Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Jwu‐Lai Yeh"'
Autor:
Yi‐Ching Liu, Yu‐Hsin Tseng, Yu‐Hsin Kuan, Lin‐Yen Wang, Shang‐En Huang, Siao‐Ping Tsai, Jwu‐Lai Yeh, Jong‐Hau Hsu
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 6, Pp 542-552 (2024)
Abstract Pulmonary vascular remodeling is a key pathological process of pulmonary arterial hypertension (PAH), characterized by uncontrolled proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs). Bortezomib (BTZ) is the first
Externí odkaz:
https://doaj.org/article/557d4f3df00944bfa7f064f5837c65fb
Autor:
Yi-Chia Wu, Wei-Ting Wang, Ming-Chun Yang, Yu-Tsun Su, Jwu-Lai Yeh, Jong-Hau Hsu, Jiunn-Ren Wu
Publikováno v:
Biological Research, Vol 56, Iss 1, Pp 1-16 (2023)
Abstract Background Abnormal remodeling of the pulmonary vasculature, characterized by the proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs) along with dysregulated glycolysis, is a pathognomonic feature of pulmonary arte
Externí odkaz:
https://doaj.org/article/cc7bb2c564ff45e18571fe0ff1d3f604
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 440 (2024)
Exposure to hypoxia results in the development of pulmonary arterial hypertension (PAH). An increase in the intracellular Ca2+ concentration ([Ca2+]i) in pulmonary artery smooth muscle cells (PASMCs) is a major trigger for pulmonary vasoconstriction
Externí odkaz:
https://doaj.org/article/01ded0fe5abd44bfbe6d191ec1743384
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 115109- (2023)
Retinal neovascularization (RNV) and cell apoptosis observed in retinopathy are the most common cause of vision loss worldwide. Increasing vascular endothelial growth factor (VEGF), which was driven by hypoxia or inflammation, would result in RNV. Th
Externí odkaz:
https://doaj.org/article/3725a8b14f91465984c4d1f7b31108b5
Autor:
Cheng-Hsiang Kuo, Ban-Hua Zhang, Shang-En Huang, Jong-Hau Hsu, Yan-Hsiung Wang, Thi Tuyet Ngan Nguyen, Chao-Han Lai, Jwu-Lai Yeh
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Periodontitis is an inflammatory disease of gum that may predispose to serious systemic complications such as diabetes and cardiovascular diseases. Activation of macrophages and osteoclasts around periodontal tissue can accelerate gum inflammation. I
Externí odkaz:
https://doaj.org/article/1106d2782d1a423cbe46ff7b4dbe2b46
Autor:
Erna Sulistyowati, Ren-Long Jan, Shu-Fen Liou, Ying-Fu Chen, Bin-Nan Wu, Jong-Hau Hsu, Jwu-Lai Yeh
Publikováno v:
Journal of Traditional and Complementary Medicine, Vol 10, Iss 4, Pp 378-388 (2020)
Background and aim: Centella asiatica, Justicia gendarussa and Imperata cylindrica decoction (CJID) is efficacious for hypertension. NADPH (nicotinamide adenine dinucleotide phosphate) oxidase (NOX)-induced reactive oxygen species (ROS) generation mo
Externí odkaz:
https://doaj.org/article/67b2f732960a4277a4e008dd475bfe12
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Closure of the ductus arteriosus (DA) involves vasoconstriction and vascular remodeling. Cinaciguat, a soluble guanylyl cyclase (sGC) activator, was reported with vasodilatory and anti-remodeling effects on pulmonary hypertensive vessels. However, it
Externí odkaz:
https://doaj.org/article/a508a5fd03a546dd98e20f92091e65cb
Publikováno v:
Medicina, Vol 58, Iss 7, p 879 (2022)
Background and objectives: Traditional Chinese medicines (TCMs) are widely prescribed to relieve ischemic heart disease (IHD); however, no cohort studies have been conducted on the use of TCMs for patients with IHD. The aim of the study was to analyz
Externí odkaz:
https://doaj.org/article/c0df83bc06ed4f7c8ad6c76a40cca16a
Autor:
Meng-Chien Willie Hsieh, Wei-Ting Wang, Jwu-Lai Yeh, Chuang-Yu Lin, Yur-Ren Kuo, Su-Shin Lee, Ming-Feng Hou, Yi-Chia Wu
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1415 (2022)
Pulmonary arterial hypertension (PAH) is a rare yet serious progressive disorder that is currently incurable. This female-predominant disease unfolds as a pan-vasculopathy that affects all layers of the vessel wall. Five classes of pharmacological ag
Externí odkaz:
https://doaj.org/article/6064ea0dcf4340cd84b2403317792825
Autor:
I-Chen Chen, Jao-Yu Lin, Yi-Ching Liu, Chee-Yin Chai, Jwu-Lai Yeh, Jong-Hau Hsu, Bin-Nan Wu, Zen-Kong Dai
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background: Pulmonary arterial hypertension (PAH) is a life-threatening and deteriorating disease with no promising therapy available currently due to its diversity and complexity. An imbalance between vasoconstriction and vasodilation has been propo
Externí odkaz:
https://doaj.org/article/f951dc7f8907482d96befeaf43034ebe