Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jyoti B. Wadekar"'
Publikováno v:
Pharmaceutical Sciences, Vol 27, Iss 4, Pp 453-471 (2021)
Polo-like kinase 1(Plk1) plays an important role in the inhibition of cell proliferation and which is come under the family of serine/threonine-protein kinase. Which is a highly specific target for cancer therapy. In some clinical studies, Plk1 has b
Externí odkaz:
https://doaj.org/article/0a9f7fde490847278b7fe11ff030ad94
Publikováno v:
Journal of Chemistry, Vol 2013 (2013)
In continuation with our research program, in search of potent enzyme tyrosinase inhibitor, a series of synthesized 2,5-disubstituted 1,3,4-oxadiazoles have been evaluated for enzyme tyrosinase inhibitory activity. Subsequently, 3D QSAR and docking s
Externí odkaz:
https://doaj.org/article/19e4403f84e04cc880247d5a4b5b0702
Publikováno v:
Pharmaceutical Sciences, Vol 27, Iss 3, Pp 345-352 (2021)
Background: Cancer is a major cause of death all over the globe. Controlling cell division byinhibition of mitosis is the most successful clinical strategy for cancer treatment. The developmentof novel anticancer agents is the most important area in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7d0bf55a72cac9a6300dd9d7694cb93
https://ps.tbzmed.ac.ir/PDF/ps-27-345.pdf
https://ps.tbzmed.ac.ir/PDF/ps-27-345.pdf
Autor:
Anjali S. Rajbhoj, Rushikesh D. Ukirde, Ganesh D. Barkade, Manisha R. Sawant, Jyoti B. Wadekar, Ramesh L. Sawant
Background: Cancer is a leading cause of death worldwide. Inhibiting mitosis is the most effective clinical technique for cancer treatment. The most critical field of medicinal chemistry and drug development research is the discovery of innovative an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63ca3c6f19afd3eb63dd16c021a2233d
https://doi.org/10.21203/rs.3.rs-872668/v1
https://doi.org/10.21203/rs.3.rs-872668/v1
Publikováno v:
SSRN Electronic Journal.
Polo-like kinase 1 (Plk1) belongs to a subfamily of Ser/ Thr protein kinases, collectively termed polo-like kinases (Plks). A growing body of evidence suggests that Plk1 plays important roles during multiple stages of M-phase progression and, as a re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e6c9cf912ffe7a1db3f8503cf775465
https://doi.org/10.2139/ssrn.3534514
https://doi.org/10.2139/ssrn.3534514
Publikováno v:
The Journal of Phytopharmacology. 4:311-318
Rheumatoid Arthritis (RA) is a chronic autoimmune disease of unknown aetiology that affects 0.5% of the population and can result in disability owing to joint destruction, characterized by joint synovial inflammation and progressive cartilage and bon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8c7a095de6bf686e012e3e8dd072b9a
https://doi.org/10.31254/phyto.2015.4608
https://doi.org/10.31254/phyto.2015.4608
Autor:
Varsha R Raut, Ramesh L. Sawant, Kunal R Sanklecha, Amol S Ghodechor, Bhagyashri B More, Sachin V Kirtane, Jyoti B. Wadekar
Publikováno v:
The Journal of Phytopharmacology. 6:297-299
Dalbergia sissoo belonging to family Fabaceae is a widely growing plant and has been reported to possess multiple therapeutic properties like analgesic, anti-inflammatory, analgesic and antipyretic anti-ulcer, antioxidant, anthelmintic, antimicrobial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::237408f2a63d211371062d79f1f27c84
https://doi.org/10.31254/phyto.2017.6508
https://doi.org/10.31254/phyto.2017.6508
Publikováno v:
Journal of Chemistry, Vol 2013 (2013)
In continuation with our research program, in search of potent enzyme tyrosinase inhibitor, a series of synthesized 2,5-disubstituted 1,3,4-oxadiazoles have been evaluated for enzyme tyrosinase inhibitory activity. Subsequently, 3D QSAR and docking s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129d00262848028ea7c9129901e86976
https://doi.org/10.1155/2013/849782
https://doi.org/10.1155/2013/849782
Publikováno v:
Medicinal Chemistry Research. 22:1884-1892
Twenty-six different benzylidene oxazolo/thiazolo (3,2-a)-pyrimidine-6-carboxamide derivatives were synthesized and evaluated for their anti-inflammatory potential by protein denaturation method. The structures of title compounds were characterized b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::462f9e67130d583f9bb322e0d9ddb81c
https://doi.org/10.1007/s00044-012-0189-5
https://doi.org/10.1007/s00044-012-0189-5
Publikováno v:
Medicinal Chemistry Research. 21:1825-1832
A series of 2-methylthio-1,4-dihydropyrimidine derivatives (IIa–IIl) were synthesized in good yields by alkylation of 1,2,3,4-tetrahydropyrimidines (Ia–Il) with methyl iodide in the presence of pyridine. Their structures were confirmed by element
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7087e7f0b66dea3925fa0cd6b924e2b5
https://doi.org/10.1007/s00044-011-9700-7
https://doi.org/10.1007/s00044-011-9700-7