Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Juw Won Park"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The high mutation rate of RNA viruses provides viral populations with the ability to adapt to new environments but also makes them vulnerable to extinction due to the deleterious effects of mutations, which is the conceptual basis for the an
Externí odkaz:
https://doaj.org/article/09f98a24a98d46e2a117fb007e194cf4
Tryptophan As a New Member of RNA‐Induced Silencing Complexes Prevents Colon Cancer Liver Metastasis
Autor:
Fangyi Xu, Yi Ren, Yun Teng, Jingyao Mu, Jie Tang, Kumaran Sundaram, Lifeng Zhang, Juw Won Park, Jae Yeon Hwang, Jun Yan, Gerald Dryden, Huang‐Ge Zhang
Publikováno v:
Advanced Science, Vol 11, Iss 31, Pp n/a-n/a (2024)
Abstract Essential amino acids (EAA) and microRNAs (miRs) control biological activity of a cell. Whether EAA regulates the activity of miR has never been demonstrated. Here, as proof‐of‐concept, a tryptophan (Trp, an EAA) complex containing Argon
Externí odkaz:
https://doaj.org/article/70b19b6668ac4a169c60d6e13864d25a
Autor:
Mukesh K. Sriwastva, Yun Teng, Jingyao Mu, Fangyi Xu, Anil Kumar, Kumaran Sundaram, Rajiv Kumar Malhotra, Qingbo Xu, Joshua L. Hood, Lifeng Zhang, Jun Yan, Michael L. Merchant, Juw Won Park, Gerald W. Dryden, Nejat K. Egilmez, Huang‐Ge Zhang
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 2, Pp n/a-n/a (2023)
Abstract Extracellular vesicles (EVs) contain more than 100 proteins. Whether there are EVs proteins that act as an ‘organiser’ of protein networks to generate a new or different biological effect from that identified in EV‐producing cells has
Externí odkaz:
https://doaj.org/article/33c5cd4cf6cb4bf493fc823ff60c3791
Autor:
Natoya J. Peart, Jae Yeon Hwang, Mathieu Quesnel-Vallières, Matthew J. Sears, Yuequin Yang, Peter Stoilov, Yoseph Barash, Juw Won Park, Kristen W. Lynch, Russ P. Carstens
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105205- (2022)
Summary: The epithelial splicing regulatory proteins, ESRP1 and ESRP2, are essential for mammalian development through the regulation of a global program of alternative splicing of genes involved in the maintenance of epithelial cell function. To fur
Externí odkaz:
https://doaj.org/article/c67b0c43228642c1bc61a396d81a760e
High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
Autor:
Anil Kumar, Kumaran Sundaram, Jingyao Mu, Gerald W. Dryden, Mukesh K. Sriwastva, Chao Lei, Lifeng Zhang, Xiaolan Qiu, Fangyi Xu, Jun Yan, Xiang Zhang, Juw Won Park, Michael L. Merchant, Henry C. L. Bohler, Baomei Wang, Shuangqin Zhang, Chao Qin, Ziying Xu, Xianlin Han, Craig J. McClain, Yun Teng, Huang-Ge Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
High-fat diet plays a role in development of insulin resistance. Here, the authors report a mechanism that underlies the development of diet induced insulin resistance through the activation of an aryl hydrocarbon receptor mediated signalling pathway
Externí odkaz:
https://doaj.org/article/197f808e92ba42869b26bfd32025af49
Autor:
Mohammed Sayed, Juw Won Park
Publikováno v:
Non-Coding RNA, Vol 9, Iss 1, p 11 (2023)
MicroRNAs (miRNAs) are small non-coding RNAs that are known for their role in the post-transcriptional regulation of target genes. Typically, their functions are predicted by first identifying their target genes and then finding biological processes
Externí odkaz:
https://doaj.org/article/b88d0aaa2e12428aa9719a5ee83d3af8
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Alternative splicing (AS) refers to the production of multiple mRNA isoforms from a single gene due to alternative selection of exons or splice sites during pre-mRNA splicing. It is a primary mechanism of gene regulation in higher eukaryotes and sign
Externí odkaz:
https://doaj.org/article/61e489948dd14fd4ac0d83494075c6ea
Autor:
Chao Lei, Yun Teng, Liqing He, Mohammed Sayed, Jingyao Mu, Fangyi Xu, Xiangcheng Zhang, Anil Kumar, Kumaran Sundaram, Mukesh K. Sriwastva, Lifeng Zhang, Shao-yu Chen, Wenke Feng, Shuangqin Zhang, Jun Yan, Juw Won Park, Michael L. Merchant, Xiang Zhang, Huang-Ge Zhang
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102511- (2021)
Summary: Diet and bile play critical roles in shaping gut microbiota, but the molecular mechanism underlying interplay with intestinal microbiota is unclear. Here, we showed that lemon-derived exosome-like nanoparticles (LELNs) enhance lactobacilli t
Externí odkaz:
https://doaj.org/article/b5e9d9b7a12441eda91e86920d613a65
Autor:
Mohamed Chaabane, Kalina Andreeva, Jae Yeon Hwang, Tae Lim Kook, Juw Won Park, Nigel G F Cooper
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 10, p e1008338 (2020)
Over the past two decades, researchers have discovered a special form of alternative splicing that produces a circular form of RNA. Although these circular RNAs (circRNAs) have garnered considerable attention in the scientific community for their bio
Externí odkaz:
https://doaj.org/article/9891f01e45f1491d8bbe8f503d5afcdd
Autor:
Navatha Alugubelly, Afzaal N. Mohammed, Mariola J. Edelmann, Bindu Nanduri, Mohammed Sayed, Juw Won Park, Russell L. Carr
Publikováno v:
Data in Brief, Vol 27, Iss , Pp - (2019)
This data article contains the proteomic and transcriptomic data of the amygdala of adolescent rats involved in social play compared to non-behavioural animals. Social play was performed on male Sprague Dawley rats on postnatal day 38 and protein and
Externí odkaz:
https://doaj.org/article/e2240098ed3f44e3acc3a52600b197e5