Zobrazeno 1 - 10
of 875
pro vyhledávání: '"K, Boyer"'
Autor:
Nancy Sue, Le May Thai, Atsushi Saito, Cierra K. Boyer, Ashleigh M. Fordham, Chenxu Yan, Aimee Davenport, Jiang Tao, Mohammed Bensellam, James Cantley, Yan-Chuan Shi, Samuel B. Stephens, Kazunori Imaizumi, Trevor J. Biden
Publikováno v:
Molecular Metabolism, Vol 79, Iss , Pp 101845- (2024)
Objective: Although individual steps have been characterized, there is little understanding of the overall process whereby glucose co-ordinates the biosynthesis of insulin with its export out of the endoplasmic reticulum (ER) and incorporation into i
Externí odkaz:
https://doaj.org/article/abf43cfa76f149028ed91ecd5b7f85a5
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract The pancreatic islet β-cell’s preference for release of newly synthesized insulin requires careful coordination of insulin exocytosis with sufficient insulin granule production to ensure that insulin stores exceed peripheral demands for g
Externí odkaz:
https://doaj.org/article/33b76294eda54b51bc2c9b04da020b7e
Autor:
Christie M. Penniman, Gourav Bhardwaj, Colette J. Nowers, Chandler U. Brown, Taylor L. Junck, Cierra K. Boyer, Jayashree Jena, Jordan D. Fuqua, Vitor A. Lira, Brian T. O'Neill
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 1, Pp 243-259 (2023)
Abstract Background Muscle mitochondrial decline is associated with aging‐related muscle weakness and insulin resistance. FoxO transcription factors are targets of insulin action and deletion of FoxOs improves mitochondrial function in diabetes. Ho
Externí odkaz:
https://doaj.org/article/c9f129a6962c4f9aa5ecf446caaba8e4
Autor:
Michelle H. Townsend, Zac E. Ence, Taylor P. Cox, John E. Lattin, Weston Burrup, Michael K. Boyer, Stephen R. Piccolo, Richard A. Robison, Kim L. O’Neill
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-15 (2020)
Abstract Background The aim of this study is to determine whether Hypoxanthine Guanine Phosphoribosyltransferase (HPRT) could be used as a biomarker for the diagnosis and treatment of B cell malignancies. With 4.3% of all new cancers diagnosed as Non
Externí odkaz:
https://doaj.org/article/67a3eff2e7cf4eb580f334fd9da89878
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 335 (2022)
Pancreatic islet β-cells exhibit tremendous plasticity for secretory adaptations that coordinate insulin production and release with nutritional demands. This essential feature of the β-cell can allow for compensatory changes that increase secretor
Externí odkaz:
https://doaj.org/article/a80f3bcbd8324d9cadb0474fb8129f28
Autor:
Christie M. Penniman, Gourav Bhardwaj, Colette J. Nowers, Chandler U. Brown, Taylor L. Junck, Cierra K. Boyer, Jayashree Jena, Jordan D. Fuqua, Vitor A. Lira, Brian T. O'Neill
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle. 14:243-259
Muscle mitochondrial decline is associated with aging-related muscle weakness and insulin resistance. FoxO transcription factors are targets of insulin action and deletion of FoxOs improves mitochondrial function in diabetes. However, disruptions in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e87a94a920031a61d758783168abcd6f
https://doi.org/10.1002/jcsm.13124
https://doi.org/10.1002/jcsm.13124
Autor:
Y Zhou, K Leahy, A Grose, J Lykins, M Siddiqui, N. Leong, P Goodall, S Withers, K Ashi, S Schrantz, V Tesic, A P Abeleda, K Beavis, F Clouser, M Ismail, M Christmas, R Piarroux, D Limonne, E Chapey, S Abraham, I Baird, J Thibodeau, K Boyer, E Torres, S Conrey, K Wang, MA Staat, N Back, J Gomez Marin, F Peyron, S Houze, M Wallon, R McLeod
Publikováno v:
medRxiv
BackgroundCongenital toxoplasmosis is a treatable, preventable disease, but untreated causes death, prematurity, loss of sight, cognition and motor function, and substantial costs worldwide.Methods/FindingsIn our ongoing USA feasibility/efficacy clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::176792bafbc1573849fed6ee42d849b2
https://europepmc.org/articles/PMC10168490/
https://europepmc.org/articles/PMC10168490/
Akademický článek
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Autor:
Shadrack J. Barnabas, Timo Böhme, Stephen K. Boyer, Matthias Irmer, Christoph Ruttkies, Ian Wetherbee, Todor Kondić, Emma L. Schymanski, Lutz Weber
Publikováno v:
Digital Discovery. 1:490-501
Extracting PFAS with open source cheminformatics toolkits reveals ~1.78 million PFAS in Google Patents, ~28 K in the CORE literature repository. The extraction of chemical information from documents is a demanding task in cheminformatics due to the v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7a960a333343757154598731b90e1e
https://doi.org/10.1039/d2dd00019a
https://doi.org/10.1039/d2dd00019a
Autor:
PE Campos, O Pruvost, K Boyer, F Chiroleu, TT Cao, M Gaudeul, C Baider, TMA Utteridge, S Dominick, N Becker, A Rieux, L Gagnevin
Over the past decade, the field of ancient genomics has triggered considerable progress in the study of various pathogens, including those affecting crops. In this context, herbarium collections have been an important source of dated, identified and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f4bed8f9881d0b36f24d199c29cc989
https://doi.org/10.1101/2022.12.08.519547
https://doi.org/10.1101/2022.12.08.519547