Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jyan-Gwo J. Su"'
Autor:
Wen-Cheng Chu, Wen-Feng Hsiao, Shin-Chang Lin, Mou-Tsy Chou, Wei-Fu Hong, See-Chang Huang, Min-Cong Huang, Jin-Yi Wu, Jyan-Gwo J. Su, Wen-Je Liu, Yi-Wen Liu, Fei-Yun Chen
Publikováno v:
Toxicology Letters. 192:252-260
1,10-phenanthroline (phen), flufenamic acid, and indomethacin are inhibitors of aldo-keto reductases 1C1 (AKR1C1), but only phen decreased the benzo[a]pyrene (BaP)-induced cytochrome P450 1a1 (Cyp1a1) protein level. Therefore the decrease in the BaP-
Autor:
Fei-Yun Chen, Wei-Fu Hong, Wen-Cheng Chu, Pei-Jyuan Liao, Jyan-Gwo J. Su, Min-Cong Huang, Shin-Chang Lin
Publikováno v:
Chemical Research in Toxicology. 22:1938-1947
Cytochrome P450 1a1 (Cyp1a1) is a phase I xenobiotic-metabolizing enzyme, the expression of which is mainly driven by the aryl hydrocarbon receptor (AhR). Cyp1a1 messenger (m)RNA is labile. Our study indicates that 1-nitropyrene (1-NP) highly induced
Autor:
Qwa-Fun Wang, Ke-Yu Chen, Ming-Ho Chen, Shu-Hsin Chen, Jia-Jen Shee, Jung-Chou Chen, Yi-Wen Liu, Lih Geeng Chen, Jyan-Gwo J. Su
Publikováno v:
Journal of Ethnopharmacology. 126:42-49
Aim of the study Gynostemma pentaphyllum is a popular folk medicine that has been used for treatment of hepatitis in Asia. Our previous study demonstrates that Gynostemma pentaphyllum n-butanol extract inhibits the onset and improves the recovery of
Autor:
Shao-Hung Wang, Chu-Ting Liang, Jyan-Gwo J. Su, See-Chang Huang, Wei-Fu Hong, Yi-Wen Liu, Min-Cong Huang
Publikováno v:
Toxicology. 262:87-97
Pyrene, benzo[a]pyrene (BaP), and indeno[1,2,3-cd]pyrene (IND) are poly cyclic aromatic hydrocarbons (PAHs) with four to six annealed phenyl rings. Dexamethasone (Dex) is a synthetic agonist of glucocorticoids. The aryl hydrocarbon receptor (AhR) lig
Autor:
Ilpo Huhtaniemi, Talal El-Hefnawy, Fu-Ping Zhang, Aaron J. W. Hsueh, Jyan-Gwo J. Su, Kirsi Kananen, Merja Markkula, Tommi Paukku
Publikováno v:
Molecular and Cellular Endocrinology. 119:135-146
Testicular tumorigenesis was observed in transgenic mice expressing the 6-kb mouse inhibin α-subnit promoter/Simian virus 40 T-antigen (SV40 Tag) fusion gene. The tumors were confined to Leydig cells using immunohistochemistry with anti-Tag antibody
Publikováno v:
Nature. 360:313-319
The inhibins are alpha:beta heterodimeric growth factors that are members of the transforming growth factor-beta family. To understand the physiological roles of the inhibins in mammalian development and reproduction, a targeted deletion of the alpha
Publikováno v:
Toxicology. 244(2-3)
It is reported that diesel exhaust particles contain more 1-nitropyrene (1-NP) than benzo[a]pyrene (B[a]P), both of which are potent carcinogenic compounds. In this study, we show that 1-NP is more potent in reducing cell viability than B[a]P, pyrene
Publikováno v:
Molecular and biochemical parasitology. 66(1)
Schistosoma mansoni, a human parasitic worm, depends on anaerobic glycolysis as the main source of energy. Phosphofructokinase (ATP: D-fructose-6-phosphate 1-phosphotransferase, EC 2.7.1.11; PFK) limits the rate of glycolysis in these organisms and i
Autor:
Wen-Cheng Chu, Wei-Fu Hong, Min-Cong Huang, Fei-Yun Chen, Shin-Chang Lin, Pei-Jyuan Liao, Jyan-Gwo J. Su
Publikováno v:
Chemical Research in Toxicology; Dec2009, Vol. 22 Issue 12, p1938-1947, 10p