Zobrazeno 1 - 10
of 18 357
pro vyhledávání: '"K+ CHANNELS"'
Autor:
Charlotte Mehlin Sorensen, Max Salomonsson, Anniek Frederike Lubberding, Niels‐Henrik Holstein‐Rathlou
Publikováno v:
Experimental Physiology, Vol 109, Iss 5, Pp 791-803 (2024)
Abstract The mechanisms behind renal vasodilatation elicited by stimulation of β‐adrenergic receptors are not clarified. As several classes of K channels are potentially activated, we tested the hypothesis that KV7 and BKCa channels contribute to
Externí odkaz:
https://doaj.org/article/43f3821a93b84390869f5c28eab8adf7
Autor:
Helmut Bischof, Selina Maier, Piotr Koprowski, Bogusz Kulawiak, Sandra Burgstaller, Joanna Jasińska, Kristian Serafimov, Monika Zochowska, Dominic Gross, Werner Schroth, Lucas Matt, David Arturo Juarez Lopez, Ying Zhang, Irina Bonzheim, Florian A Büttner, Falko Fend, Matthias Schwab, Andreas L Birkenfeld, Roland Malli, Michael Lämmerhofer, Piotr Bednarczyk, Adam Szewczyk, Robert Lukowski
Publikováno v:
eLife, Vol 12 (2024)
Alterations in the function of K+ channels such as the voltage- and Ca2+-activated K+ channel of large conductance (BKCa) reportedly promote breast cancer (BC) development and progression. Underlying molecular mechanisms remain, however, elusive. Her
Externí odkaz:
https://doaj.org/article/60f91b8d7664470fa1f56e117e4caef3
Autor:
Rahma Almallah, Hani Almukhtar
Publikováno v:
المجلة العراقية للصيدلة, Vol 20, Iss Supplementary Issue 1, Pp 195-200 (2023)
Background: Mirabegron operates through a distinct mechanism compared to antimuscarinic agents. Its activation of β3-adrenoceptors results in the relaxation of the bladder during the filling phase of micturition. The activation of β3-adrenoceptors,
Externí odkaz:
https://doaj.org/article/035db26e95724709b687dd7f6e2f608f
Publikováno v:
Polytechnic, Vol 12, Iss 1, Pp 67-78 (2023)
The current study represents the first attempt to investigate the effect of Adiantum capillus-veneris extract (ACVE) on goat’s isolated renal artery smooth muscle’s cell. Therefore, this research aims to investigate the possible action of Adiantu
Externí odkaz:
https://doaj.org/article/10e10635b1f340c3afeaebbbf79e55e0
Autor:
Maryam Owjfard, Negin Rahmani, Arashk Mallahzadeh, Mahnaz Bayat, Afshin Borhani-Haghighi, Farzaneh Karimi, Mohammad Reza Namavar
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e26640- (2024)
Nicorandil is a dual mechanism anti-anginal agent that acts as a nitric oxide (NO) donor and a potassium (K+) channel opener. Recent studies have evaluated the effect of nicorandil on ischemic stroke. Neurons have a low tolerance to hypoxia and there
Externí odkaz:
https://doaj.org/article/34aab71de19d416a8640bc2ebf2a5fa1
Autor:
Hosna Babini, Verónica Jiménez-Sábado, Ekaterina Stogova, Alia Arslanova, Mariam Butt, Saif Dababneh, Parisa Asghari, Edwin D. W. Moore, Thomas W. Claydon, Nipavan Chiamvimonvat, Leif Hove-Madsen, Glen F. Tibbits
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Atrial fibrillation (AF), the most common arrhythmia, has been associated with different electrophysiological, molecular, and structural alterations in atrial cardiomyocytes. Therefore, more studies are required to elucidate the genetic and molecular
Externí odkaz:
https://doaj.org/article/9fb5fce9358747888e15f06698dd86da
Akademický článek
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Publikováno v:
Neurobiology of Disease, Vol 188, Iss , Pp 106328- (2023)
Like a handful of other neuronal types in the brain, cholinergic neurons (CNs) in the pedunculopontine nucleus (PPN) are lost during Parkinson's disease (PD). Why this is the case is unknown. One neuronal trait implicated in PD selective neuronal vul
Externí odkaz:
https://doaj.org/article/679aeba49c7a426d935b556c9e89e93d
Publikováno v:
Journal of Pharmacological Sciences, Vol 150, Iss 4, Pp 211-222 (2022)
Canagliflozin, a sodium glucose co-transporter 2 (SGLT2) inhibitor, is reported to produce beneficial cardiovascular effects including a reduction in arterial contractility, and blood pressure. However, whether canagliflozin could directly relax resi
Externí odkaz:
https://doaj.org/article/8200b91bcfa14674be40422ddd894600