Abstract P2-06-03: Insulin receptor isoform signaling in breast cancer

Autor: C Dong, Jy Chan, Y Pan, X Zhang, D Yee

Publikováno v: Cancer Research. 79:P2-06

Recent data shows that insulin receptor (IR) and the type I insulin-like growth factor receptor (IGF1R) play important roles in breast cancer cell biology. Targeting only IGF1R has not been successful perhaps due to compensation by IR. IR exists in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0902df51c13b6c894f2e3d933e2fa1da
https://doi.org/10.1158/1538-7445.sabcs18-p2-06-03

Functionally defined CD164 epitopes are expressed on CD34(+) cells throughout ontogeny but display distinct distribution patterns in adult hematopoietic and nonhematopoietic tissues

Autor: Sm, Watt, Lh, Butler, Tavian M, Hj, Bühring, Rappold I, Pj, Simmons, Ac, Zannettino, Buck D, Fuchs A, Regis Doyonnas, Jy, Chan, Jp, Levesque, Peault B, Roxanis I

Publikováno v: Europe PubMed Central

Three distinct classes of epitopes on human CD164 have been identified. Two of these, recognized by the monoclonal antibodies 105A5 and 103B2/9E10, are the CD164 class I and class II functionally defined epitopes, which cooperate to regulate adhesion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::37aa9552dadfb07c3afc5535460f5b31
https://pubmed.ncbi.nlm.nih.gov/10807777

Conservative management of postoperative chylous fistula with octreotide and peripheral total parenteral nutrition

Autor: Jy, Chan, Ew, Wong, Sk, Ng, Ca, Hasselt, Alexander Vlantis

Publikováno v: Europe PubMed Central

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f05927f6450cdf03d1d542571d1aecb3
http://europepmc.org/abstract/med/28719710

CDC7 Inhibition Potentiates Antitumor Efficacy of PARP Inhibitor in Advanced Ovarian Cancer.

Autor: Liu S; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, 510060, P. R. China.; Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, Southern Medical University, Guangzhou, Guangdong, 510080, P. R. China., Deng P; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, 510060, P. R. China.; Biotherapy Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, P. R. China., Yu Z; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510655, P. R. China., Hong JH; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore., Gao J; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, 510060, P. R. China., Huang Y; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, 510060, P. R. China., Xiao R; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, 510060, P. R. China., Yin J; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, 510060, P. R. China., Zeng X; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, 510060, P. R. China., Sun Y; Department of Laboratory Medicine, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, 510180, P. R. China., Wang P; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, 510060, P. R. China., Geng R; Experimental Animal Center, Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, 511436, P. R. China., Chan JY; Division of Medical Sciences, Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore, 169610, Singapore., Guan P; Genome Institute of Singapore, A*STAR, Singapore, 138672, Singapore., Yu Q; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore.; Genome Institute of Singapore, A*STAR, Singapore, 138672, Singapore., Teh BT; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore.; Division of Medical Sciences, Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore, 169610, Singapore.; Genome Institute of Singapore, A*STAR, Singapore, 138672, Singapore., Jiang Q; Department of Patholgy, Guangdong Provincial Key Laboratory of Major Obstetric Disease, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510150, China., Xia X; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, 510060, P. R. China., Xiong Y; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, 510060, P. R. China., Chen J; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, 510060, P. R. China., Huo Y; Experimental Animal Center, Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, 511436, P. R. China., Tan J; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, 510060, P. R. China.; Division of Medical Sciences, Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore, 169610, Singapore.; Hainan Academy of Medical Science, Hainan Medical University, Haikou, 571199, P. R. China.

Publikováno v: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Oct 16, pp. e2403782. Date of Electronic Publication: 2024 Oct 16.

Aristolochic acid-related renal cell carcinoma exhibits a distinct tumor-immune microenvironment favoring response to immune checkpoint blockade.

Autor: Lin PH; Division of Urology, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Graduate Institute of Clinical Medical Science, College of Medicine, Chang Gung University, Taoyuan, Taiwan.; School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan., Chan JY; Cancer Discovery Hub, National Cancer Centre Singapore, Singapore, Singapore., Guan P; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Hong JH; Cancer and Stem Cell Biology Programme, Duke-NUS Medical School, Singapore, Singapore., Lim AH; Cancer Discovery Hub, National Cancer Centre Singapore, Singapore, Singapore., Ng CC; Cancer Discovery Hub, National Cancer Centre Singapore, Singapore, Singapore., Yeong JPS; Integrative Biology for Theranostics Lab, Cancer Signaling & Therapies Programme, Institute of Molecular and Cell Biology, Singapore, Singapore.; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore.; Pathology Academic Clinical Program, Duke-NUS Medical School, Singapore, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Lee JY; Cancer Discovery Hub, National Cancer Centre Singapore, Singapore, Singapore., Liu W; Laboratory of Cancer Epigenome, Division of Medical Science, National Cancer Centre Singapore, Singapore, Singapore., Lim JCT; Integrative Biology for Theranostics Lab, Cancer Signaling & Therapies Programme, Institute of Molecular and Cell Biology, Singapore, Singapore., Pang ST; Division of Urology, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan., Teh BT; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Cancer and Stem Cell Biology Programme, Duke-NUS Medical School, Singapore, Singapore.; Laboratory of Cancer Epigenome, Division of Medical Science, National Cancer Centre Singapore, Singapore, Singapore.; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.

Publikováno v: The Journal of pathology [J Pathol] 2024 Oct 03. Date of Electronic Publication: 2024 Oct 03.