Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jyothsna Ravula"'
Autor:
Ramakrishna Nirogi, John Ieni, Vinod Kumar Goyal, Jyothsna Ravula, Satish Jetta, Anil Shinde, Pradeep Jayarajan, Vijay Benade, Veera Raghava Chowdary Palacharla, Dhanunjay Kumar Dogiparti, Venkat Jasti, Alireza Atri, Jeffrey Cummings
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction This study explored the efficacy and safety of a serotonin‐6 receptor antagonist, masupirdine, as adjunct treatment in patients with moderate Alzheimer's disease (AD) concomitantly treated with donepezil and memantine. Methods
Externí odkaz:
https://doaj.org/article/2946c8a2c70042bc98555d45982352fa
Autor:
Ramakrishna Nirogi, Vijay Benade, Vinod Kumar Goyal, Santosh Kumar Pandey, Abdul Rasheed Mohammed, Anil Shinde, Dhanunjay Dogiparti, Jyothsna Ravula, Satish Jetta, Veera Raghava Chowdary Palacharla
Publikováno v:
Clinical Drug Investigation. 42:747-762
Ropanicant hydrochloride (previously known as SUVN-911, hereinafter referred to as ropanicant) is a novel alpha4 beta2 nicotinic acetylcholine receptor (α4β2 nAchR) antagonist being developed for the treatment of major depressive disorder. The obje
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b0a8cb608da7795f4cc3a4b2fbb5b9
https://doi.org/10.1007/s40261-022-01189-9
https://doi.org/10.1007/s40261-022-01189-9
Autor:
Ramakrishna Nirogi, Pradeep Jayarajan, Vijay Benade, Anil Shinde, Vinod Kumar Goyal, Satish Jetta, Jyothsna Ravula, Renny Abraham, Venkata Ramalingayya Grandhi, Ramkumar Subramanian, Santosh Kumar Pandey, Rajesh Kumar Badange, Abdul Rasheed Mohammed, Venkat Jasti, Clive Ballard, Jeffrey Cummings
Publikováno v:
International Journal of Geriatric Psychiatry. 37
The effects of masupirdine on the neuropsychiatric symptoms were explored.Masupirdine (SUVN-502) was evaluated for its effects on cognition in patients with moderate AD. The prespecified primary outcome showed no drug-placebo difference. Post hoc ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9c1875b71599152ba90ab4d2f2a5e2b
https://doi.org/10.1002/gps.5813
https://doi.org/10.1002/gps.5813
Publikováno v:
AIP Conference Proceedings; 2023, Vol. 2548 Issue 1, p1-7, 7p
Autor:
Ramakrishna Nirogi, Vinod Kumar Goyal, Vijay Benade, Ramkumar Subramanian, Jyothsna Ravula, Satish Jetta, Anil Shinde, Santosh Kumar Pandey, Pradeep Jayarajan, Venkat Jasti, Jeffrey Cummings
Publikováno v:
Neurology and therapy. 11(4)
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive deterioration in cognition, memory and activities of daily living. Selective blockade of serotonin-6 (5-HTThe efficacy and safety of masupirdine were evaluated in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0516acbb5991d8def5c116e945f0b33
https://pubmed.ncbi.nlm.nih.gov/35908254
https://pubmed.ncbi.nlm.nih.gov/35908254
Autor:
Santosh Kumar Pandey, Vinod Kumar Goyal, Veera Raghava Chowdary Palacharla, Abdul Rasheed Mohammed, Gopinadh Bhyrapuneni, Satish Jetta, Nageswara Rao Muddana, Ramakrishna Nirogi, Jyothsna Ravula
Publikováno v:
Clinical Drug Investigation. 41:469-482
SUVN-D4010 is a novel, potent, highly selective 5-HT4 partial agonist intended for the treatment of cognitive disorders. The objective of the clinical study was to characterize the safety, tolerability, and pharmacokinetics of SUVN-D4010 in healthy a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af412d01403d5a9381d9223c5ca0f055
https://doi.org/10.1007/s40261-021-01027-4
https://doi.org/10.1007/s40261-021-01027-4
Autor:
Ramakrishna Nirogi, Jyothsna Ravula, Pradeep Jayarajan, Vinod Kumar Goyal, Satish Jetta, Anil Shinde, Vijay Benade
Publikováno v:
SLEEP. 46:A267-A267
Introduction Samelisant (SUVN-G3031) is a potent and selective histamine 3 receptor inverse agonist. In orexin knockout mice, samelisant produced wake-promoting and anticataplectic effects suggesting its potential therapeutic utility in the treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d058d50baa43cb2e2260bb84f0ca9be3
https://doi.org/10.1093/sleep/zsad077.0609
https://doi.org/10.1093/sleep/zsad077.0609
Autor:
Ramakrishna Nirogi, Pradeep Jayarajan, Jayaprakash Tadiparthi, Anil K Shinde, Mohammed Abdul Rasheed, Vinod Kumar Goyal, Gopinadh Bhyrapuneni, Vijay Benade, Veera Raghava Chowdary Palacharla, Jyothsna Ravula, Satish Jetta
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::417933192b2c4be3c999dee8815e8c25
https://doi.org/10.1002/alz.051571
https://doi.org/10.1002/alz.051571
Autor:
Ramakrishna, Nirogi, Gopinadh, Bhyrapuneni, Nageswara Rao, Muddana, Vinod Kumar, Goyal, Santosh Kumar, Pandey, Abdul Rasheed, Mohammed, Jyothsna, Ravula, Satish, Jetta, Veera Raghava Chowdary, Palacharla
Publikováno v:
Clinical drug investigation. 41(5)
SUVN-D4010 is a novel, potent, highly selective 5-HTSingle-ascending dose and multiple-ascending dose studies for 14 days were conducted in healthy adults using a randomized, double-blind design. The effects of food, sex, and age on SUVN-D4010 pharma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c8ae29d8088d7e59a596c8df167bfc57
https://pubmed.ncbi.nlm.nih.gov/33788154
https://pubmed.ncbi.nlm.nih.gov/33788154
Autor:
Ramakrishna Nirogi, Jyothsna Ravula, Pradeep Jayarajan, Vinod Kumar Goyal, Satish Jetta, Anil Shinde, Vijay Benade, Venkat Jasti
Publikováno v:
Sleep. 45:A274-A274
Introduction Histamine H3 receptor (H3R) antagonists/inverse agonists increase histaminergic neurotransmission and offer a therapeutic option for the treatment of narcolepsy. Samelisant (SUVN-G3031) is a potent H3R inverse agonist and exhibits very h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::884fe145d0a12bb7115e6752763cf380
https://doi.org/10.1093/sleep/zsac079.621
https://doi.org/10.1093/sleep/zsac079.621