Výsledky vyhledávání - "Jyoti W. Watters"

Metabolic response of microglia to amyloid deposition during Alzheimer’s disease progression in a mouse model

Autor: Kaitlyn M. Marino, Jayne M. Squirrell, Jenu V. Chacko, Jyoti W. Watters, Kevin W. Eliceiri, Tyler K. Ulland

SummaryAlzheimer’s disease (AD) drives metabolic changes in the central nervous system (CNS). In AD microglia are activated and proliferate in response to amyloid β plaques. To further characterize the metabolic changes in microglia associated wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aea9e28d906fca440ea40b15f34fec18
https://doi.org/10.1101/2023.05.12.540407

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Mutation of a Dibasic Amino Acid Motif Within the C Terminus of the P2X7 Nucleotide Receptor Results in Trafficking Defects and Impaired Function

Autor: George R. Dubyak, Loren C. Denlinger, Karen Parker, Jyoti W. Watters, Paul J. Bertics, Philip L. Fisette, Julie A. Sommer, Lalitha Gudipaty, Richard A. Proctor

Publikováno v: The Journal of Immunology. 171:1304-1311

Activation of the P2X7 receptor by extracellular nucleotides modulates multiple immune functions, including inflammatory mediator production, membrane fusion events, and apoptosis. Previous studies have revealed that the C terminus of this multimeric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99065a70e01176c59b81d6a93a0db97e
https://doi.org/10.4049/jimmunol.171.3.1304

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