Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jutta Steinberger"'
Autor:
Xianbing Zhu, Zheng Fu, Shary Y. Chen, Dionzie Ong, Giulio Aceto, Rebecca Ho, Jutta Steinberger, Anie Monast, Virginie Pilon, Eunice Li, Monica Ta, Kyle Ching, Bianca N. Adams, Gian L. Negri, Luc Choiniere, Lili Fu, Kitty Pavlakis, Patrick Pirrotte, Daina Z. Avizonis, Jeffrey Trent, Bernard E. Weissman, Ramon I. Klein Geltink, Gregg B. Morin, Morag Park, David G. Huntsman, William D. Foulkes, Yemin Wang, Sidong Huang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract SMARCA4 (BRG1) and SMARCA2 (BRM) are the two paralogous ATPases of the SWI/SNF chromatin remodeling complexes frequently inactivated in cancers. Cells deficient in either ATPase have been shown to depend on the remaining counterpart for surv
Externí odkaz:
https://doaj.org/article/9b0a23025ed145939844545536f59b3f
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52065 (2012)
Translation directed by several picornavirus IRES elements can usually take place after cleavage of eIF4G by picornavirus proteases 2A(pro) or L(pro). The hepatitis A virus (HAV) IRES is thought to be an exception to this rule because it requires int
Externí odkaz:
https://doaj.org/article/d5b537f6e53d483185f626e12eefadda
Autor:
Xianbing Zhu, Zheng Fu, Shary Chen, Dionzie Ong, Giulio Aceto, Rebecca Ho, Jutta Steinberger, Eunice Li, David Huntsman, William Foulkes, Sidong Huang, Yemin Wang
Publikováno v:
Cancer Research. 83:3671-3671
SMARCA4 (BRG1) and SMARCA2 (BRM) are the two paralogous ATPases of the SWI/SNF chromatin remodelling complexes. These two ATPases are frequently inactivated in cancers and cancer cells deficient in either of them have been shown to depend on the rema
Autor:
Brahm J. Yachnin, Sai Kiran Naineni, Mehdi Amiri, Jutta Steinberger, Jerry Pelletier, Sarah A.E. Aboushawareb, Stephen J Kiniry, Francis Robert, Regina Cencic, Pavel V. Baranov, Nahum Sonenberg, Jennifer Chu, Leo Shen, Rayelle Itoua Maïga
Publikováno v:
Nucleic Acids Research
Hippuristanol (Hipp) is a natural product that selectively inhibits protein synthesis by targeting eukaryotic initiation factor (eIF) 4A, a DEAD-box RNA helicase required for ribosome recruitment to mRNA templates. Hipp binds to the carboxyl-terminal
Autor:
Caitlynn N. Mirabelli, Rachel La Selva, John Heath, Steven Hébert, Jutta Steinberger, Jialin Jiang, Claudia Kleinman, Sidong Huang, Josie Ursini-Siegel
Publikováno v:
Cancer Research. 82:126-126
Breast cancer is the most commonly diagnosed malignancy in women worldwide. It is a molecularly heterogeneous disease, which poses difficulties in the treatment of more advanced cancers. Despite this fact, the mechanisms contributing to the emergence
Publikováno v:
Cellular and molecular life sciences : CMLS. 74(9)
Biotherapeutics have revolutionized modern medicine by providing medicines that would not have been possible with small molecules. With respect to cancer therapies, this represents the current sector of the pharmaceutical industry having the largest
Autor:
Jerry Pelletier, Philip G. Williams, Yasuhiro Igarashi, John A. Porco, Maxime Hallé, Dylan Pelletier, Brian O. Bachmann, David E. Williams, Abimael D. Rodríguez, Francis Robert, Neha Sawhney, Regina Cencic, Raymond J. Andersen, Jutta Steinberger, Brigitte Kopp
Publikováno v:
Cell Chem Biol
Our inability to effectively “drug” targets such as MYC for therapeutic purposes requires the development of new approaches. We report on the implementation of a phenotype-based assay for monitoring MYC expression in multiple myeloma cells. The o
Autor:
Jutta, Steinberger, Irina, Grishkovskaya, Regina, Cencic, Luiz, Juliano, Maria A, Juliano, Tim, Skern
Publikováno v:
Virology
Translation of foot-and-mouth disease virus RNA initiates at one of two start codons leading to the synthesis of two forms of leader proteinase Lpro (Labpro and Lbpro). These forms free themselves from the viral polyprotein by intra- and intermolecul
Autor:
Tim Skern, Jutta Steinberger
Publikováno v:
Biological Chemistry
The leader proteinase (Lpro) of the foot-and-mouth disease virus inhibits the host innate immune response by at least three different mechanisms. The most well-characterised of these is the prevention of the synthesis of cytokines such as interferons
Publikováno v:
Viral Proteases and Antiviral Protease Inhibitor Therapy ISBN: 9789048123476
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c36e4351a63999b9064ba2015a502bff
https://doi.org/10.1007/978-90-481-2348-3_6
https://doi.org/10.1007/978-90-481-2348-3_6