Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jyun-Hung Chen"'
Publikováno v:
The Scientific World Journal, Vol 2015 (2015)
Virtual worlds (VWs) are computer-simulated environments which allow users to create their own virtual character as an avatar. With the rapidly growing user volume in VWs, platform providers launch virtual goods in haste and stampede users to increas
Externí odkaz:
https://doaj.org/article/63205dc52f6a4b91aa47330856430e3a
Publikováno v:
Key Engineering Materials. 732:69-75
(Na0.5Bi0.5)0.94Ba0.06TiO3 (NBBT) ceramics doped with 0.1∼2.0 mol.% Ba (Zr0.05Ti0.95)O3 were investigated in terms of the sintering, microstructure, phase transition, and piezoelectric properties. BZT doping has no remarkable effect on the microstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c2028b729bcbf96a7505d7649891be9
https://doi.org/10.4028/www.scientific.net/kem.732.69
https://doi.org/10.4028/www.scientific.net/kem.732.69
Autor:
Jyun-Hung Chen, Thomas R. Caferro, Charlotte Pooley Deckhut, Lin Zhi, Christopher M. Tegley, Keith B. Marschke, Anthony W. Thompson, James P. Edwards, E. Adam Kallel, Marquis L. Cummings, Francisco J. López, William T. Schrader, Robert I. Higuchi, Mark E. Adams, Donald S. Karanewsky
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:5442-5446
A series of androgen receptor modulators based on 8H-[1,4]oxazino[2,3-f]quinolin-8-ones was synthesized and evaluated in an androgen receptor transcriptional activation assay. The most potent analogues from the series exhibited single-digit nanomolar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb24be52ff66235cfadff901d5d77fd6
https://doi.org/10.1016/j.bmcl.2007.07.034
https://doi.org/10.1016/j.bmcl.2007.07.034
Publikováno v:
Helvetica Chimica Acta. 83:2607-2616
We have completed the total syntheses of elastase inhibitors YM-47141 and YM-47142, the first natural products containing a vicinal tricarbonyl group. The work establishes the configuration at C(4) of the macrocyclic depsipeptide and demonstrates the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7540e824ebd9624fc1ab2853d353c8dc
https://doi.org/10.1002/1522-2675(20000906)83:9<2607::aid-hlca2607>3.0.co
https://doi.org/10.1002/1522-2675(20000906)83:9<2607::aid-hlca2607>3.0.co
Autor:
Robert I. Higuchi, James P. Edwards, Min Wu, Jyun-Hung Chen, Chen Penghui, Neelakandha S. Mani
Publikováno v:
Tetrahedron Letters. 49:1903-1905
An efficient synthesis of the androgen receptor modulator ( R )- 4a having an 8 H -[1,4]oxazino[2,3- f ]quinolin-8-one skeleton is described. Synthesis of this ring system, not readily accessible by classical Knorr cyclization methodology, was accomp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd16845268058a51e4b986d27bd85680
https://doi.org/10.1016/j.tetlet.2008.01.114
https://doi.org/10.1016/j.tetlet.2008.01.114
Autor:
Jackline E. Dalgard, Andrew Hudson, Jyun-Hung Chen, Todd A. Miller, Thomas Lau, Richard J. Penuliar, Bao N. Nguyen, Dean P. Phillips, Matthew H. McNeill, Zhi Lin
Publikováno v:
ChemInform. 38
The coupling of aryl bromides or iodides with oxindoles using a copper iodide-N,N′-dimethylethylene diamine system is presented. The reaction proceeds efficiently and tolerates a variety of substitution patterns.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f285fb2fdbbc3a31b32aa79523ddf70c
https://doi.org/10.1002/chin.200702113
https://doi.org/10.1002/chin.200702113
Autor:
Anne Reifel-Miller, Katheen M Ogilvie, Christopher M. Mapes, Mark D. Leibowitz, Donald S. Karanewsky, Marcus F. Boehm, Jyun-Hung Chen, Anthony W. Thompson, Robert Ardecky, Pierre-Yves Michellys, John S. Tyhonas, Sha Liu, Nathan Yumibe, Deepa Rungta, Timothy Alan Grese, Dale A. Mais
Publikováno v:
Bioorganicmedicinal chemistry letters. 13(22)
New RXR-selective modulators possessing a 6-fluoro trienoic acid moiety (6Z olefin) or a fluorinated/heterocyclic-substituted benzene core ring, were synthesized in an expedient and selective way. A subset of these compounds was evaluated for their m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c260917cabd1b5b16aa3a9de63ed3bc
https://pubmed.ncbi.nlm.nih.gov/14592510
https://pubmed.ncbi.nlm.nih.gov/14592510
Autor:
Pierre-Yves Michellys, Mark D Leibowitz, Marcus F. Boehm, Jennifer D'Arrigo, Anne Reifel-Miller, Christopher M. Mapes, Robert J. Ardecky, D.A. Mais, Chahrzad Montrose-Rafizadeh, Sha Liu, Donald S. Karanewsky, John S. Tyhonas, Deepa Rungta, Timothy Alan Grese, Jyun-Hung Chen, Anthony W. Thompson, Katheen M Ogilvie
Publikováno v:
Journal of medicinal chemistry. 46(19)
Retinoid X receptor:peroxisome proliferative-activated receptor (RXR:PPAR) heterodimers play a critical role in the regulation of glucose (RXR/PPARgamma) and lipid metabolism (RXR/PPARalpha). Previously, we described a concise structure-activity rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eea8b4fbbc3b55ea587ba9594c00647
https://pubmed.ncbi.nlm.nih.gov/12954061
https://pubmed.ncbi.nlm.nih.gov/12954061
Autor:
Christopher M. Mapes, Anthony W. Thompson, K Klausing, Anne Reifel-Miller, Robert Ardecky, Donald S. Karanewsky, Deepa Rungta, John S. Tyhonas, Mark D. Leibowitz, Timothy Alan Grese, Sha Liu, D.A. Mais, Margaret M. Faul, Garret J. Etgen, K B Marschke, A L Faulkner, Marcus F. Boehm, Jyun-Hung Chen, Pierre-Yves Michellys, Katheen M Ogilvie, D L Crombie, Richard A. Heyman
Publikováno v:
Journal of medicinal chemistry. 46(13)
Previous data have shown that RXR-selective agonists (e.g., 3 and 4) are insulin sensitizers in rodent models of non-insulin-dependent diabetes mellitus (NIDDM). Unfortunately, they also produce dramatic increases in triglycerides and profound suppre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0a076facd0899614067ed9d41533cd
https://pubmed.ncbi.nlm.nih.gov/12801232
https://pubmed.ncbi.nlm.nih.gov/12801232
Publikováno v:
ChemInform. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::758fe85de76bd936ce8f8764ae691841
https://doi.org/10.1002/chin.200052175
https://doi.org/10.1002/chin.200052175