Zobrazeno 1 - 10
of 343
pro vyhledávání: '"K, Beier"'
Autor:
Pia V. Hönscheid, Gustavo B. Baretton, Martin Puhr, Tiziana Siciliano, Justus S. Israel, Matthias B. Stope, Celina Ebersbach, Alicia-Marie K. Beier, Christian Thomas, Holger H. H. Erb
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9275 (2024)
Cancer-associated fibroblast (CAF)s in the tumour microenvironment (TME) modulate the extracellular matrix, interact with cancer cells, and facilitate communication with infiltrating leukocytes, significantly contributing to cancer progression and th
Externí odkaz:
https://doaj.org/article/2416ac6cd99c47c9b6b00a8fede8a3a7
Autor:
Tiziana Siciliano, Ulrich Sommer, Alicia-Marie K. Beier, Matthias B. Stope, Angelika Borkowetz, Christian Thomas, Holger H. H. Erb
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 2, Pp 597-608 (2022)
The androgen receptor (AR) plays a central role in prostate, muscle, bone and adipose tissue. Moreover, dysregulated AR activity is a driving force in prostate cancer (PCa) initiation and progression. Consequently, antagonizing AR signalling cascades
Externí odkaz:
https://doaj.org/article/5eaa04aaad0f464fbc66e7cdf5778420
Autor:
Ulrich Sommer, Celina Ebersbach, Alicia-Marie K. Beier, Gustavo B. Baretton, Christian Thomas, Angelika Borkowetz, Holger H. H. Erb
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Immune checkpoint inhibitors have become a promising new therapy for cancer treatment. However, due to prostate cancer’s high heterogeneity and immune-suppressive tumour microenvironment, clinical trials with immune checkpoint inhibitors for prosta
Externí odkaz:
https://doaj.org/article/1772f66307de4de6821c29ea8328f328
Autor:
Celina Ebersbach, Alicia-Marie K. Beier, Pia Hönscheid, Christian Sperling, Korinna Jöhrens, Gustavo B. Baretton, Christian Thomas, Ulrich Sommer, Angelika Borkowetz, Holger H. H. Erb
Publikováno v:
Life, Vol 12, Iss 2, p 240 (2022)
Signal Transducer and Activator of Transcription (STAT) proteins have been identified as drivers of prostate cancer (PCa) progression and development of aggressive castration-resistant phenotypes. In particular, STAT3, 5, and 6 have been linked to re
Externí odkaz:
https://doaj.org/article/881d12c967dc484f93f7a32fe6c22fb7
Autor:
Ulrich Sommer, Tiziana Siciliano, Celina Ebersbach, Alicia-Marie K. Beier, Matthias B. Stope, Korinna Jöhrens, Gustavo B. Baretton, Angelika Borkowetz, Christian Thomas, Holger H. H. Erb
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1046 (2022)
Prostate-specific membrane antigen (PSMA) is an essential molecular regulator of prostate cancer (PCa) progression coded by the FOLH1 gene. The PSMA protein has become an important factor in metastatic PCa diagnosis and radioligand therapy. However,
Externí odkaz:
https://doaj.org/article/a3ea992a1d2c4aa5857b59ab36019b72
Publikováno v:
Zeitschrift für Ethik und Moralphilosophie. 6:1-3
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 149:2259-2270
Metabolic reprogramming has been recognised as a hallmark in solid tumours. Malignant modification of the tumour’s bioenergetics provides energy for tumour growth and progression. Otto Warburg first reported these metabolic and biochemical changes
Autor:
Tiziana Siciliano, Ingo H. Simons, Alicia-Marie K. Beier, Celina Ebersbach, Cem Aksoy, Robert I. Seed, Matthias B. Stope, Christian Thomas, Holger H. H. Erb
Publikováno v:
Life, Vol 11, Iss 9, p 874 (2021)
Antiandrogen therapy is a primary treatment for patients with metastasized prostate cancer. Whilst the biologic mechanisms of antiandrogens have been extensively studied, the operating protocols used for the characterization of these drugs were not i
Externí odkaz:
https://doaj.org/article/e902267dbb894c319cdca774d38c24e1
Publikováno v:
Zeitschrift für Ethik und Moralphilosophie. 5:99-101
Autor:
Robert Seed, Holger H.H. Erb, Celina Ebersbach, Tiziana Siciliano, Cem Aksoy, Christian Thomas, Alicia-Marie K. Beier, Matthias B Stope, Ingo H. Simons
Publikováno v:
Life
Volume 11
Issue 9
Life, Vol 11, Iss 874, p 874 (2021)
Volume 11
Issue 9
Life, Vol 11, Iss 874, p 874 (2021)
Antiandrogen therapy is a primary treatment for patients with metastasized prostate cancer. Whilst the biologic mechanisms of antiandrogens have been extensively studied, the operating protocols used for the characterization of these drugs were not i