Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Juwen C. DuBois"'
Autor:
Bridget Shafit-Zagardo, Simone Sidoli, James E. Goldman, Juwen C. DuBois, John R. Corboy, Stephen M. Strittmatter, Hillary Guzik, Ukuemi Edema, Anita G. Arackal, Yair M. Botbol, Emilio Merheb, Rashed M. Nagra, Sarah Graff
Publikováno v:
Cells, Vol 12, Iss 13, p 1734 (2023)
During inflammatory, demyelinating diseases such as multiple sclerosis (MS), inflammation and axonal damage are prevalent early in the course. Axonal damage includes swelling, defects in transport, and failure to clear damaged intracellular proteins,
Externí odkaz:
https://doaj.org/article/fd1f67f30de94928b8ba0eb64c0dde6f
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-14 (2020)
Abstract Background Multiple sclerosis is an immune-mediated disease of the central nervous system (CNS) characterized by inflammation, oligodendrocytes loss, demyelination, and damaged axons. Tyro3, Axl, and MerTK belong to a family of receptor tyro
Externí odkaz:
https://doaj.org/article/301f33a97b6a4cd184bc7d3e1e6903bf
Autor:
Juwen C. DuBois, Alex K. Ray, Ross C. Gruber, Yongwei Zhang, Ranee Aflakpui, Fernando Macian-Juan, Bridget Shafit-Zagardo
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Akt is a serine/threonine protein kinase that plays a major role in regulating multiple cellular processes. While the isoforms Akt1 and Akt2 are involved in apoptosis and insulin signaling, respectively, the role for Akt3 remains uncertain. Akt3 is p
Externí odkaz:
https://doaj.org/article/cd6ec02fc3794e0e92e4f11fad140795
Autor:
Graff, Bridget Shafit-Zagardo, Simone Sidoli, James E. Goldman, Juwen C. DuBois, John R. Corboy, Stephen M. Strittmatter, Hillary Guzik, Ukuemi Edema, Anita G. Arackal, Yair M. Botbol, Emilio Merheb, Rashed M. Nagra, Sarah
Publikováno v:
Cells; Volume 12; Issue 13; Pages: 1734
During inflammatory, demyelinating diseases such as multiple sclerosis (MS), inflammation and axonal damage are prevalent early in the course. Axonal damage includes swelling, defects in transport, and failure to clear damaged intracellular proteins,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::ec0427060b677c597080242dd445aa88
Autor:
Bridget Shafit-Zagardo, Simone Sidoli, James E. Goldman, Juwen C. DuBois, John R. Corboy, Stephen M. Strittmatter, Hillary Guzik, Sarah Graff, Rashed M. Nagra
During inflammatory, demyelinating diseases such as multiple sclerosis (MS) axonal damage is prevalent early in the disease course. Axonal damage includes swellings, defects in transport, and failure to clear damaged intracellular proteins, all of wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9957cca1e4ec047fa27baa138f27149
https://doi.org/10.1101/2022.05.05.490697
https://doi.org/10.1101/2022.05.05.490697
Autor:
Bridget Shafit-Zagardo, Min Hui Cui, Emilio Merheb, Robyn D. Moir, Maria Gulinello, Ian M. Willis, Juwen C. DuBois, Craig A. Branch
Publikováno v:
Proc Natl Acad Sci U S A
RNA polymerase (Pol) III synthesizes abundant short non-coding RNAs that have essential functions in protein synthesis, secretion and other processes. Despite the ubiquitous functions of these RNAs, mutations in Pol III subunits cause Pol III-related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e517ac91029ad804c2282c83957af67a
https://doi.org/10.1101/2020.12.09.418657
https://doi.org/10.1101/2020.12.09.418657
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-14 (2020)
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-14 (2020)
Background Multiple sclerosis is an immune-mediated disease of the central nervous system (CNS) characterized by inflammation, oligodendrocytes loss, demyelination, and damaged axons. Tyro3, Axl, and MerTK belong to a family of receptor tyrosine kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62e473e1d4162777a55b63bb3372f8a
https://pubmed.ncbi.nlm.nih.gov/33121494
https://pubmed.ncbi.nlm.nih.gov/33121494
Autor:
Geoffrey S. Perumal, Cedric S. Raine, Maria Gulinello, Lauren Kozakiewicz, Julie E. Williamson, Ross C. Gruber, Bridget Shafit-Zagardo, Hillary Guzik, Juwen C. DuBois, Alex K. Ray
Publikováno v:
Glia. 65:2051-2069
The TAM (Tyro3, Axl, and MerTK) family of receptor tyrosine kinases (RTKs) and their ligands, Gas6 and ProS1, are important for innate immune responses and central nervous system (CNS) homeostasis. While only Gas6 directly activates Axl, ProS1 activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7deda2ab74e91935ef0dd908891351
https://doi.org/10.1002/glia.23214
https://doi.org/10.1002/glia.23214
Autor:
Yongwei Zhang, Bridget Shafit-Zagardo, Fernando Macian-Juan, Juwen C. DuBois, Alex K. Ray, Ranee Aflakpui, Ross C. Gruber
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology
Frontiers in Immunology
Akt is a serine/threonine protein kinase that plays a major role in regulating multiple cellular processes. While the isoforms Akt1 and Akt2 are involved in apoptosis and insulin signaling, respectively, the role for Akt3 remains uncertain. Akt3 is p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3208d037c1d8bb5905266452cb9d24e
https://doi.org/10.3389/fimmu.2019.01738
https://doi.org/10.3389/fimmu.2019.01738
Autor:
Jessica E. Dade, Joseph A. Caruso, Rajamouli Pasula, A. George Smulian, Juwen C. DuBois, George S. Deepe, Anna M. Donnell
Publikováno v:
Medical Mycology. 54:865-875
Histoplasma capsulatum (Hc) exists in the soil and is capable of adapting to the shift in environment during infection to ensure survival. Yeast encounter a restrictive host environment low in nutrients such as zinc. In this study we functionally ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18cef63173c117c1bfd0afc88c256f45
https://doi.org/10.1093/mmy/myw045
https://doi.org/10.1093/mmy/myw045