Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Jyoti J, Watters"'
Autor:
Maria Nikodemova, Jose R. Oberto, Ethan L. Kaye, Mackenzie R. Berschel, Alysha L. Michaelson, Jyoti J. Watters, Gordon S. Mitchell
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-12 (2024)
Abstract Background Adverse events in early life can have impact lasting into adulthood. We investigated the long-term effects of systemic inflammation during postnatal development on adult microglial responses to lipopolysaccharide (LPS) in two CNS
Externí odkaz:
https://doaj.org/article/8089803008934e239d07ccad8b063cfb
Autor:
Danuzia Ambrozio‐Marques, Marianne Gagnon, Abigail B. Radcliff, Armand L. Meza, Tracy L. Baker, Jyoti J. Watters, Richard Kinkead
Publikováno v:
Experimental Physiology, Vol 108, Iss 11, Pp 1376-1385 (2023)
Abstract Sleep‐disordered breathing is a respiratory disorder commonly experienced by pregnant women. The recurrent hypoxaemic events associated with sleep‐disordered breathing have deleterious consequences for the mother and fetus. Adult male (b
Externí odkaz:
https://doaj.org/article/f78afbf676ab4ca99b23fc67e10e655f
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1852 (2024)
Obstructive sleep apnea (OSA), a respiratory sleep disorder associated with cardiovascular diseases, is more prevalent in men. However, OSA occurrence in pregnant women rises to a level comparable to men during late gestation, creating persistent eff
Externí odkaz:
https://doaj.org/article/6a8598cf1e804e16b8b5be6a44276019
Autor:
Jaitri Joshi, Yue Xiong, Molly Kuhn, Abigail B. Radcliff, Tracy L. Baker, Jyoti J. Watters, Lisa M. Arendt
Publikováno v:
Cells, Vol 13, Iss 3, p 249 (2024)
An adverse perinatal environment can increase long-term cancer risk, although the precise nature of associated perinatal triggers remain unknown. Sleep apnea is a common condition during pregnancy, characterized by recurrent cessations in breathing d
Externí odkaz:
https://doaj.org/article/72319eee0568417b891dc19932da3979
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background Alzheimer’s disease (AD) is a neurodegenerative disorder and is the most common cause of late-onset dementia. Microglia, the primary innate immune cells of the central nervous system (CNS), have a complex role in AD neuropatholo
Externí odkaz:
https://doaj.org/article/3a87c6f4d7a34adba0afccb2effc5c3b
Autor:
Lopamudra Mukherjee, Md Abdul Kader Sagar, Jonathan N. Ouellette, Jyoti J. Watters, Kevin W. Eliceiri
Publikováno v:
Frontiers in Neuroinformatics, Vol 16 (2022)
Microglia are the immune cell in the central nervous system (CNS) and exist in a surveillant state characterized by a ramified form in the healthy brain. In response to brain injury or disease including neurodegenerative diseases, they become activat
Externí odkaz:
https://doaj.org/article/7d743d0493d440449f4ed5c3114509b7
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Endogenous opioid peptides activating mu-opioid receptors (MORs) are part of an intricate neuromodulatory system that coordinates and optimizes respiratory motor output to maintain blood-gas homeostasis. MOR activation is typically associated with re
Externí odkaz:
https://doaj.org/article/a079d47e849640e2b921655ce66703c3
Autor:
Amanda M Vanderplow, Bailey A Kermath, Cassandra R Bernhardt, Kimberly T Gums, Erin N Seablom, Abigail B Radcliff, Andrea C Ewald, Mathew V Jones, Tracy L Baker, Jyoti J Watters, Michael E Cahill
Publikováno v:
PLoS Biology, Vol 20, Iss 2, p e3001502 (2022)
Mounting epidemiologic and scientific evidence indicates that many psychiatric disorders originate from a complex interplay between genetics and early life experiences, particularly in the womb. Despite decades of research, our understanding of the p
Externí odkaz:
https://doaj.org/article/6bdadc7aaaae46f489eacd9c72cf88bc
Autor:
Elizabeth A. Kiernan, Andrea C. Ewald, Jonathan N. Ouellette, Tao Wang, Abiye Agbeh, Andrew O. Knutson, Avtar S. Roopra, Jyoti J. Watters
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Hypoxia (Hx) is a component of multiple disorders, including stroke and sleep-disordered breathing, which often precede or are comorbid with neurodegenerative diseases. However, little is known about how hypoxia affects the ability of microglia, resi
Externí odkaz:
https://doaj.org/article/f463f2fae277427f9d6f4e69cad1a948
Autor:
Md Abdul Kader Sagar, Kevin P. Cheng, Jonathan N. Ouellette, Justin C. Williams, Jyoti J. Watters, Kevin W. Eliceiri
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Automated computational analysis techniques utilizing machine learning have been demonstrated to be able to extract more data from different imaging modalities compared to traditional analysis techniques. One new approach is to use machine learning t
Externí odkaz:
https://doaj.org/article/b16f2045740d4115ba578b342ed69004