Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jyoti Bikram Chhetri"'
Autor:
Jason P. Wray, Elitza M. Deltcheva, Charlotta Boiers, Simon Е Richardson, Jyoti Bikram Chhetri, John Brown, Sladjana Gagrica, Yanping Guo, Anuradha Illendula, Joost H. A. Martens, Hendrik G. Stunnenberg, John H. Bushweller, Rachael Nimmo, Tariq Enver
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The ETV6-RUNX1 chimeric- and native RUNX1-responsive regulomes in paediatric B-acute lymphoblastic leukemia (B-ALL) remain to be characterized. Here, the authors reveal functional antagonism between the two transcription factors predominantly for the
Externí odkaz:
https://doaj.org/article/57a324404a3a49c69acb08a4d571d807
Publikováno v:
Biology, Vol 12, Iss 11, p 1419 (2023)
Adoptive cell therapy (ACT) has transformed the treatment landscape for cancer and infectious disease through the investigational use of chimeric antigen receptor T-cells (CAR-Ts), tumour-infiltrating lymphocytes (TILs) and viral-specific T-cells (VS
Externí odkaz:
https://doaj.org/article/aa627412fcdf4afcbf18d927567a5498
Autor:
Jason P, Wray, Elitza M, Deltcheva, Charlotta, Boiers, Simon Е, Richardson, Jyoti Bikram, Chhetri, John, Brown, Sladjana, Gagrica, Yanping, Guo, Anuradha, Illendula, Joost H A, Martens, Hendrik G, Stunnenberg, John H, Bushweller, Rachael, Nimmo, Tariq, Enver
Publikováno v:
Nature communications. 13(1)
The ETV6-RUNX1 onco-fusion arises in utero, initiating a clinically silent pre-leukemic state associated with the development of pediatric B-acute lymphoblastic leukemia (B-ALL). We characterize the ETV6-RUNX1 regulome by integrating chromatin immuno