Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Jyrki J. Eloranta"'
Autor:
Irina V. Tcymbarevich, Jyrki J. Eloranta, Jean-Benoît Rossel, Nicole Obialo, Marianne Spalinger, Jesus Cosin-Roger, Silvia Lang, Gerd A. Kullak-Ublick, Carsten A. Wagner, Michael Scharl, Klaus Seuwen, Pedro A. Ruiz, Gerhard Rogler, Cheryl de Vallière, Benjamin Misselwitz, on behalf of the Swiss IBD Cohort Study Group
Publikováno v:
BMC Gastroenterology, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Tissue inflammation in inflammatory bowel diseases (IBD) is associated with a decrease in local pH. The gene encoding G-protein-coupled receptor 65 (GPR65) has recently been reported to be a genetic risk factor for IBD. In respons
Externí odkaz:
https://doaj.org/article/6941ccbb826442539db66cc0037811fa
Autor:
Cheryl de Vallière, Jesus Cosin-Roger, Simona Simmen, Kirstin Atrott, Hassan Melhem, Jonas Zeitz, Mehdi Madanchi, Irina Tcymbarevich, Michael Fried, Gerd A. Kullak-Ublick, Stephan R. Vavricka, Benjamin Misselwitz, Klaus Seuwen, Carsten A. Wagner, Jyrki J. Eloranta, Gerhard Rogler, Pedro A. Ruiz
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 6, Pp 796-810 (2016)
Background & Aims: A novel family of proton-sensing G-proteinâcoupled receptors, including ovarian cancer G-proteinâcoupled receptor 1 (OGR1) (GPR68) has been identified to play a role in pH homeostasis. Hypoxia is known to change tissue pH as a re
Externí odkaz:
https://doaj.org/article/7a3bd9560e9e42fda27043e39740354d
Autor:
Ragam Gerster, Jyrki J. Eloranta, Martin Hausmann, Pedro A. Ruiz, Jesus Cosin-Roger, Anne Terhalle, Urs Ziegler, Gerd A. Kullak-Ublick, Arnold von Eckardstein, Gerhard Rogler
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 2, Pp 171-187.e1 (2015)
Background & Aims: Plasma levels of high-density lipoprotein (HDL) cholesterol are frequently found decreased in patients with inflammatory bowel disease (IBD). Therefore, and because HDL exerts anti-inflammatory activities, we investigated whether H
Externí odkaz:
https://doaj.org/article/390a5180ae034d80941b582d44da4e8f
Publikováno v:
PPAR Research, Vol 2012 (2012)
PPARγ is a nuclear receptor that regulates numerous pathways including cytokine expression and immune responses and plays an important role in controlling colon inflammation. We aimed at determining the occurring PPARγ SNPs, at predicting the haplo
Externí odkaz:
https://doaj.org/article/5f5713a252e7481b9ccd7e211020c13f
Autor:
Gerhard Rogler, Pedro A. Ruiz, Cheryl de Valliere, Jonas Zeitz, Jyrki J. Eloranta, Hassan Melhem, Irina Tcymbarevich, Kirstin Atrott, Benjamin Misselwitz, Gerd A. Kullak-Ublick, Michael Fried, Klaus Seuwen, Carsten A. Wagner, Mehdi Madanchi, Jesus Cosin-Roger, Simona Simmen, Stephan R. Vavricka
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 6, Pp 796-810 (2016)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims: A novel family of proton-sensing G-proteinâcoupled receptors, including ovarian cancer G-proteinâcoupled receptor 1 (OGR1) (GPR68) has been identified to play a role in pH homeostasis. Hypoxia is known to change tissue pH as a re
Autor:
