Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jyun-Hung Chen"'
Publikováno v:
The Scientific World Journal, Vol 2015 (2015)
Virtual worlds (VWs) are computer-simulated environments which allow users to create their own virtual character as an avatar. With the rapidly growing user volume in VWs, platform providers launch virtual goods in haste and stampede users to increas
Externí odkaz:
https://doaj.org/article/63205dc52f6a4b91aa47330856430e3a
Publikováno v:
Key Engineering Materials. 732:69-75
(Na0.5Bi0.5)0.94Ba0.06TiO3 (NBBT) ceramics doped with 0.1∼2.0 mol.% Ba (Zr0.05Ti0.95)O3 were investigated in terms of the sintering, microstructure, phase transition, and piezoelectric properties. BZT doping has no remarkable effect on the microstr
Autor:
Jyun-Hung Chen, Thomas R. Caferro, Charlotte Pooley Deckhut, Lin Zhi, Christopher M. Tegley, Keith B. Marschke, Anthony W. Thompson, James P. Edwards, E. Adam Kallel, Marquis L. Cummings, Francisco J. López, William T. Schrader, Robert I. Higuchi, Mark E. Adams, Donald S. Karanewsky
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:5442-5446
A series of androgen receptor modulators based on 8H-[1,4]oxazino[2,3-f]quinolin-8-ones was synthesized and evaluated in an androgen receptor transcriptional activation assay. The most potent analogues from the series exhibited single-digit nanomolar
Autor:
Robert I. Higuchi, James P. Edwards, Min Wu, Jyun-Hung Chen, Chen Penghui, Neelakandha S. Mani
Publikováno v:
Tetrahedron Letters. 49:1903-1905
An efficient synthesis of the androgen receptor modulator ( R )- 4a having an 8 H -[1,4]oxazino[2,3- f ]quinolin-8-one skeleton is described. Synthesis of this ring system, not readily accessible by classical Knorr cyclization methodology, was accomp
Autor:
Jackline E. Dalgard, Andrew Hudson, Jyun-Hung Chen, Todd A. Miller, Thomas Lau, Richard J. Penuliar, Bao N. Nguyen, Dean P. Phillips, Matthew H. McNeill, Zhi Lin
Publikováno v:
ChemInform. 38
The coupling of aryl bromides or iodides with oxindoles using a copper iodide-N,N′-dimethylethylene diamine system is presented. The reaction proceeds efficiently and tolerates a variety of substitution patterns.
Autor:
Anne Reifel-Miller, Katheen M Ogilvie, Christopher M. Mapes, Mark D. Leibowitz, Donald S. Karanewsky, Marcus F. Boehm, Jyun-Hung Chen, Anthony W. Thompson, Robert Ardecky, Pierre-Yves Michellys, John S. Tyhonas, Sha Liu, Nathan Yumibe, Deepa Rungta, Timothy Alan Grese, Dale A. Mais
Publikováno v:
Bioorganicmedicinal chemistry letters. 13(22)
New RXR-selective modulators possessing a 6-fluoro trienoic acid moiety (6Z olefin) or a fluorinated/heterocyclic-substituted benzene core ring, were synthesized in an expedient and selective way. A subset of these compounds was evaluated for their m
Autor:
Pierre-Yves Michellys, Mark D Leibowitz, Marcus F. Boehm, Jennifer D'Arrigo, Anne Reifel-Miller, Christopher M. Mapes, Robert J. Ardecky, D.A. Mais, Chahrzad Montrose-Rafizadeh, Sha Liu, Donald S. Karanewsky, John S. Tyhonas, Deepa Rungta, Timothy Alan Grese, Jyun-Hung Chen, Anthony W. Thompson, Katheen M Ogilvie
Publikováno v:
Journal of medicinal chemistry. 46(19)
Retinoid X receptor:peroxisome proliferative-activated receptor (RXR:PPAR) heterodimers play a critical role in the regulation of glucose (RXR/PPARgamma) and lipid metabolism (RXR/PPARalpha). Previously, we described a concise structure-activity rela
Autor:
Christopher M. Mapes, Anthony W. Thompson, K Klausing, Anne Reifel-Miller, Robert Ardecky, Donald S. Karanewsky, Deepa Rungta, John S. Tyhonas, Mark D. Leibowitz, Timothy Alan Grese, Sha Liu, D.A. Mais, Margaret M. Faul, Garret J. Etgen, K B Marschke, A L Faulkner, Marcus F. Boehm, Jyun-Hung Chen, Pierre-Yves Michellys, Katheen M Ogilvie, D L Crombie, Richard A. Heyman
Publikováno v:
Journal of medicinal chemistry. 46(13)
Previous data have shown that RXR-selective agonists (e.g., 3 and 4) are insulin sensitizers in rodent models of non-insulin-dependent diabetes mellitus (NIDDM). Unfortunately, they also produce dramatic increases in triglycerides and profound suppre
Publikováno v:
ChemInform. 31
Publikováno v:
Journal of Applied Physics. 106:023530
The crystallization kinetics of a-Ge thin film induced by a thin Ni layer under thermal annealing and pulsed laser irradiation has been studied. Under thermal annealing, the crystallization temperature and activation energy for crystallization of a-G