Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jyue Yuan Lim"'
Autor:
Françoise Bachelerie, Matthew F. Krummel, Jyue Yuan Lim, Yiru Zhang, Ka Hang Liong, Peter See, Akhila Balachander, Johan Duchene, Mariaelvy Bianchini, Josephine Lum, Qingfeng Chen, Mark R. Looney, Jackson LiangYao Li, Adrian Boey, Christian Weber, Maximilien Evrard, José M. Adrover, Michael Poidinger, Wolfgang Weninger, Anis Larbi, Lai Guan Ng, Laurent Rénia, Andrés Hidalgo, Suet-Mien Tan, John E. Harris, Leonard Tan, Karl Balabanian, Jerry Kok Yen Chan, Bernett Lee, Cheng-I Wang, Shu Zhen Chong, Cindy Phua, Gwendalyn J. Randolph, Jinmiao Chen, Sapna Devi, David Liebl, Florent Ginhoux, Subhra K. Biswas
Publikováno v:
The Journal of experimental medicine, vol 213, iss 11
The Journal of Experimental Medicine
Repisalud
Instituto de Salud Carlos III (ISCIII)
The Journal of Experimental Medicine
Repisalud
Instituto de Salud Carlos III (ISCIII)
CXCR4 identifies an immobilized BM precursor (i.e., transitional premonocyte [TpMo]) that proliferates and replenishes mature Ly6Chi monocytes in mice and humans. Upon entering the circulation, CXCR4 governs monocyte margination in the lung vasculatu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20481e432de5cf2c242c9853098769a2
https://escholarship.org/uc/item/1j84k5m5
https://escholarship.org/uc/item/1j84k5m5
Publikováno v:
Immunologic Research. 53:11-24
The role of myelomonocytic cells like monocytes and macrophages as first line of host defense is well established. Recent understanding of these cells using systems biology, transgenesis and in disease models has brought them to a center stage in orc
Autor:
Carolina Cubillos-Zapata, Annelies S. Zinkernagel, Victor Toledano, Annamaria Rapisarda, Irina N. Shalova, Eduardo López-Collazo, Jyue Yuan Lim, Federico C. Beasley, Subhra K. Biswas, Enrique Hernández-Jiménez, Francisco Arnalich, Kaibo Duan, Victor Nizet, Jinmiao Chen, Giovanni Melillo, Manesh Chittezhath, Michael Poidinger, Henry Yang
SummarySepsis is characterized by a dysregulated inflammatory response to infection. Despite studies in mice, the cellular and molecular basis of human sepsis remains unclear and effective therapies are lacking. Blood monocytes serve as the first lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e75fe27e36857cdc357ff5911ce1d343
https://doi.org/10.5167/uzh-114558
https://doi.org/10.5167/uzh-114558
Autor:
Thomas Paulraj Thamboo, Alvin Wong, Michael Poidinger, Manesh Chittezhath, Jyue Yuan Lim, Henry Yang, Edmund Chiong, Francesca Zolezzi, Manprit Kaur Dhillon, Yi Ling Teo, Jo A. Van Ginderachter, Jinmiao Chen, Subhra K. Biswas, Josephine Lum, Irina N. Shalova, Damya Laoui, Revathy Kamaraj, Lata Raman
Publikováno v:
Vrije Universiteit Brussel
SummaryMonocytes and macrophages are major components of the tumor microenvironment, but their contributions to human cancer are poorly understood. We used molecular profiling combined with functional assays to investigate the role of these cells in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::673030ab333af7fcff2a86f918192df0
https://biblio.vub.ac.be/vubir/molecular-profiling-reveals-a-tumorpromoting-phenotype-of-monocytes-and-macrophages-in-human-cancer-progression(b4284508-1853-4eb1-b306-8488ace51608).html
https://biblio.vub.ac.be/vubir/molecular-profiling-reveals-a-tumorpromoting-phenotype-of-monocytes-and-macrophages-in-human-cancer-progression(b4284508-1853-4eb1-b306-8488ace51608).html
Publikováno v:
Cell stresschaperones. 20(4)
Febrile temperatures can induce stress responses which protect cells from damage and can reduce inflammation during infections and sepsis. However, the mechanisms behind the protective functions of heat in response to the bacterial endotoxin LPS are
Autor:
Irina N. Shalova, Jyue Yuan Lim, Subhra K. Biswas, Francisco Arnalich, Philip Iau, Irene Fernández-Ruiz, Tasneem Kajiji, Vanesa Gómez-Piña, Siew Cheng Wong, Eduardo López-Collazo
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 188(8)
Blood monocytes recognize Gram-negative bacteria through the TLR4, which signal via MyD88- and TRIF-dependent pathway to trigger an immune-inflammatory response. However, a dysregulated inflammatory response by these cells often leads to severe patho