Daniel Konrad, François Pattou, Christoph H. Westphal, Andrea Patrignani, Camille Regairaz, Marianne Böni-Schnetzler, Claudia Cavelti-Weder, Jyrki J. Eloranta, Adriano Fontana, Cornelia Keller, Marc Y. Donath, Caroline Brorsson, Monika Meyer-Böni, Urs Knobel, Gil Leibowitz, James L. Ellis, Katharina Timper, Gerhard Rogler, Flemming Pociot, Rémy Bruggmann, Jennifer Cermak, Andrea Brunner, Andreas Geier, Michael W. McBurney, David A. Sinclair, Henryk Zulewski, José M. Carballido, Peter J. Elliott, Karim Bouzakri, Ralph Schlapbach, Daniel T. Meier, Basil P. Hubbard, Benjamin Glaser, Anna Biason-Lauber, Christian M. Matter, Julie Kerr-Conte, Gino Boily
Publikováno v:
Cell metabolism
Cell Metabolism, Vol. 17, No 3 (2013) pp. 448-55
Biason-Lauber, Anna; Böni-Schnetzler, Marianne; Hubbard, Basil P.; Bouzakri, Karim; Brunner, Andrea; Cavelti-Weder, Claudia; Keller, Cornelia; Meyer-Böni, Monika; Meier, Daniel T.; Brorsson, Caroline; Timper, Katharina; Leibowitz, Gil; Patrignani, Andrea; Bruggmann, Rémy; Boily, Gino; Zulewski, Henryk; Geier, Andreas; Cermak, Jennifer M; Elliott, Peter; Ellis, James L.; ... (2013). Identification of a SIRT1 mutation in a family with type 1 diabetes. Cell metabolism, 17(3), pp. 448-455. Cell Press 10.1016/j.cmet.2013.02.001
Cell Metabolism, Vol. 17, No 3 (2013) pp. 448-55
Biason-Lauber, Anna; Böni-Schnetzler, Marianne; Hubbard, Basil P.; Bouzakri, Karim; Brunner, Andrea; Cavelti-Weder, Claudia; Keller, Cornelia; Meyer-Böni, Monika; Meier, Daniel T.; Brorsson, Caroline; Timper, Katharina; Leibowitz, Gil; Patrignani, Andrea; Bruggmann, Rémy; Boily, Gino; Zulewski, Henryk; Geier, Andreas; Cermak, Jennifer M; Elliott, Peter; Ellis, James L.; ... (2013). Identification of a SIRT1 mutation in a family with type 1 diabetes. Cell metabolism, 17(3), pp. 448-455. Cell Press 10.1016/j.cmet.2013.02.001
SummaryType 1 diabetes is caused by autoimmune-mediated β cell destruction leading to insulin deficiency. The histone deacetylase SIRT1 plays an essential role in modulating several age-related diseases. Here we describe a family carrying a mutation
Publikováno v:
Molecular Pharmacology
Organic anion-transporting polypeptide 1A2 (OATP1A2) (gene symbol, SLCO1A2) mediates cellular uptake of a wide range of endogenous substrates, as well as drugs and xenobiotics. OATP1A2 is expressed in several tissues, including apical membranes of sm
Publikováno v:
Mwinyi, Jessica; Grete-Wenger, Christa; Eloranta, Jyrki J.; Kullak-Ublick, Gerd A. (2012). The Impact of PPARγ Genetic Variants on IBD Susceptibility and IBD Disease Course. PPAR Research, 2012, p. 349469. New York, N.Y.: Hindawi Publishing Corporation 10.1155/2012/349469
PPAR Research, Vol 2012 (2012)
PPAR Research
PPAR Research, Vol 2012 (2012)
PPAR Research
PPARγ is a nuclear receptor that regulates numerous pathways including cytokine expression and immune responses and plays an important role in controlling colon inflammation. We aimed at determining the occurringPPARγ SNPs, at predicting the haplot
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology
The apical sodium-dependent bile acid transporter (ASBT) is expressed abundantly in the ileum and mediates bile acid absorption across the apical membranes. Caudal-type homeobox proteins CDX1 and CDX2 are transcription factors that regulate genes inv
Autor:
Jyrki J. Eloranta, Wolfgang Patsch, Katja Klein, Franz Krempler, Jessica Mwinyi, Christoph Jüngst, Gerd A. Kullak-Ublick, Bruno Stieger
Publikováno v:
Molecular pharmacology
Organic anion transporters (OATs) are anion exchangers that transport small hydrophilic anions and diuretics, antibiotics, nonsteroidal anti-inflammatory drugs, antiviral nucleoside analogs, and antitumor drugs across membrane barriers of epithelia o