Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Jutong Si"'
Autor:
Steven J. Collins, Jutong Si
Ca2+ signaling is an important component of signal transduction pathways regulating B and T lymphocyte proliferation, but the functional role of Ca2+ signaling in regulating myeloid leukemia cell proliferation has been largely unexplored. We observe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120a21c71b80e1cee4ab6ed675c35241
https://doi.org/10.1158/0008-5472.c.6497205.v1
https://doi.org/10.1158/0008-5472.c.6497205.v1
Autor:
Steven J. Collins, Jutong Si
Supplementary Figure 1 from Activated Ca2+/Calmodulin-Dependent Protein Kinase IIγ Is a Critical Regulator of Myeloid Leukemia Cell Proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a3370af3e4b65c65c6c3336c8577fb
https://doi.org/10.1158/0008-5472.22373778
https://doi.org/10.1158/0008-5472.22373778
Publikováno v:
Cancer Letters. 299:45-53
The NF-κB is best known for its role in inflammation. Here we show that constitutive NF-κB activity in cancer cells promotes the biosynthesis of redox scavenger glutathione (GSH), which in turn confers resistance to oxidative stress. Inhibition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e976fed7ab19ea3474ff8ee5c911f0
https://doi.org/10.1016/j.canlet.2010.08.002
https://doi.org/10.1016/j.canlet.2010.08.002
Autor:
Markku Tammi, Jutong Si, Kirsi Rilla, Elina Koli, Pertti Nurminen, Raija Tammi, Anne Kultti, Katri M. Makkonen, Riikka Kärnä
Publikováno v:
Journal of Biological Chemistry. 285:22901-22910
Hyaluronan synthases (HAS1-3) are integral plasma membrane proteins that synthesize hyaluronan, a cell surface and extracellular matrix polysaccharide necessary for many biological processes. It has been shown that HAS is partly localized in choleste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dcf1305060f28a053ec324b6bc9046f
https://doi.org/10.1074/jbc.m109.088435
https://doi.org/10.1074/jbc.m109.088435
Autor:
Jutong Si, Steven J. Collins
Publikováno v:
Cancer Research. 68:3733-3742
Ca2+ signaling is an important component of signal transduction pathways regulating B and T lymphocyte proliferation, but the functional role of Ca2+ signaling in regulating myeloid leukemia cell proliferation has been largely unexplored. We observe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e603706b6c12ec3e534e6e1a08b33e3
https://doi.org/10.1158/0008-5472.can-07-2509
https://doi.org/10.1158/0008-5472.can-07-2509
Publikováno v:
Blood Cells, Molecules, and Diseases. 39:307-315
Certain myeloid leukemia cells, particularly the acute promyelocytic leukemia (APL) subset, undergo terminal granulocytic differentiation in response to retinoic acid (RA). RA mediates its biologic effects through specific retinoic acid receptors (RA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce683e10fadf5b078045bb5ae926b09f
https://doi.org/10.1016/j.bcmd.2007.05.009
https://doi.org/10.1016/j.bcmd.2007.05.009
Publikováno v:
Journal of Clinical Investigation. 117:1412-1421
Retinoic acid receptors (RARs) are members of the nuclear hormone receptor family and regulate the proliferation and differentiation of multiple different cell types, including promyelocytic leukemia cells. Here we describe a biochemical/functional i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8033c81dab66b2319d9f4ec856b5113c
https://doi.org/10.1172/jci30779
https://doi.org/10.1172/jci30779
Publikováno v:
Blood. 99:746-753
The disruption of retinoic acid receptor (RAR) activity that characterizes human acute promyelocytic leukemia (APL) is associated with a block to granulocytic differentiation indicating that RARs are critical regulators of normal myeloid differentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef948c5442be1117e93bfdacd8167049
https://doi.org/10.1182/blood.v99.3.746
https://doi.org/10.1182/blood.v99.3.746
Publikováno v:
Journal of Biological Chemistry. 271:19752-19759
Transcription of genes encoding nicotinic acetylcholine receptor (AChR) subunits (alpha, beta, gamma or epsilon, and delta) is highest in nuclei localized to the synaptic region of the muscle, which contributes to maintain a high density of AChRs at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff414029b008063ec735ae1bc8430fd
https://doi.org/10.1074/jbc.271.33.19752
https://doi.org/10.1074/jbc.271.33.19752
Publikováno v:
Life Sciences. 57:1459-1466
Protein tyrosine phosphorylation is prevalent throughout the nervous system. It has been implicated to play an important role in the development and maintenance of neuronal functions. In the past few years significant advances have been made in our u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3aca26722579912a7d2469e8d355dd
https://doi.org/10.1016/0024-3205(95)02118-3
https://doi.org/10.1016/0024-3205(95)02118-3