Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jyoji Okuda"'
Autor:
Jyoji Okuda, Mariko Itsubo, Masaki Hara, Atsushi Hokari, Tomonobu Kawabe, Masami Sakaguchi, Gotarou Toda, Kazuhiko Koike, Yasushi Okuaki, Yasuyuki Enomoto
Publikováno v:
Kanzo. 37:36-41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d74293516127731a97f755bb219fafb
https://doi.org/10.2957/kanzo.37.36
https://doi.org/10.2957/kanzo.37.36
Publikováno v:
Endocrine Journal. 43:197-204
In order to determine what and how many test items are necessary for the initial tests when examining patients with thyroid disorders, a questionnaire was sent to the council members of the Japan Thyroid Association. Thyroid disorders were divided in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a99cdcbb299e584e2802746f4cbbb7b3
https://doi.org/10.1507/endocrj.43.197
https://doi.org/10.1507/endocrj.43.197
Autor:
Chizuko Ohta, Takashi Akamizu, Jyoji Okuda, Y. Kiho, Hideo Sugawa, Yoshihiro Ueda, Tomohiko Mori, Shinji Kosugi
Publikováno v:
Journal of Endocrinological Investigation. 18:710-717
In this study, we apply recently developed methods to evaluate the thyrotropin receptor (TSH-R). These methods are called deviation (DEV) model, deviation decrease (DD) and DEV/DD analyses, and are based on deviation of amino acid sequences. A 3-dime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a746be1f1cbfc06d6ab97b848ac239b
https://doi.org/10.1007/bf03349793
https://doi.org/10.1007/bf03349793
Autor:
Fumihiko Matsuda, Jyoji Okuda, Hua Li, Toru Mori, Hideo Sugawa, Takeshi Tsubata, Takashi Akamizu
Publikováno v:
Biochemical and Biophysical Research Communications. 207:985-993
In autoimmune diseases, IgG class autoantibodies are generally considered to be more pathognomonic than IgM class ones. Although Epstein-Barr virus (EBV)-transformation of lymphocytes is a useful method to obtain human monoclonal autoantibodies, it t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c8f6856365efd9943f957ef3fcb3f1
https://doi.org/10.1006/bbrc.1995.1282
https://doi.org/10.1006/bbrc.1995.1282
Autor:
Takashi Akamizu, Jyoji Okuda, Yoshimichi Ueda, Yukio Kihou, Michiko Ueda, Toru Mori, Shinji Kosugi, Hideo Sugawa, Chizuko Ohta
Publikováno v:
European Journal of Endocrinology. 132:62-68
Ueda Y, Sugawa H, Akamizu T, Okuda J, Ueda M, Kosugi S, Ohta C, Kihou Y, Mori T. Thyroidstimulating antibodies in sera from patients with Graves' disease are heterogeneous in epitope recognition. Eur J Endocrinol 1995;132:62–8. ISSN 0804–4643 Two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ef45e952bd2085e849d0fc326e5e009
https://doi.org/10.1530/eje.0.1320062
https://doi.org/10.1530/eje.0.1320062
Publikováno v:
Endocrine Journal. 42:697-704
We treated a patient who was hyperthyroid due to Graves' disease and strongly resistant to methimazole (MMI): in spite of good compliance, she needed 150 mg of MMI daily to control her hyperthyroidism. To elucidate the reasons of resistance to MMI, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78cff62c10f5ef893e20fbd91060fbe3
https://doi.org/10.1507/endocrj.42.697
https://doi.org/10.1507/endocrj.42.697
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 79:1600-1604
Anti-TSH receptor antibodies (TSH-R Ab), which have been detected in the serum of some patients with primary myxedema, are themselves considered to induce hypothyroidism. These are termed blocking-type TSH-R Ab (TSH-R BAb), because they inhibit adeny
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae677548b2fa455885102320b95aaad5
https://doi.org/10.1210/jcem.79.6.7989462
https://doi.org/10.1210/jcem.79.6.7989462
Autor:
Hideo Sugawa, Jyoji Okuda, Takashi Akamizu, Daisuke Inoue, Shinji Kosugi, Toru Mori, Yoshimichi Ueda
Publikováno v:
Endocrine Journal. 41:1-11
Recent progress in the studies of epitope analysis of the TSH-R against TSH-R Ab was reviewed extensively. Using both site-directed mutagenesis and synthetic TSH-R peptide, binding and/or action sites of TSH-R Ab have been known to be multiple and di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05742a0e7cb17119332f5143c35ac7b3
https://doi.org/10.1507/endocrj.41.1
https://doi.org/10.1507/endocrj.41.1
Autor:
Naotetsu Kanamoto, Takashi Akamizu, Yuji Hataya, Yoshiyuki Hattori, Tomohiko Mori, Kenji Moriyama, Fumihiko Matsuda, Kazuwa Nakao, Misa Saijo, Jyoji Okuda
Publikováno v:
Journal of endocrinological investigation. 26(11)
Anti-TSH receptor antibodies (TRAbs) have been known to be involved in Graves’ disease and primary hypothyroidism. We previously isolated and reconstituted immunoglobulin (Ig) genes of Epstein-Barr virus-transformed B cell clones producing monoclon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196f49697b8b5b0c063d338d727f233b
https://pubmed.ncbi.nlm.nih.gov/15008244
https://pubmed.ncbi.nlm.nih.gov/15008244
Publikováno v:
Thyroid : official journal of the American Thyroid Association. 5(4)
From the peripheral lymphocytes of a patient with Graves' disease, we established a T cell line using its reaction to a pool of 49 synthetic peptides corresponding to the entire human thyrotropin receptor (TSHR) sequence. This T cell line showed a sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::716c93f81211e10b45cfa6fd3ad50c55
https://pubmed.ncbi.nlm.nih.gov/7488865
https://pubmed.ncbi.nlm.nih.gov/7488865