Zobrazeno 1 - 10
of 271
pro vyhledávání: '"Jw, Kappler"'
Publikováno v:
Europe PubMed Central
It has previously been demonstrated that mature mouse T cells live for many weeks in vivo. In contrast, explanted lymph node or splenic T cells undergo spontaneous death within days, suggesting that survival factors supplied in vivo are not present i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::261409afa33c7c62b8db9c09d9c57d87
https://pubmed.ncbi.nlm.nih.gov/9190930
https://pubmed.ncbi.nlm.nih.gov/9190930
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c4f97f2dc87886255d6b38e1830b975b
https://pubmed.ncbi.nlm.nih.gov/1835261
https://pubmed.ncbi.nlm.nih.gov/1835261
Publikováno v:
Europe PubMed Central
The Staphylococcus aureus enterotoxins are known to be potent T cell activators, stimulating cell proliferation and lymphokine production. Two additional S. aureus proteins, exfoliating toxin and toxic shock syndrome toxin, share these properties. Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d4345fadc55d7518dc225c022a8d830c
https://pubmed.ncbi.nlm.nih.gov/2138648
https://pubmed.ncbi.nlm.nih.gov/2138648
Autor:
Philippa Marrack, Jw, Kappler
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f574e25e96437e81dcf847eed1f96ed5
https://pubmed.ncbi.nlm.nih.gov/2190587
https://pubmed.ncbi.nlm.nih.gov/2190587
Publikováno v:
Europe PubMed Central
A 17-amino acid tryptic peptide of chicken ovalbumin, designated P323-339, that substituted for processed antigen when presented by glutaraldehyde prefixed accessory cells to specific I-restricted T hybridomas was characterized. The peptide antigen c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f78c8de1181a4659959fbf2deb1024b
https://doi.org/10.4049/jimmunol.133.4.2067
https://doi.org/10.4049/jimmunol.133.4.2067
Publikováno v:
Europe PubMed Central
KJ23a+ T cell clones, which bear the determinant encoded by the V beta 17a T cell receptor gene segment, frequently recognize IE molecules of various murine H-2 haplotypes. In the presence of IE molecules, thymic maturation of KJ23a+ clones is infreq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb7af648268a74ef3b583636c1340a29
https://doi.org/10.4049/jimmunol.141.6.1840
https://doi.org/10.4049/jimmunol.141.6.1840
Publikováno v:
Europe PubMed Central
Research on the specificities, functions, and maturation of T cells would be greatly aided by a collection of monoclonal antibodies which distinguishes different types of TCR. With this end in mind hamsters were immunized and tested for production of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35dd8d1f06ef69ec0a026175ebd8b1c7
https://doi.org/10.4049/jimmunol.142.8.2736
https://doi.org/10.4049/jimmunol.142.8.2736
Publikováno v:
Europe PubMed Central
The TCR alpha/beta variable element V beta 17a is expressed in all strains of mice carrying the V beta a complex in which about half of the V beta elements have been lost due to a large deletion. The mAb KJ23a detects V beta 17a containing alpha/beta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31f49bc9d4e84a826145c18da969ceeb
https://doi.org/10.4049/jimmunol.141.6.2165
https://doi.org/10.4049/jimmunol.141.6.2165
Publikováno v:
Europe PubMed Central
We determined if self-reactive T cells are able to escape thymic tolerance in autoimmune New Zealand mice. T cells utilizing V beta 17a and V beta 11 encoded receptors have been shown to be clonally eliminated in nonautoimmune mice expressing I-E bec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::da6b86462de0825276e22003b27b0ea7
https://pubmed.ncbi.nlm.nih.gov/2786535
https://pubmed.ncbi.nlm.nih.gov/2786535
Publikováno v:
Europe PubMed Central
Ligand binding to alpha beta TCR has different consequences in thymocytes at different developmental stages, causing alternatively positive selection, clonal deletion, or activation. These various functional consequences may be due to changes in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::633e8b9ca1a438a150292d107f302fba
https://pubmed.ncbi.nlm.nih.gov/2523422
https://pubmed.ncbi.nlm.nih.gov/2523422