Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jyoti K. Jha"'
Autor:
Ananta Prasad Arukha, Christian Furlan Freguia, Meerambika Mishra, Jyoti K. Jha, Subhashinie Kariyawasam, Neil A. Fanger, Ellen M. Zimmermann, Gary R. Fanger, Bikash Sahay
Publikováno v:
Biomedicines, Vol 9, Iss 9, p 1098 (2021)
Inflammatory bowel disease (IBD) is characterized by gastrointestinal inflammation comprised of Crohn’s disease and ulcerative colitis. Centers for Disease Control and Prevention report that 1.3% of the population of the United States (approximatel
Externí odkaz:
https://doaj.org/article/87ebad7bd9a942dfa799de5cc4e70af1
Autor:
Jyoti K. Jha, Mi Li, Rodolfo Ghirlando, Lisa M. Miller Jenkins, Alexander Wlodawer, Dhruba Chattoraj
Publikováno v:
mBio, Vol 8, Iss 2 (2017)
ABSTRACT Replication of Vibrio cholerae chromosome 2 (Chr2) depends on molecular chaperone DnaK to facilitate binding of the initiator (RctB) to the replication origin. The binding occurs at two kinds of site, 12-mers and 39-mers, which promote and i
Externí odkaz:
https://doaj.org/article/b5d96285835341098d25f2238b1b137f
Publikováno v:
PLoS Genetics, Vol 14, Iss 5, p e1007426 (2018)
Initiation of chromosome replication in bacteria is precisely timed in the cell cycle. Bacteria that harbor multiple chromosomes face the additional challenge of orchestrating replication initiation of different chromosomes. In Vibrio cholerae, the s
Externí odkaz:
https://doaj.org/article/5a8f64616a124d439ad595050a85b13e
Autor:
Jyoti K Jha, Dhruba K Chattoraj
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0166722 (2016)
The Escherichia coli origin of replication, oriC, comprises mostly binding sites of two proteins: DnaA, a positive regulator, and SeqA, a negative regulator. SeqA, although not essential, is required for timely initiation, and during rapid growth, sy
Externí odkaz:
https://doaj.org/article/bf8d76af4c5e40dfa8e21629394218e7
Publikováno v:
Nucleic Acids Res
Studies of bacterial chromosomes and plasmids indicate that their replication initiator proteins bind to origins of replication at many double-stranded sites and also at AT-rich regions where single-stranded DNA is exposed during origin opening. Sing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff5ad7841ac302808f21245916dfe19
https://doi.org/10.1093/nar/gkaa826
https://doi.org/10.1093/nar/gkaa826
Autor:
Jyoti K. Jha, Ji-Dung Luo, Gary R. Fanger, Matthew E. Griffin, Juliel Espinosa, Thomas L. Carroll, Howard C. Hang, Jessica L. Becker
Publikováno v:
Science
The antitumor efficacy of cancer immunotherapy can correlate with the presence of certain bacterial species within the gut microbiome. However, many of the molecular mechanisms that influence host response to immunotherapy remain elusive. In this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13999a2201c6de216e09431f24655aaf
https://europepmc.org/articles/PMC9503018/
https://europepmc.org/articles/PMC9503018/
Autor:
Christopher B. Stanley, Kevin L. Weiss, Digvijay Patil, Jyoti K. Jha, Pankaj Kumar, Elliott Crooke, Rahul Saxena, Matthew J. Cuneo, Dhruba K. Chattoraj
Publikováno v:
Nucleic Acids Research
Escherichia coli replication initiator protein DnaA binds ATP with high affinity but the amount of ATP required to initiate replication greatly exceeds the amount required for binding. Previously, we showed that ATP-DnaA, not ADP-DnaA, undergoes a co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f0c61bdd5639a146e3a48411c3f5b4
http://europepmc.org/articles/PMC7145717
http://europepmc.org/articles/PMC7145717
Autor:
Jessica L. Becker, Gary R. Fanger, Juliel Espinosa, Jyoti K. Jha, Matthew E. Griffin, Howard C. Hang
The antitumor efficacy of cancer immunotherapy has been correlated with specific species within the gut microbiota. However, molecular mechanisms by which these microbes affect host response to immunotherapy remain elusive. Here we show that specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef4cd7d5910cf9152f9e88390a9405b5
https://doi.org/10.1101/2020.08.20.256263
https://doi.org/10.1101/2020.08.20.256263
Autor:
Seth J. Corey, Mungunsukh Ognoon, Thomas A. Summers, Hrishikesh M Mehta, Elizabeth A McCart, William B. Rittase, Jeffy George, Jyoti K. Jha, Regina M. Day, Michelle A. Bylicky, Joseph J. Mattapallil
Publikováno v:
Journal of Cellular and Molecular Medicine. 22:4274-4282
Allogeneic stem cell transplantation is currently the only curative therapy for primary myelofibrosis (MF), while the JAK2 inhibitor, ruxolitinib. Has been approved only for palliation. Other therapies are desperately needed to reverse life‐threate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bc3b557824818a789b592f9c1087f8a
https://doi.org/10.1111/jcmm.13710
https://doi.org/10.1111/jcmm.13710
Autor:
Gary R. Fanger, Meerambika Mishra, Subhashinie Kariyawasam, Christian Furlan Freguia, Ellen M. Zimmermann, Ananta Prasad Arukha, Jyoti K. Jha, Bikash Sahay, Neil Fanger
Publikováno v:
Biomedicines
Volume 9
Issue 9
Biomedicines, Vol 9, Iss 1098, p 1098 (2021)
Volume 9
Issue 9
Biomedicines, Vol 9, Iss 1098, p 1098 (2021)
Inflammatory bowel disease (IBD) is characterized by gastrointestinal inflammation comprised of Crohn’s disease and ulcerative colitis. Centers for Disease Control and Prevention report that 1.3% of the population of the United States (approximatel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::067779a28b23d86b27c9522a746ca338
https://doi.org/10.3390/biomedicines9091098
https://doi.org/10.3390/biomedicines9091098