Výsledky vyhledávání - "Jye Swei Guan"

Supplementary Methods from Elevated WBP2 Expression in HER2-positive Breast Cancers Correlates with Sensitivity to Trastuzumab-based Neoadjuvant Therapy: A Retrospective and Multicentric Study

Autor: Yoon Pin Lim, Soo Chin Lee, Swee Ho Lim, Joohyuk Sohn, Thomas Choudary Putti, Mihir Gudi, Puay Hoon Tan, Chow Yin Wong, Joaquín Arribas, Cristina Bernadó, Aye Aye Thike, Tinghine Chu, Hock Jin Tan, Jye Swei Guan, Shin-Ae Kang

Supplementary Methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ebe0e5ed219304213c8ae3906103551
https://doi.org/10.1158/1078-0432.22472631.v1

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Supplementary Table 1 from Elevated WBP2 Expression in HER2-positive Breast Cancers Correlates with Sensitivity to Trastuzumab-based Neoadjuvant Therapy: A Retrospective and Multicentric Study

Supplementary Table 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba4884e9f2678d03745abd1a52f9724
https://doi.org/10.1158/1078-0432.22472628.v1

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Supplementary Figure from Elevated WBP2 Expression in HER2-positive Breast Cancers Correlates with Sensitivity to Trastuzumab-based Neoadjuvant Therapy: A Retrospective and Multicentric Study

Supplementary Figure 1 and 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0002ca507f66a20d45d6f8646d074092
https://doi.org/10.1158/1078-0432.22472634.v1

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Data from Elevated WBP2 Expression in HER2-positive Breast Cancers Correlates with Sensitivity to Trastuzumab-based Neoadjuvant Therapy: A Retrospective and Multicentric Study

Purpose:Trastuzumab-based chemotherapy has shown remarkable clinical benefits for patients with HER2-positive breast cancer. However, treatment regimens involving trastuzumab had little or no effect for a subset of patients. Preliminary studies revea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1283db3cc1a578f5278791713fbddf6d
https://doi.org/10.1158/1078-0432.c.6528279.v1

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Wnt Signaling Promotes Breast Cancer by Blocking ITCH-Mediated Degradation of YAP/TAZ Transcriptional Coactivator WBP2

Autor: Yoon Pin Lim, Puay Hoon Tan, Shen Kiat Lim, Siew Wee Chan, Shin Ae Kang, Aye Aye Thike, Marius Sudol, Hock Jin Tan, Zilin Li, Jye Swei Guan, Wanjin Hong, Thomas Choudary Putti, Zhen Ning Adrian Wee, J. Sivaraman, Vishnu Priyanka Reddy Chichili, Ssu Yi Lu, David M. Virshup

Publikováno v: Cancer Research. 76:6278-6289

Cross-talk between the Hippo and Wnt pathways has been implicated recently in breast cancer development, but key intersections have yet to be fully defined. Here we report that WBP2, a transcription coactivator that binds the Hippo pathway transcript

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bcfee48186c70a6bfd4e89d80b4bff4
https://doi.org/10.1158/0008-5472.can-15-3537

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Elevated WBP2 Expression in HER2-positive Breast Cancers Correlates with Sensitivity to Trastuzumab-based Neoadjuvant Therapy: A Retrospective and Multicentric Study

Autor: Swee Ho Lim, Soo-Chin Lee, Mihir Gudi, Yoon Pin Lim, Thomas C. Putti, Tinghine Chu, Chow Yin Wong, Joohyuk Sohn, Puay Hoon Tan, Hock Jin Tan, Shin Ae Kang, Aye Aye Thike, Cristina Bernadó, Joaquín Arribas, Jye Swei Guan

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 25(8)

Purpose: Trastuzumab-based chemotherapy has shown remarkable clinical benefits for patients with HER2-positive breast cancer. However, treatment regimens involving trastuzumab had little or no effect for a subset of patients. Preliminary studies reve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebea61a2ba5403953adc4118a67979a7
https://pubmed.ncbi.nlm.nih.gov/30593516

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Divide and conquer: subproteomic approaches toward gastric cancer biomarker and drug target discovery

Autor: Hock Jin Tan, Fan Lin, Yoon Pin Lim, Jye Swei Guan

Publikováno v: Expert Review of Proteomics. 11:515-530

The discovery of biomarkers for early detection and treatment for gastric cancer are two important gaps that proteomics have the potential to fill. Advancements in mass spectrometry, sample preparation and separation strategies are crucial to proteom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d7c40b4f892ca7130e630083b32b46
https://doi.org/10.1586/14789450.2014.904751

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A novel NOD1- and CagA-independent pathway of interleukin-8 induction mediated by theHelicobacter pyloritype IV secretion system

Autor: Rebecca J. Gorrell, Yue Xin, Jye Swei Guan, Mona Tafreshi, Richard L. Ferrero, Michael A. McGuckin, Terry Kwok, Melanie L. Hutton

Publikováno v: Cellular Microbiology. 15:554-570

The type IV secretion system (T4SS) of Helicobacter pylori triggers massive inflammatory responses during gastric infection by mechanisms that are poorly understood. Here we provide evidence for a novel pathway by which the T4SS structural component,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4176f41f89135637f9dba78b68719b8e
https://doi.org/10.1111/cmi.12055

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