Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Jyothi Prasanna"'
Publikováno v:
Regenerative Therapy, Vol 26, Iss , Pp 89-101 (2024)
Introduction: Immunomodulation is the predominant mechanism via which Mesenchymal stromal cells (MSCs) mediate their therapeutic benefits. However, inconsistent success in numerous clinical trials warrants a better understating of the molecular mecha
Externí odkaz:
https://doaj.org/article/a5462a71fc37428fa585a1f058929555
Autor:
Meenal Francis, Smitha Bhaskar, Saarwani Komanduri, Preethi Sheshadri, Jyothi Prasanna, Anujith Kumar
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106771- (2023)
Summary: Loss of insulin-secreting β-cells in diabetes may be either due to apoptosis or dedifferentiation of β-cell mass. The ubiquitin-proteasome system comprising E3 ligase and deubiquitinases (DUBs) controls several aspects of β-cell functions
Externí odkaz:
https://doaj.org/article/e4bf2c1186704b0691f263f5a0c93098
Autor:
Smitha Bhaskar, Preethi Sheshadri, Joel P. Joseph, Chandrakanta Potdar, Jyothi Prasanna, Anujith Kumar
Publikováno v:
iScience, Vol 23, Iss 10, Pp 101564- (2020)
Summary: Studies revealing molecular mechanisms underlying neural specification have majorly focused on the role played by different transcription factors, but less on non-nuclear components. Earlier, we reported mitochondrial superoxide dismutase (S
Externí odkaz:
https://doaj.org/article/f68df843cc594b26ad55106118bffd38
Autor:
Samatha Bhat, Pachaiyappan Viswanathan, Shashank Chandanala, S. Jyothi Prasanna, Raviraja N. Seetharam
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Bone marrow-derived mesenchymal stromal cells (BM-MSCs) are gaining increasing importance in the field of regenerative medicine. Although therapeutic value of MSCs is now being established through many clinical trials, issues have been raise
Externí odkaz:
https://doaj.org/article/507e5f051ff34c1ba30abd9f3c42903b
Autor:
Vaishali Garg, Shashank Chandanala, M. David-Luther, M. Govind, Roshni Ravi Prasad, Anujith Kumar, S. Jyothi Prasanna
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The impact of immune system and inflammation on organ homeostasis and tissue stem cell niches in the absence of pathogen invasion has long remained a conundrum in the field of regenerative medicine. The paradoxical role of immune components in promot
Externí odkaz:
https://doaj.org/article/5f7abb66edd547488f01d99d7266db77
Publikováno v:
Current Protein & Peptide Science. 23:602-618
Abstract: Impairment in the function of insulin-producing pancreatic β-cells is a hallmark of both type 1 and 2 diabetes (T1D/T2D). Despite over a century of effort, there is still no precise treatment regimen available for acute diabetes. Enhancing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af8eef0e982f39e32e3c148da2d7ab1
https://doi.org/10.2174/1389203723666220422092023
https://doi.org/10.2174/1389203723666220422092023
Autor:
Smitha Bhaskar, Jeevan Gowda, Akshay Hegde, Surya Chandra Rao Thumu, Narendrakumar Ramanan, Jyothi Prasanna, Anujith Kumar
Dopaminergic (DA) neurons in the Olfactory bulb (OB) are involved in odor detection and discrimination. Transcription factor (TF) regulatory network responsible for their fate specification remains poorly understood and the spatial regulation of DA n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b964fef79ee1e2d00e30a9d66fac7413
https://doi.org/10.1101/2022.10.30.514394
https://doi.org/10.1101/2022.10.30.514394
Diabetes is a metabolic disease caused majorly due to loss of insulin secreting β-cells. Along with apoptosis, recent reports revealed dedifferentiation to be the added reason for the reduced β-cell mass. The Ubiquitin Proteasome system comprising
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc83f12a313979d3bae2349186a45b65
https://doi.org/10.1101/2022.10.14.512247
https://doi.org/10.1101/2022.10.14.512247
Autor:
Anujith Kumar, Meenal Francis, Akshaya Ashok, Ashwini Ashwathnarayan, Shreetama Banerjee, Jyothi Prasanna
Publikováno v:
Current diabetes reviews.
Abstract: Distinct molecular processes are engaged during histogenesis, and Epithelial to Mesenchymal Transition (EMT) is one of the key evolutionarily conserved processes that facilitates organ development. Molecular pathways governing EMT are embed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a7ebdc8f3df42b00c4b12ac2a4f02a
https://pubmed.ncbi.nlm.nih.gov/35598235
https://pubmed.ncbi.nlm.nih.gov/35598235
Autor:
Sowmya, Jahnavi, Vaishali, Garg, Anoop Babu, Vasandan, Swathi, SundarRaj, Anujith, Kumar, Jyothi, Prasanna S
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 149:106256
Pluripotent stem cell derived-hepatocytes depict fetal -hepatocyte characteristics/maturity and are immunogenic limiting their applications. Attempts have been made to derive hepatocytes from mesenchymal stem cells using developmental cocktails, epig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5177ef6640675229479d64f01ad4245d
https://doi.org/10.1016/j.biocel.2022.106256
https://doi.org/10.1016/j.biocel.2022.106256