Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Juuli Raivola"'
Autor:
Emilia Piki, Alice Dini, Juuli Raivola, Kari Salokas, Kaiyang Zhang, Markku Varjosalo, Teijo Pellinen, Katja Välimäki, Kristina Tabor Veskimäe, Synnöve Staff, Sampsa Hautaniemi, Astrid Murumägi, Daniela Ungureanu
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Wnt pathway dysregulation through genetic and non-genetic alterations occurs in multiple cancers, including ovarian cancer (OC). The aberrant expression of the non-canonical Wnt signaling receptor ROR1 is thought to contribute to OC progress
Externí odkaz:
https://doaj.org/article/a88f0a5d9ef74d3ba66b390c6a8db639
Autor:
Juuli Raivola, Alice Dini, Hanna Karvonen, Emilia Piki, Kari Salokas, Wilhelmiina Niininen, Laura Kaleva, Kaiyang Zhang, Mariliina Arjama, Greta Gudoityte, Brinton Seashore-Ludlow, Markku Varjosalo, Olli Kallioniemi, Sampsa Hautaniemi, Astrid Murumägi, Daniela Ungureanu
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-12 (2022)
Abstract Most patients with ovarian cancer (OC) are diagnosed at a late stage when there are very few therapeutic options and a poor prognosis. This is due to the lack of clearly defined underlying mechanisms or an oncogenic addiction that can be tar
Externí odkaz:
https://doaj.org/article/47baa86ead214039b8cd980a88935c5f
Autor:
Juuli Raivola, Henrik M. Hammarén, Anniina T. Virtanen, Vilasha Bulleeraz, Alister C. Ward, Olli Silvennoinen
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Janus kinase 3 (JAK3) tyrosine kinase has a central role in the control of lymphopoiesis, and mutations in JAK3 can lead to either severe combined immunodeficiency or leukemia and lymphomas. JAK3 associates with the common gamma chain (γc) receptor
Externí odkaz:
https://doaj.org/article/821fa515d8e54472ab3910b94443ecca
Publikováno v:
Methods in enzymology. 667
The majority of drug screening approaches are performed using recombinant proteins, however, drug binding to its target(s) in cells should be also assessed, especially for drugs aimed at modulating intracellular signaling pathways. As a result, the d
Autor:
Juuli Raivola, Alice Dini, Kari Salokas, Hanna Karvonen, Wilhelmiina Niininen, Emilia Piki, Markku Varjosalo, Daniela Ungureanu
ROR1, ROR2, and PTK7 are Wnt ligand-binding members of the receptor tyrosine kinase family. Despite their lack of catalytic activity, these receptors regulate skeletal, cardiorespiratory, and neurological development during embryonic and fetal stages
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22dd1d985a5fb13438693e4978bc089b
https://trepo.tuni.fi/handle/10024/141254
https://trepo.tuni.fi/handle/10024/141254
Publikováno v:
Methods in Enzymology ISBN: 9780323915410
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f29d2023064b3e9c8bd241caeabe4207
https://doi.org/10.1016/bs.mie.2022.03.038
https://doi.org/10.1016/bs.mie.2022.03.038
Publikováno v:
Cytokine. 118:48-63
The JAK-STAT signal transduction pathway is responsible for mediating signals of over fifty cytokines, growth factors and hormones. Signaling through the JAK-STAT pathway is regulated on multiple levels, including intramolecular regulation by the JAK
Publikováno v:
Cancers
Cancers, Vol 13, Iss 800, p 800 (2021)
Cancers, Vol 13, Iss 800, p 800 (2021)
Simple Summary Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is a crucial cell signaling pathway that drives the development, differentiation, and function of immune cells and has an important role in blood cell f
Publikováno v:
Encyclopedia of Molecular Pharmacology ISBN: 9783030215736
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6265f089e88f85b7de212f8b14fcd383
https://doi.org/10.1007/978-3-030-21573-6_10072-1
https://doi.org/10.1007/978-3-030-21573-6_10072-1
Publikováno v:
Cancers
Volume 12
Issue 1
Cancers, Vol 12, Iss 1, p 78 (2019)
Volume 12
Issue 1
Cancers, Vol 12, Iss 1, p 78 (2019)
The Janus kinase-signal transducer and activator of transcription protein (JAK-STAT) pathway mediates essential biological functions from immune responses to haematopoiesis. Deregulated JAK-STAT signaling causes myeloproliferative neoplasms, leukaemi