Zobrazeno 1 - 10
of 967
pro vyhledávání: '"K+ pump"'
Autor:
Michael J. McKenna, Xiaofei Gong, Aaron C. Petersen, Simon Sostaric, Craig A. Goodman, Andrew Garnham, Tai‐Juan Aw, Collene H. Steward, Kate T. Murphy, Kate A. Carey, Henry Krum, Rodney J. Snow, David Cameron‐Smith
Publikováno v:
Experimental Physiology, Vol 109, Iss 11, Pp 1909-1921 (2024)
Abstract In muscle, digoxin inhibits Na+,K+‐ATPase (NKA) whereas acute exercise can increase NKA gene expression, consistent with training‐induced increased NKA content. We investigated whether oral digoxin increased NKA isoform mRNA expression (
Externí odkaz:
https://doaj.org/article/cbd1bcf324d54266bf9e079ca206dcb1
Autor:
Parker J. Ellingson, Yousif O. Shams, Jessica R. Parker, Ronald L. Calabrese, Gennady S. Cymbalyuk
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
For animals to meet environmental challenges, the activity patterns of specialized oscillatory neural circuits, central pattern generators (CPGs), controlling rhythmic movements like breathing and locomotion, are adjusted by neuromodulation. As a rep
Externí odkaz:
https://doaj.org/article/46483948919849a7a2ed9c6acb33db53
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 135 (2024)
Na+,K+-ATPase actively extrudes three cytoplasmic Na+ ions in exchange for two extracellular K+ ions for each ATP hydrolyzed. The atomic structure with bound Na+ identifies three Na+ sites, named I, II, and III. It has been proposed that site III is
Externí odkaz:
https://doaj.org/article/8d61d63be8a847e59e1d525995cf6e1d
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16408 (2023)
Parkinson’s disease (PD) is a globally common progressive neurodegenerative disease resulting from the loss of dopaminergic neurons in the brain. Increased α-synuclein (α-syn) is associated with the degeneration of dopaminergic neurons and non-mo
Externí odkaz:
https://doaj.org/article/f557b468a6114e41a3b18c3489a2cef2
Autor:
Salvatore Sciacchitano, Carlo Capalbo, Christian Napoli, Andrea Negro, Luciano De Biase, Adriano Marcolongo, Paolo Anibaldi, Valentina Salvati, Lea Petrella, Luca Merlo, Daniela Alampi, Elisa Alessandri, Chiara Loffredo, Alessandra Ulivieri, Luca Lavra, Fiorenza Magi, Alessandra Morgante, Leila B. Salehi, Claudia De Vitis, Rita Mancini, Flaminia Coluzzi, Monica Rocco
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-18 (2021)
Abstract Background Nonthyroidal Illness Syndrome (NTIS) can be detected in many critical illnesses. Recently, we demonstrated that this condition is frequently observed in COVID-19 patients too and it is correlated with the severity the disease. How
Externí odkaz:
https://doaj.org/article/6a0564040064407393f87c777bb37eb4
Publikováno v:
Virulence, Vol 11, Iss 1, Pp 1415-1431 (2020)
ENA1 and ENA2 are P-type IID/ENA Na+/K+-ATPases required for cellular homeostasis in yeasts but remain poorly understood in filamentous fungal insect pathogens. Here, we characterized seven genes encoding five ENA1/2 homologues (ENA1a–c and ENA2a/b
Externí odkaz:
https://doaj.org/article/276837a09f564e1f856c393a3e13f7d9
Autor:
Holm, Rikke, Khandelwal, Jaanki, Einholm, Anja P., Andersen, Jens P., Artigas, Pablo, Vilsen, Bente
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2017 Jan 01. 114(2), 316-321.
Externí odkaz:
https://www.jstor.org/stable/26478711