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Assembly and Function of the Juxtaparanodal Kv1 Complex in Health and Disease

Autor: Delphine Pinatel, Catherine Faivre-Sarrailh

Publikováno v: Life, Vol 11, Iss 1, p 8 (2020)

The precise axonal distribution of specific potassium channels is known to secure the shape and frequency of action potentials in myelinated fibers. The low-threshold voltage-gated Kv1 channels located at the axon initial segment have a significant i

Externí odkaz: https://doaj.org/article/425fa9f6a57c4cc38a12ee02a762319f

Assembly and Function of the Juxtaparanodal Kv1 Complex in Health and Disease

Autor: Catherine Faivre-Sarrailh, Delphine Pinatel

Publikováno v: Life
Life, MDPI, 2021, 11 (1), pp.8. ⟨10.3390/life11010008⟩
Life, Vol 11, Iss 8, p 8 (2021)

International audience; The precise axonal distribution of specific potassium channels is known to secure the shape and frequency of action potentials in myelinated fibers. The low-threshold voltage-gated Kv1 channels located at the axon initial segm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbdd8dffc12498a70bb85ccfe92e3322
https://pubmed.ncbi.nlm.nih.gov/33374190

The Kv1-associated molecules TAG-1 and Caspr2 are selectively targeted to the axon initial segment in hippocampal neurons

Autor: Nelly Noraz, Maria Savvaki, Margaux Saint-Martin, Catherine Faivre-Sarrailh, Bruno Hivert, Delphine Pinatel, Domna Karagogeos

Publikováno v: Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2017, 130 (13), pp.2209-2220. ⟨10.1242/jcs.202267⟩
Journal of Cell Science, 2017, 130 (13), pp.2209-2220. ⟨10.1242/jcs.202267⟩

International audience; Caspr2 and TAG-1 (also known as CNTNAP2 and CNTN2, respectively) are cell adhesion molecules (CAMs) associated with the voltage-gated potassium channels Kv1.1 and Kv1.2 (also known as KCNA1 and KCNA2, respectively) at regions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::476c448d8743ae2886c9b64d555c36c8
https://hal.archives-ouvertes.fr/hal-02322304

Altered potassium channel distribution and composition in myelinated axons suppresses hyperexcitability following injury

Autor: Natalie Richards, David L.H. Bennett, Lan Zhu, Dinka Ivulic, Margarita Calvo, Annina B. Schmid, Ning Zhu, Felipe A. Court, Philipp Anwandter, Stephen B. McMahon, Manzoor A. Bhat, Alejandro Barroso

Publikováno v: eLife
Calvo, M, Richards, N, Schmid, A B, Barroso, A, Zhu, L, Ivulic, D, Zhu, N, Anwandter, P, Bhat, M A, Court, F A, McMahon, S B & Bennett, D L H 2016, ' Altered potassium channel distribution and composition in myelinated axons suppresses hyperexcitability following injury ', eLife, vol. 5, no. APRIL2016, e12661, pp. 1-26 . https://doi.org/10.7554/eLife.12661
eLife, Vol 5 (2016)
Artículos CONICYT
CONICYT Chile
instacron:CONICYT

Neuropathic pain following peripheral nerve injury is associated with hyperexcitability in damaged myelinated sensory axons, which begins to normalise over time. We investigated the composition and distribution of shaker-type-potassium channels (Kv1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a192f92c263551dbc96346715608202f
https://hdl.handle.net/10668/9965