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Refined cut-off for TP53 immunohistochemistry improves prediction of TP53 mutation status in ovarian mucinous tumors: implications for outcome analyses

Autor: Eun Young Kang, Dane Cheasley, Cecile LePage, Matthew J. Wakefield, Michelle da Cunha Torres, Simone Rowley, Carolina Salazar, Zhongyue Xing, Prue Allan, David D.L. Bowtell, Anne-Marie Mes-Masson, Diane M. Provencher, Kurosh Rahimi, Linda E. Kelemen, Peter A. Fasching, Jennifer A. Doherty, Marc T. Goodman, Ellen L. Goode, Suha Deen, Paul D.P. Pharoah, James D. Brenton, Weiva Sieh, Constantina Mateoiu, Karin Sundfeldt, Linda S. Cook, Nhu D. Le, Michael S. Anglesio, C. Blake Gilks, David G. Huntsman, Catherine J. Kennedy, Nadia Traficante, D. Bowtell, G. Chenevix-Trench, A. Green, P. Webb, A. DeFazio, D. Gertig, N. Traficante, S. Fereday, S. Moore, J. Hung, K. Harrap, T. Sadkowsky, N. Pandeya, M. Malt, A. Mellon, R. Robertson, T. Vanden Bergh, M. Jones, P. Mackenzie, J. Maidens, K. Nattress, Y.E. Chiew, A. Stenlake, H. Sullivan, B. Alexander, P. Ashover, S. Brown, T. Corrish, L. Green, L. Jackman, K. Ferguson, K. Martin, A. Martyn, B. Ranieri, J. White, V. Jayde, P. Mamers, L. Bowes, L. Galletta, D. Giles, J. Hendley, K. Alsop, T. Schmidt, H. Shirley, C. Ball, C. Young, S. Viduka, Hoa Tran, Sanela Bilic, Lydia Glavinas, Julia Brooks, R. Stuart-Harris, F. Kirsten, J. Rutovitz, P. Clingan, A. Glasgow, A. Proietto, S. Braye, G. Otton, J. Shannon, T. Bonaventura, J. Stewart, S. Begbie, M. Friedlander, D. Bell, S. Baron-Hay, A. Ferrier, G. Gard, D. Nevell, N. Pavlakis, S. Valmadre, B. Young, C. Camaris, R. Crouch, L. Edwards, N. Hacker, D. Marsden, G. Robertson, P. Beale, J. Beith, J. Carter, C. Dalrymple, R. Houghton, P. Russell, M. Links, J. Grygiel, J. Hill, A. Brand, K. Byth, R. Jaworski, P. Harnett, R. Sharma, G. Wain, B. Ward, D. Papadimos, A. Crandon, M. Cummings, K. Horwood, A. Obermair, L. Perrin, D. Wyld, J. Nicklin, M. Davy, M.K. Oehler, C. Hall, T. Dodd, T. Healy, K. Pittman, D. Henderson, J. Miller, J. Pierdes, P. Blomfield, D. Challis, R. McIntosh, A. Parker, B. Brown, R. Rome, D. Allen, P. Grant, S. Hyde, R. Laurie, M. Robbie, D. Healy, T. Jobling, T. Manolitsas, J. McNealage, P. Rogers, B. Susil, E. Sumithran, I. Simpson, K. Phillips, D. Rischin, S. Fox, D. Johnson, S. Lade, M. Loughrey, N. O'Callaghan, W. Murray, P. Waring, V. Billson, J. Pyman, D. Neesham, M. Quinn, C. Underhill, R. Bell, L.F. Ng, R. Blum, V. Ganju, I. Hammond, Y. Leung, A. McCartney, M. Buck, I. Haviv, D. Purdie, D. Whiteman, N. Zeps, Anna DeFazio, Scott Kaufmann, Michael Churchman, Charlie Gourley, Andrew N. Stephens, Nicola S. Meagher, Susan J. Ramus, Yoland C. Antill, Ian Campbell, Clare L. Scott, Martin Köbel, Kylie L. Gorringe, Georgina L. Ryland, Prue E. Allan, Kathryn Alsop, Sumitra Ananda, George Au-Yeung, Maret Böhm, Alison Brand, Georgia Chenevix-Trench, Michael Christie, Yoke-Eng Chiew, Rhiannon Dudley, Nicole Fairweather, Sian Fereday, Stephen B. Fox, Neville F. Hacker, Alison M. Hadley, Joy Hendley, Gwo-Yaw Ho, Sally M. Hunter, Tom W. Jobling, Kimberly R. Kalli, Scott H. Kaufmann, Cecile Le Page, Orla M. McNally, Jessica N. McAlpine, Linda Mileshkin, Jan Pyman, Goli Samimi, Ragwha Sharma, Ian G. Campbell

Publikováno v: Mod Pathol
Kang, E Y, Cheasley, D, Lepage, C, Wakefield, M J, Da Cunha Torres, M, Rowley, S, Salazar, C, Xing, Z, Allan, P, Bowtell, D D L, Mes-masson, A, Provencher, D M, Rahimi, K, Kelemen, L E, Fasching, P A, Doherty, J A, Goodman, M T, Goode, E L, Deen, S, Pharoah, P D P, Brenton, J D, Sieh, W, Mateoiu, C, Sundfeldt, K, Cook, L S, Le, N D, Anglesio, M S, Gilks, C B, Huntsman, D G, Kennedy, C J, Traficante, N, Defazio, A, Kaufmann, S, Churchman, M, Gourley, C, Stephens, A N, Meagher, N S, Ramus, S J, Antill, Y C, Campbell, I, Scott, C L, Köbel, M & Gorringe, K L 2020, ' Refined cut-off for TP53 immunohistochemistry improves prediction of TP53 mutation status in ovarian mucinous tumors: implications for outcome analyses ', Modern Pathology . https://doi.org/10.1038/s41379-020-0618-9

TP53 mutations are implicated in the progression of mucinous borderline tumors (MBOT) to mucinous ovarian carcinomas (MOC). Optimized immunohistochemistry (IHC) for TP53 has been established as a proxy for the TP53 mutation status in other ovarian tu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d1dbbb8d0c6aeaf0b4a7b60db78b77
https://doi.org/10.1038/s41379-020-0618-9

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Quantitative characterisation of ballistic cartridge cases from micro-CT

Autor: Mark A. Williams, K. Alsop, Danielle G. Norman, Paul Wilson, Guillaume Remy

Publikováno v: Forensic science international. 326

Evaluation of cartridge cases is essential within forensic ballistic analysis and is used in an attempt to establish a connection to the weapon used to fire it. This study consists of two experiments. The aims of Experiment 1 were to establish whethe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a67c06bc4285fd0c0b3ee6ab8627766
https://pubmed.ncbi.nlm.nih.gov/34311286

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Accurate prediction of saw blade thicknesses from false start measurements

Autor: B. Burnett, Mark A. Williams, K. Alsop, Danielle G. Norman, Waltraud Baier

Background:\ud False start analysis is the examination of incomplete saw marks created on bone in an effort to establish information on the saw that created them. The present study aims to use quantitative data from micro-CT cross-sections to predict

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1084739ce12d907bf12ba184ff81fd19

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