Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jutaro Shudo"'
Autor:
Richard D. Hamlin, Betsy Huang, Jutaro Shudo, Fatima M. Arjmand, Kevin Dines, Susan R. Meier-Davis, Chad Christianson, Tetsuto Nagata, Jainye Wen
Publikováno v:
Cutaneous and Ocular Toxicology. 31:312-317
Transdermal patch administration results in a locally high concentration of drug that induce local toxicity, including tumorogenicity. As a worst-case scenario for consequences of repeated application on neoplastic growth, the melanin-binding drug, r
Publikováno v:
Cutaneous and Ocular Toxicology. 31:20-25
The relationship between allergic contact dermatitis (ACD) and age has not been well documented. We searched for articles and textbooks based on age-ACD relationship and evaluated relevant data. The frequency of skin reactions to allergens increased
Autor:
Masahiro Yamaji, Jutaro Shudo
Publikováno v:
International Immunopharmacology. 9:984-989
Epicutaneous application of a contact sensitizer 2, 4-dinitro-1-chlorobenzene (DNCB) is known to cause an inflammatory response and a hapten-specific T cell activation. We developed a highly stable gel formulation for DNCB which is easy to apply to t
Autor:
Lisa M. Diehl, Min Meng, Jutaro Shudo, Susan R. Meier-Davis, Fatima M. Arjmand, Betsy Huang, Rebecca M. Lucke, Tetsuto Nagata, Weiwei Yuan, Jianye Wen
Publikováno v:
International journal of toxicology. 31(4)
Donepezil hydrochloride is a reversible acetyl cholinesterase inhibitor approved for Alzheimer disease treatment. As an alternate therapy, a donepezil hydrochloride transdermal patch is in development. Recommended nonclinical safety studies include a
Autor:
C. Toole, Jianye Wen, B. Cayme, Tetsuto Nagata, Susan R. Meier-Davis, L. Dieh, Jutaro Shudo, R. Murgasova, F. M. Arjm
Publikováno v:
Journal of Drug Metabolism & Toxicology. 3
Donepezil hydrochloride is a centrally acting, reversible acetyl cholinesterase inhibitor approved for Alzheimer’s disease therapy. Donepezil is marketed as an oral tablet but a transdermal patch may have advantages as an alternate therapy. To dete
Autor:
Masahiro Yamaji, Fatima M. Arjm, Susan R. Meier-Davis, Yoshiko Katori-Stowell, Tetsuto Nagata, Jianye Wen, Jutaro Shudo, Marie-Eve Rodrigue
Publikováno v:
Journal of Drug Metabolism & Toxicology. 3
Donepezil hydrochloride formulated in a transdermal patch for weekly administration is an alternative to the approved daily oral tablet. Transdermal delivery has a locally high concentration at the application site causing potential safety issues. To
Publikováno v:
Cutaneous and ocular toxicology. 31(2)
Knowledge on age-relationship to irritant contact dermatitis (ICD) remains of interest. We searched for articles and textbooks on age-relationship to ICD and evaluated relevant data. Irritant response may be enhanced in children and decline with incr