Zobrazeno 1 - 10
of 71
pro vyhledávání: '"K, Boregowda"'
Autor:
Walid Abushahba, Oyenike O Olabisi, Byeong-Seon Jeong, Rajeev K Boregowda, Yu Wen, Fang Liu, James S Goydos, Ahmed Lasfar, Karine A Cohen-Solal
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47312 (2012)
Riluzole, an inhibitor of glutamate release, has shown the ability to inhibit melanoma cell xenograft growth. A phase 0 clinical trial of riluzole as a single agent in patients with melanoma resulted in involution of tumors associated with inhibition
Externí odkaz:
https://doaj.org/article/cfe5d857e50a426298a1001d1dd687c4
Autor:
Venatrao Nunna, Karuna Kumar Mortha, Anil Thomas, Rajeev K. Boregowda, Shib D. Banerjee, Srinivasa Prasad Kolapalli
Publikováno v:
Cell Biochemistry and Function. 34:217-225
UNLABELLED Tumour cells generate hyaluronan (HA) oligomers (O-HA) by an autocrine mechanism to regulate their own behaviour through receptor interaction, necessitating analysis of HA sizes and its receptor expression in tumour progression. In this st
Autor:
Walid Abushahba, Wenjin Chen, Rajeev K. Boregowda, Oyenike O. Olabisi, Ahmed Lasfar, Marina Chekmareva, Byeong-Seon Jeong, Keneshia K. Haenssen, James S. Goydos, Karine A. Cohen-Solal, David J. Foran
Publikováno v:
Cancer Letters. 348:61-70
In the present study, we investigated the role of the transcription factor RUNX2 in melanomagenesis. We demonstrated that the expression of transcriptionally active RUNX2 was increased in melanoma cell lines as compared with human melanocytes. Using
Akademický článek
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Publikováno v:
Molecular and Cellular Biochemistry. 369:205-216
Integrins are transmembrane receptors that can specifically bind extracellular matrix (ECM) proteins. Assembly of the ECM protein fibronectin into fibrils has been shown to be a cell-mediated process that requires integrins. Like fibronectin, fibrill
Publikováno v:
Journal of Virology. 85:7754-7765
Initiation of reverse transcription in hepadnaviruses is accomplished by a unique protein-priming mechanism whereby a specific Y residue in the terminal protein (TP) domain of the viral reverse transcriptase (RT) acts as a primer to initiate DNA synt
Publikováno v:
Matrix Biology. 27:661-666
Fibrillins 1, 2 and 3 make up a family of genes that encode large, cysteine-rich extracellular matrix glycoproteins found in connective tissues, lung, blood vessels and other extensible tissues. Fibrillins 1 and 2 have both overlapping as well as sep
Autor:
Srinivasa Prasad, Kolapalli, Venatrao, Nunna, Anil, Thomas, Karuna Kumar, Mortha, Shib Das, Banerjee, Rajeev K, Boregowda
Publikováno v:
Cell biochemistry and function. 34(4)
Tumour cells generate hyaluronan (HA) oligomers (O-HA) by an autocrine mechanism to regulate their own behaviour through receptor interaction, necessitating analysis of HA sizes and its receptor expression in tumour progression. In this study for the
Autor:
Anna Rabkin, Marina Chekmareva, Samuel I. Gunderson, Suzie Chen, David J. Foran, Wenjin Chen, Rajeev K. Boregowda, Michael A. Bryan, Ahmed Lasfar, Daniel J. Medina, James S. Goydos, Karine A. Cohen-Solal, Michael J. Vido, Elke Markert
Publikováno v:
Oncotarget
Receptor tyrosine kinases-based autocrine loops largely contribute to activate the MAPK and PI3K/AKT pathways in melanoma. However, the molecular mechanisms involved in generating these autocrine loops are still largely unknown. In the present study,
Publikováno v:
Glycobiology. 15:1349-1358
We have cloned two GalNAc-4-sulfotransferases, GalNAc-4-ST1 and GalNAc-4-ST2, that transfer sulfate to terminal beta1,4-linked GalNAc. In conjunction with the action of protein-specific beta1,4GalNAc-transferases, GalNAc-4-ST1 and GalNAc-4-ST2 accoun