Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jyunichiro Yasukawa"'
Autor:
Hiroshi Hamamoto, Suresh Panthee, Atmika Paudel, Kenichi Ishii, Jyunichiro Yasukawa, Jie Su, Atsushi Miyashita, Hiroaki Itoh, Kotaro Tokumoto, Masayuki Inoue, Kazuhisa Sekimizu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Lysocin E is a lipopeptide with antibiotic activity against methicillin-resistant Staphylococcus aureus. Here, the authors show that the antimicrobial activity of lysocin E is potentiated through interactions with host serum proteins (such as apolipo
Externí odkaz:
https://doaj.org/article/b0d96c9f5e974962964e3a02e7b2c23b
Autor:
Shigeru Negi, Mami Hamori, Yuka Kawahara-Nakagawa, Masato Mashimo, Miki Imanishi, Nozomi Kuki, Yuri Kawahito, Takayuki Manabe, Nobuyuki Kawamura, Jyunichiro Yasukawa, Hiroaki Kitagishi, Yukio Sugiura
Publikováno v:
Chemistry Letters. 52:75-78
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::851fb188f5c12b818cc1600da38a7795
https://doi.org/10.1246/cl.220464
https://doi.org/10.1246/cl.220464
Autor:
Jie Su, Atmika Paudel, Jyunichiro Yasukawa, Kazuhisa Sekimizu, Hiroshi Hamamoto, Suresh Panthee, Atsushi Miyashita, Hiroaki Itoh, Masayuki Inoue, Kenichi Ishii, Kotaro Tokumoto
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications
Nature Communications
Lysocin E is a lipopeptide with antibiotic activity against methicillin-resistant Staphylococcus aureus. For unclear reasons, the antibacterial activity of lysocin E in a mouse systemic infection model is higher than expected from in vitro results, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b6078172ae48fc2ac70d0ae9a65f52
https://doaj.org/article/b0d96c9f5e974962964e3a02e7b2c23b
https://doaj.org/article/b0d96c9f5e974962964e3a02e7b2c23b
Autor:
Kenichi Ishii, Kotaro Tokumoto, Atmika Paudel, Kazuhisa Sekimizu, Jyunichiro Yasukawa, Hiroshi Hamamoto, Hiroaki Itoh, Masayuki Inoue, Su Jie, Suresh Panthee
The development of antimicrobials that exert therapeutic efficacy by novel mechanisms is crucial toward combatting multidrug-resistant bacteria. We previously reported a novel antibiotic, lysocin E, that is effective against methicillin-resistant Sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8287d09dac9de59a72c25fe4fb75afe7
https://doi.org/10.21203/rs.3.rs-89037/v1
https://doi.org/10.21203/rs.3.rs-89037/v1
Publikováno v:
PLoS Biology, Vol 5, Iss 5, p e118 (2007)
Despite its morphological similarity to the other species in the Drosophila melanogaster species complex, D. sechellia has evolved distinct physiological and behavioral adaptations to its host plant Morinda citrifolia, commonly known as Tahitian Noni
Externí odkaz:
https://doaj.org/article/1b443c20e89e4811a388e212a5193857
Autor:
Kazuhisa Sekimizu, Takuya Kaji, Jyunichiro Yasukawa, Motoki Murai, Hiroshi Hamamoto, Masayuki Inoue, Hiroaki Itoh
Publikováno v:
Chemistry - A European Journal. 22:16912-16919
Lysocin E (1) is a structurally complex 37-membered depsipeptide comprising 12 amino-acid residues with an N-methylated amide and an ester linkage. Compound 1 binds to menaquinone (MK) in the bacterial membrane to exert its potent bactericidal activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970b6709d02de0b4655eafc699a41c00
https://doi.org/10.1002/chem.201604022
https://doi.org/10.1002/chem.201604022
Publikováno v:
Birth Defects Research Part C: Embryo Today: Reviews. 108:33-44
Eukaryotes have evolved an array of membrane compartments constituting secretory and endocytic pathways that allow the flow of materials. Both pathways perform important regulatory roles. The secretory pathway is essential for the production of extra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8863a0fb008fd2eeb548b9bb86fd519
https://doi.org/10.1002/bdrc.21124
https://doi.org/10.1002/bdrc.21124
Autor:
Takefumi Kuranaga, Kenji Hamase, Kenichi Ishii, Tatsuo Adachi, Masayuki Inoue, Manabu Souma, Jyunichiro Yasukawa, Atmika Paudel, Makoto Urai, Motoki Murai, Hiroshi Tomoda, Hiroki Kurihara, Jie Su, Hiroshi Hamamoto, Takashi Katsu, Ryuji Uchida, Maki K. Yamada, Takuya Kaji, Kazuhisa Sekimizu
Publikováno v:
Nature Chemical Biology. 11:127-133
To obtain therapeutically effective new antibiotics, we first searched for bacterial culture supernatants with antimicrobial activity in vitro and then performed a secondary screening using the silkworm infection model. Through further purification o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ebe6cd3e640be459bca1700d37a522
https://doi.org/10.1038/nchembio.1710
https://doi.org/10.1038/nchembio.1710
Autor:
Yutaka Suzuki, Kenichi Ishii, Hiroshi Hamamoto, Kazuhisa Sekimizu, Jyunichiro Yasukawa, Tatsuo Adachi
Publikováno v:
Infection and Immunity. 82:1500-1510
We performed a genomewide analysis using a next-generation sequencer to investigate the effect of pulmonary surfactant on gene expression in Staphylococcus aureus , a clinically important opportunistic pathogen. RNA sequence (RNA-seq) analysis of bac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81bca7d4ba72db01f028be9c236c8c13
https://doi.org/10.1128/iai.01635-13
https://doi.org/10.1128/iai.01635-13
Autor:
Maki Iehara, Jie Su, Kazuhisa Sekimizu, Hiroshi Hamamoto, Jyunichiro Yasukawa, Yasuhiko Matsumoto
Publikováno v:
The Journal of Antibiotics. 68:646-648
A novel mutation in the vraS gene of Staphylococcus aureus contributes to reduce susceptibility against daptomycin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f7095e0514c995d12d4fd318fc681bb
https://doi.org/10.1038/ja.2015.42
https://doi.org/10.1038/ja.2015.42