Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Juxiang Chen"'
Publikováno v:
Journal of Rock Mechanics and Geotechnical Engineering, Vol 16, Iss 6, Pp 2033-2051 (2024)
Surrounding rocks of underground engineering are subjected to long-term seepage pressure, which can deteriorate the mechanical properties and cause serious disasters. In order to understand the impact of seepage pressure on the mechanical property of
Externí odkaz:
https://doaj.org/article/7c016542486d429caaa434ea60fca61b
Autor:
Zong Miao, Lei Xu, Wei Gu, Yimin Ren, Rong Li, Shuai Zhang, Chao Chen, Hongxiang Wang, Jing Ji, Juxiang Chen
Publikováno v:
Redox Biology, Vol 73, Iss , Pp 103220- (2024)
Temozolomide (TMZ) is a widely utilized chemotherapy treatment for patients with glioblastoma (GBM), although drug resistance constitutes a major therapeutic hurdle. Emerging evidence suggests that ferroptosis-mediated therapy could offer an appropri
Externí odkaz:
https://doaj.org/article/929b58daa077451dbffc8909fd5575f1
Autor:
Shuai Zhang, Lilin Cheng, Yandong Su, Zhongrun Qian, Zhen Wang, Chao Chen, Rong Li, Aikang Zhang, Jiawei He, Jiangxin Mao, Hongxiang Wang, Juxiang Chen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionGlioblastoma multiforme (GBM), the most common primary malignant brain tumor, is notorious for its aggressive growth and dismal prognosis. This study aimed to elucidate the molecular underpinnings of GBM, particularly focusing on the role
Externí odkaz:
https://doaj.org/article/9aed31809d4241fea68b53549cbe70ce
Autor:
Weiwei Dai, Ruotong Tian, Liubing Yu, Shasha Bian, Yuling Chen, Bowen Yin, Yuxuan Luan, Siqi Chen, Zhuoyang Fan, Rucheng Yan, Xin Pan, Yingyong Hou, Rong Li, Juxiang Chen, Minfeng Shu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Oncolytic virotherapy holds promise for cancer treatment, but the factors determining its oncolytic activity remain unclear. Neutrophil extracellular traps (NETs) are associated with cancer progression, yet their formation mechanism and role
Externí odkaz:
https://doaj.org/article/6b5e47a3450741aab2f364d93eacec2a
Autor:
Jinpiao Zhu, Chang Chen, Zhen Li, Xiaodong Liu, Jingang He, Ziyue Zhao, Mengying He, Binbin Nie, Zili Liu, Yingying Chen, Kuanpin Su, Xiang Li, Juxiang Chen, Hongbing Xiang, Fuqiang Xu, Kangguang Lin, Zongze Zhang, Jie Wang
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 11, Pp 2449-2458 (2023)
Sleep benefits the restoration of energy metabolism and thereby supports neuronal plasticity and cognitive behaviors. Sirt6 is a NAD+-dependent protein deacetylase that has been recognized as an essential regulator of energy metabolism because it mod
Externí odkaz:
https://doaj.org/article/1e8164e384d642af92ebab015d8ae8df
Publikováno v:
Water, Vol 16, Iss 4, p 532 (2024)
The degradation of sulfamethoxazole (SMX) via the Fe2+/Ultraviolet (UV)/sodium percarbonate (SPC) system was comprehensively investigated in this study, including the performance optimization, degradation mechanism, and predicting models. The degrada
Externí odkaz:
https://doaj.org/article/18ea79a2a977454883a49748da02ae13
Autor:
Yuanpei Li, Xiaoniu He, Xiao Lu, Zhicheng Gong, Qing Li, Lei Zhang, Ronghui Yang, Chengyi Wu, Jialiang Huang, Jiancheng Ding, Yaohui He, Wen Liu, Ceshi Chen, Bin Cao, Dawang Zhou, Yufeng Shi, Juxiang Chen, Chuangui Wang, Shengping Zhang, Jian Zhang, Jing Ye, Han You
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-23 (2022)
METTL3 catalyzes mRNA m6A deposition. The authors identify an acetylation-mediated regulation of METTL3 subcellular localization and compartment-specific functions, a process that is fine-tuned by anti-inflammatory and pro-inflammatory signals, which
Externí odkaz:
https://doaj.org/article/6d9c4809d19a4cadb353a7ca7474fad8
Autor:
Jinxiang Huang, Xinjie Hong, Zheng Cai, Qian Lv, Ying Jiang, Wei Dai, Guohan Hu, Yong Yan, Juxiang Chen, Xuehua Ding
Publikováno v:
Frontiers in Surgery, Vol 10 (2023)
ObjectiveTo investigate the learning curve under different surgical complexity in endoscopic transsphenoidal approach for pituitary adenoma.Methods273 patients undergoing endoscopic transsphenoidal surgery for pituitary adenoma were collected retrosp
Externí odkaz:
https://doaj.org/article/f12c8271a8e1463abd7d8c9962a42182
Publikováno v:
Water, Vol 15, Iss 17, p 3139 (2023)
Traditional 3D slope reliability analysis methods have high computational costs and are difficult to popularize in engineering practice. Under the framework of the limit equilibrium method with 3D slip surface normal stress correction, the critical h
Externí odkaz:
https://doaj.org/article/e2629a1279284ce2b815387fb473fedc
Autor:
Changqing Wu, Yu'e Liu, Wenju Liu, Tianhui Zou, Shaojuan Lu, Chengjie Zhu, Le He, Jie Chen, Lan Fang, Lin Zou, Ping Wang, Lihong Fan, Hongxiang Wang, Han You, Juxiang Chen, Jing‐Yuan Fang, Cizhong Jiang, Yufeng Shi
Publikováno v:
Advanced Science, Vol 10, Iss 1, Pp n/a-n/a (2023)
Abstract Lacking a clear understanding of the molecular mechanism determining cancer cell sensitivity to oxidative phosphorylation (OXPHOS) inhibition limits the development of OXPHOS‐targeting cancer treatment. Here, cancer cell lines sensitive or
Externí odkaz:
https://doaj.org/article/6f50b77a79ce457a8bac2916f5e2d073