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pro vyhledávání: '"Jyothi Subramanian"'
Autor:
Bhanu Duggal, Jyothi Subramanian, Mona Duggal, Pushpendra Singh, Meeta Rajivlochan, Sujata Saunik, Koundinya Desiraju, Archana Avhad, Usha Ram, Sayan Sen, Anurag Agrawal
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196830 (2018)
A prospective, multicenter study was initiated by the Government of Maharashtra, India, to determine predictors of long-term outcomes of percutaneous coronary intervention (PCI) for coronary artery disease, and to compare the effectiveness of drug-el
Externí odkaz:
https://doaj.org/article/33fbeac7c0a94f75a1816b7b9fb984a1
Akademický článek
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Autor:
Li Chen, Rodrigo F. Chuaqui, Sarah B. Miller, Jyothi Subramanian, Larry Rubinstein, Robert J. Kinders, Andrea Regier Voth, Scott M. Lawrence, Apurva K. Srivastava, Tony Navas, Melinda G. Hollingshead, Shivaani Kummar, Hala R. Makhlouf, Katherine V. Ferry-Galow, James H. Doroshow, Ralph E. Parchment, Alice P. Chen, Deborah Wilsker, Mariam M. Konaté, Sergio Y. Alcoser, Suzanne Borgel, Tomas Vilimas, Donald P. Bottaro
Publikováno v:
Cancer Res
The significance of the phenotypic plasticity afforded by epithelial–mesenchymal transition (EMT) for cancer progression and drug resistance remains to be fully elucidated in the clinic. We evaluated epithelial–mesenchymal phenotypic characterist
Autor:
Archana Avhad, Pushpendra Singh, Bhanu Duggal, Meeta Rajivlochan, Jyothi Subramanian, Anurag Agrawal, Mona Duggal, Sujata Saunik, Sayan Sen, Koundinya Desiraju, Usha Ram
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196830 (2018)
PLoS ONE
PLoS ONE
A prospective, multicenter study was initiated by the Government of Maharashtra, India, to determine predictors of long-term outcomes of percutaneous coronary intervention (PCI) for coronary artery disease, and to compare the effectiveness of drug-el
Autor:
Jyothi Subramanian, Richard Simon
Publikováno v:
Contemporary Clinical Trials. 36:636-641
The growing recognition that human diseases are molecularly heterogeneous has stimulated interest in the development of prognostic and predictive classifiers for patient selection and stratification. In the process of classifier development, it has b
Autor:
Jyothi Subramanian, Richard Simon
Publikováno v:
Statistics in Medicine. 30:642-653
Resampling techniques are often used to provide an initial assessment of accuracy for prognostic prediction models developed using high-dimensional genomic data with binary outcomes. Risk prediction is most important, however, in medical applications
Autor:
Jyothi Subramanian, Richard Simon
Publikováno v:
Nature Reviews Clinical Oncology. 7:327-334
Well-developed and validated genomic signatures can lead to personalized treatment decisions resulting in improved patient management. However, the pace of acceptance of these signatures in clinical practice has been slow because many of the signatur
Publikováno v:
Drug Discovery Today. 14:394-400
Docking, virtual screening and structure-based drug design are routinely used in modern drug discovery programs. Although current docking methods deal with flexible ligands, managing receptor flexibility has proved to be challenging. In this brief re
Publikováno v:
ChemMedChem. 3:336-344
Receptor rearrangement upon ligand binding (induced fit) is a major stumbling block in docking and virtual screening. Even though numerous studies have stressed the importance of including protein flexibility in ligand docking, currently available me
Autor:
Jyothi Subramanian, Richard Simon
Publikováno v:
Proceedings of the Fourth Seattle Symposium in Biostatistics: Clinical Trials ISBN: 9781461452447
Developments in genomics are providing a biological basis for the heterogeneity of clinical course and response to treatment that have long been apparent to clinicians. The ability to molecularly characterize human diseases presents new opportunities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a6f5ad952555dbe15697ae27a09d837
https://doi.org/10.1007/978-1-4614-5245-4_5
https://doi.org/10.1007/978-1-4614-5245-4_5