Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Juxiang Cao"'
Autor:
John J. Skoko, Juxiang Cao, David Gaboriau, Myriam Attar, Alparslan Asan, Lisa Hong, Candice E. Paulsen, Hongqiang Ma, Yang Liu, Hanzhi Wu, Trey Harkness, Cristina M. Furdui, Yefim Manevich, Ciaran G. Morrison, Erika T. Brown, Daniel Normolle, Maria Spies, Michael Ashley Spies, Kate Carroll, Carola A. Neumann
Publikováno v:
Redox Biology, Vol 56, Iss , Pp 102443- (2022)
RAD51 is a critical recombinase that functions in concert with auxiliary mediator proteins to direct the homologous recombination (HR) DNA repair pathway. We show that Cys319 RAD51 possesses nucleophilic characteristics and is important for irradiati
Externí odkaz:
https://doaj.org/article/2fc66d80d6fa4b56ae9f41a240a26b8a
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167384 (2016)
Tuberous Sclerosis Complex (TSC) is an autosomal dominant tumor suppressor gene syndrome in which patients develop several types of tumors, including facial angiofibroma, subungual fibroma, Shagreen patch, angiomyolipomas, and lymphangioleiomyomatosi
Externí odkaz:
https://doaj.org/article/4cbc3f76f7684e43958b2df227b38f53
Autor:
Wenyi Wei, Pier Paolo Pandolfi, Rutao Cui, Marc W. Kirschner, Roderick T. Bronson, Lian Xue, Min Sup Song, Pengda Liu, Christopher Ng, Jacqueline Fung, Kelsey Berry, Jesse M. Katon, Hiroyuki Inuzuka, Jing Liu, Ying Lu, Su-Jung Song, Jinfang Zhang, Qing Yin, Xiangpeng Dai, Juxiang Cao, Ming Chen, Lixin Wan
Depletion of FZR1 leads to BRAF stabilization and subsequent ERK activation. Supplementary Figure S2. Depletion of FZR1 triggers the onset of premature senescence in primary melanocytes. Supplementary Figure S3. APCFZR1 promotes BRAF ubiquitination a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03cd0731522660e8f466b82fbc60bcf1
https://doi.org/10.1158/2159-8290.22531404.v1
https://doi.org/10.1158/2159-8290.22531404.v1
Autor:
David C. A. Gaboriau, Steven R. Woodcock, Carola A. Neumann, Erika T. Brown, Yefim Manevich, Ciaran G. Morrison, Yang Liu, Hongqiang Ma, Alparslan Asan, Bentley M. Wingert, Juxiang Cao, Kate S. Carroll, Myriam A. Attar, Carlos J. Camacho, John J. Skoko, Candice E. Paulsen, Chen Shan C. Woodcock, Bruce A. Freeman, Jennifer Schulte
Publikováno v:
SSRN Electronic Journal.
Peroxiredoxin 1 (PRDX1) senses and reduces peroxides and coordinates the signaling actions of its binding partners. We show that PRDX1 protects RAD51 from oxidation-induced repression of homologous recombination (HR) repair following ɣ-irradiation.
Autor:
David C. A. Gaboriau, Bentley M. Wingert, Ciaran G. Morrison, Hongqiang Ma, Steven R. Woodcock, Candice E. Paulsen, Juxiang Cao, Carola A. Neumann, Myriam A. Attar, Carlos J. Camacho, Alp Asan, Kate S. Carroll, John J. Skoko, Jennifer Schulte, Yang Liu, Bruce A. Freeman, Chen Shan C. Woodcock
Publikováno v:
Free Radical Biology and Medicine. 128:S73-S74
Peroxiredoxin 1 (PRDX1) is an oxidative stress protein sensor, which can coordinate cell signaling of its binding partners. Loss of Prdx1 function in mice has been shown to enhance susceptibility to various cancers, including breast cancer. Homologou
Autor:
Kelsey Berry, Jacqueline Fung, Wenyi Wei, C Ng, Pengda Liu, Ming Chen, Xiangpeng Dai, Pier Paolo Pandolfi, Min Sup Song, Jesse Katon, Marc W. Kirschner, Hiroyuki Inuzuka, Jing Liu, Lian Xue, Juxiang Cao, Rutao Cui, Roderick T. Bronson, Jinfang Zhang, Ying Lu, Lixin Wan, Su Jung Song, Qing Yin
BRAF drives tumorigenesis by coordinating the activation of the RAS/RAF/MEK/ERK oncogenic signaling cascade. However, upstream pathways governing BRAF kinase activity and protein stability remain undefined. Here, we report that in primary cells with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63070d0ad8fe5c03f8bc10bd24ebd79c
https://europepmc.org/articles/PMC5380472/
https://europepmc.org/articles/PMC5380472/
Publikováno v:
Yeast. 31:411-420
The yeast succinic semi-aldehyde dehydrogenase gene (SSADH; EC 1.2.1.16) was cloned and overexpressed in Escherichia coli. Based on SDS–PAGE, the molecular mass of the subunit was around 54 kDa, and the purified recombinant enzyme had a tetrameric
Autor:
Douglas V. Faller, Brandon J. English, Asami Takashima, Zhihong Chen, Rutao Cui, Juxiang Cao, Robert M. Williams
Publikováno v:
ACS Chemical Biology. 9:1003-1014
NRAS is the second most frequently mutated gene in melanoma. Previous reports have demonstrated the sensitivity of cancer cell lines carrying KRAS mutations to apoptosis initiated by inhibition of protein kinase C delta (PKCδ). Here, we report that
Autor:
Jennifer Schulte, Hongqiang Ma, Kate S. Carroll, Candice E. Paulsen, Chen-Shan Chen Woodcock, John J. Skoko, Bruce A. Freeman, Steven R. Woodcock, Bentley M. Wingert, David C. A. Gaboriau, Juxiang Cao, Myriam A. Attar, Carlos J. Camacho, Ciaran G. Morrison, Yang Liu, Carola A. Neumann, Alparslan Asan
Publikováno v:
Free Radical Biology and Medicine. 112:100-101
Peroxiredoxin 1 (PRDX1) senses and reduces peroxides and coordinates the signaling actions of its binding partners. Loss of Prdx1 function in mice has been shown to enhance susceptibility to various cancers, including breast cancer. Homologous recomb
Publikováno v:
Yeast. 30:279-289
GABA transaminase (GABA-T) catalyses the conversion of GABA to succinate semialdehyde (SSA) in the GABA shunt pathway. The GABA-T from Saccharomyces cerevisiae (ScGABA-TKG) is an α-ketoglutarate-dependent enzyme encoded by the UGA1 gene, while highe