Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jyoti R. Misra"'
Autor:
Hui Chen, Artem Gridnev, Netanya Schlamowitz, Wanyi Hu, Kuntala Dey, Guangrong Zheng, Jyoti R. Misra
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37829- (2024)
The transcription factors, TEAD1-4 together with their co-activator YAP/TAZ function as key downstream effectors of the Hippo pathway. Hyperactivation of TEAD-YAP/TAZ activity is observed in many human cancers. TEAD1-4 possess distinct physiological
Externí odkaz:
https://doaj.org/article/04f8c3a78de34b3d8febf7c018afff4d
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The paralogous oncogenic transcriptional coactivators YAP and TAZ are the distal effectors of the Hippo signaling pathway, which plays a critical role in cell proliferation, survival and cell fate specification. They are frequently deregulated in mos
Externí odkaz:
https://doaj.org/article/1d6482387d174a3f8c9e7eefcb9ca425
Autor:
Artem Gridnev, Jyoti R. Misra
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Dachsous (Ds) and Fat are evolutionarily conserved cell adhesion molecules that play a critical role in development of multiple organ systems, where they coordinate tissue growth and morphogenesis. Much of our understanding of Ds-Fat signaling pathwa
Externí odkaz:
https://doaj.org/article/c250806d6a1842869a7d2e33a3b18314
Autor:
Artem Gridnev, Jyoti R. Misra
Publikováno v:
Frontiers in cell and developmental biology. 10
Dachsous (Ds) and Fat are evolutionarily conserved cell adhesion molecules that play a critical role in development of multiple organ systems, where they coordinate tissue growth and morphogenesis. Much of our understanding of Ds-Fat signaling pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20dc18fcd854f8129a932e679ee6a5d8
https://pubmed.ncbi.nlm.nih.gov/35372364
https://pubmed.ncbi.nlm.nih.gov/35372364
Publikováno v:
Cancers. 14:1029
YAP/TAZ are transcriptional coactivators that function as the key downstream effectors of Hippo signaling. They are commonly misregulated in most human cancers, which exhibit a higher level of expression and nuclear localization of YAP/TAZ, and displ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595e96fcf6c0213395b0266ea0cedba5
https://doi.org/10.3390/cancers14041029
https://doi.org/10.3390/cancers14041029
Autor:
Kenneth D. Irvine, Jyoti R. Misra
Publikováno v:
PLoS Genetics, Vol 15, Iss 1, p e1007955 (2019)
PLoS Genetics
PLoS Genetics
The Drosophila protocadherins Dachsous and Fat regulate growth and tissue polarity by modulating the levels, membrane localization and polarity of the atypical myosin Dachs. Localization to the apical junctional membrane is critical for Dachs functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee5a6fcff64aa0774c29344b702e7505
https://doaj.org/article/e0a0e2e3306542a7a9d661d4807dfc76
https://doaj.org/article/e0a0e2e3306542a7a9d661d4807dfc76
Autor:
Kenneth D. Irvine, Jyoti R. Misra
Publikováno v:
Developmental Cell. 39:254-266
Summary The protocadherins Dachsous and Fat initiate a signaling pathway that controls growth and planar cell polarity by regulating the membrane localization of the atypical myosin Dachs. How Dachs is regulated by Fat signaling has remained unclear.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536309abf7a3e1341e51030b095333e7
https://doi.org/10.1016/j.devcel.2016.09.017
https://doi.org/10.1016/j.devcel.2016.09.017
Autor:
Kenneth D. Irvine, Jyoti R. Misra
Hippo signaling is an evolutionarily conserved network that has a central role in regulating cell proliferation and cell fate to control organ growth and regeneration. It promotes activation of the LATS kinases, which control gene expression by inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d4648ffc073f4cce1d2d2a8a6db6a54
https://europepmc.org/articles/PMC6322405/
https://europepmc.org/articles/PMC6322405/
Publikováno v:
Insect Biochemistry and Molecular Biology. 43:1116-1124
Pesticide resistance poses a major challenge for the control of vector-borne human diseases and agricultural crop protection. Although a number of studies have defined how mutations in specific target proteins can lead to insecticide resistance, much
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd77a2af36f00c41df281c845ab4cc5
https://doi.org/10.1016/j.ibmb.2013.09.005
https://doi.org/10.1016/j.ibmb.2013.09.005
Publikováno v:
Biophysical Chemistry. 137:13-18
The GTPase effector domain (GED) of dynamin forms large soluble oligomers in vitro, while its mutant--I697A--lacks this property at low concentrations. With a view to understand the intrinsic structural characteristics of the polypeptide chain, the g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf6b3dde8adc7d62ab383bfe3b7f29fd
https://doi.org/10.1016/j.bpc.2008.06.005
https://doi.org/10.1016/j.bpc.2008.06.005