Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Juyi Choi"'
Autor:
Bryan A. Kramer, Kevin Whelan, Yoshinori Sekiguchi, Shigeyuki Chaki, Pureza Vallar, Michael Morgan, Graeme Semple, Thuy-Anh Tran, William Thomsen, Dipanjan Sengupta, Juyi Choi, Debbie Hsu, Andrew J. Grottick, Kosuke Kanuma, Erin K. Hauser, Ning Zou, Martin Casper, Sangdon Han
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:6166-6171
A series of pyrimidine analogues derived from ATC0175 were potent antagonists of human MCH-R1 in vitro. Significantly improved receptor selectivity was achieved with several analogues from this series, but no improvement in brain partitioning was not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af68ef61e7341b4e649e225bb11aef8
https://doi.org/10.1016/j.bmcl.2009.09.003
https://doi.org/10.1016/j.bmcl.2009.09.003
Autor:
Young-Jun Shin, Hsin-Hui Shu, P. Douglas Boatman, Juyi Choi, Steve Chang, Michael Morgan, Graeme Semple, Peter Martens, John W. Adams, Ning Zou, David J. Unett, Yunqing Shi, Shiu-Feng Tung, Pureza Vallar, Bryan A. Kramer, Thuy-Anh Tran, Juan Ramirez
Publikováno v:
Bioorganicmedicinal chemistry letters. 25(5)
The design and synthesis of two closely related series of prostacyclin receptor agonist compounds that showed excellent human IP receptor potency and efficacy is described. Compounds from this series showed in vivo activity after SC dosing in the mon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f18b1b98bf673d82965b415adc56a6
https://pubmed.ncbi.nlm.nih.gov/25666818
https://pubmed.ncbi.nlm.nih.gov/25666818