fa31e6171fa9e5
Autor:
Mehmet Nizamoglu, Janette K. Burgess
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Disruption of the complex interplay between cells and extracellular matrix (ECM), the scaffold that provides support, biochemical and biomechanical cues, is emerging as a key element underlying lung diseases. We readily acknowledge that the lung is a
Externí odkaz:
https://doaj.org/article/5239dc59461e4f15837e93ad11af17f3