Distribution of OX2 antigen and OX2 receptor within retina

Autor: Ad, Dick, Cathryn Broderick, Jv, Forrester, Gj, Wright

Publikováno v: Europe PubMed Central

OX2 is a member of the immunoglobulin superfamily expressed on a broad range of tissues including neurons of the central and peripheral nervous systems, thymocytes, and endothelium. The recently identified OX2 receptor (OX2R) is restricted to the sur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::306508ddffa07ffad778f11e5b48be70
http://europepmc.org/abstract/med/11133863

Ultrastructural pathology of S-antigen uveoretinitis

Autor: Jv, Forrester, Gm, Borthwick, Paul McMenamin

Publikováno v: Europe PubMed Central

The morphology of S-antigen-induced uveoretinitis in guinea pigs has been studied using transmission electron microscopy. Purified bovine retinal S-antigen was shown to produce a focal chorioretinitis, characterized by selective damage to the outer r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4fd4516f9379e60bee51977a97cb4c5b
http://europepmc.org/abstract/med/4030255

Ultrastructural pathology of experimental autoimmune uveitis. Quantitative evidence of activation and possible high endothelial venule-like changes in retinal vascular endothelium

Autor: Paul McMenamin, Jv, Forrester, Rj, Steptoe, Hs, Dua

Publikováno v: Europe PubMed Central

Experimental autoimmune uveitis (EAU) is a highly organ-specific autoimmune disease in which the target is the retinal photoreceptors. It is well recognized as a model of uveoretinitis in humans. The mechanisms that control the homing of sensitized l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e7e79ba66d95a32a00d6a98b8a9165ee
http://europepmc.org/abstract/med/1625447

Targeted delivery of autoantigen to dendritic cells prevents development of spontaneous uveitis.

Autor: Klaska IP; Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom., Yu T; Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.; Department of Ophthalmology, Beijing Hospital, National Center of Gerontology, Beijing, China., Fordyce R; Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom., Kamoi K; Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.; Department of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan., Cornall RJ; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Martin-Granados C; Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom., Kuffova L; Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.; Eye Clinic, Aberdeen Royal Infirmary, Aberdeen, United Kingdom., Forrester JV; Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 Sep 01; Vol. 14, pp. 1227633. Date of Electronic Publication: 2023 Sep 01 (Print Publication: 2023).

Colitis in a transgenic mouse model of autoimmune uveitis may be induced by neoantigen presentation in the bowel.

Autor: Mölzer C; Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK.; Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Vienna General Hospital, Währinger Gürtel 18-20, 1090, Vienna, Austria., Liu YH; Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK.; Flow Facility, University of Glasgow, Wolfson Wohl Cancer Research Centre, Switchback Road, Bearsden, G61 1BD, Glasgow, UK., Muckersie E; Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK., Klaska IP; Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK.; Centre for Gene Therapy and Regenerative Medicine, Guy's Hospital, Great Maze Pond, London, SE1 9RT, UK., Cornall R; Nuffield Department of Medicine, Henry Wellcome Building for Molecular Physiology, University of Oxford, Old Road Campus, Headington, Oxford, OX3 7BN, UK., Wilson HM; Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK., Kuffová L; Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK.; Eye Clinic, Aberdeen Royal Infirmary, NHS Grampian, Aberdeen, UK., Forrester JV; Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK. j.forrester@abdn.ac.uk.

Publikováno v: Scientific reports [Sci Rep] 2023 Jan 23; Vol. 13 (1), pp. 1256. Date of Electronic Publication: 2023 Jan 23.