Contributors

Autor: Maha R.A. Abdollah, Mir Hilal Ahmad, Berta Alcover-Sanchez, Alfonso Alfaro Rodríguez, Marwa A. Ali, Karim A. Alkadhi, Georg Auburger, Meheli Banerjee, Christoph G. Baums, Daria V. Belan, Tom Bleeser, Larisa Bobrovskaya, Hayrunnisa Bolay, Joline E. Brandenburg, Josiane Budni, Jennifer Burnsed, Antonio Cadiz, Katherine Carlin, Raul Chavez-Valdez, Win Ning Chen, Jacques-Olivier Coq, Stephen J. Crocker, Beatriz Cubelos, I.S. Darshini, Nicole de Buhr, Justine Debatisse, Isaac Deng, Jan Deprest, Sarah Devroe, Maria Laura Cecconi dos Santos, Olga Doszyn, Tomasz Dulski, Omer Faruk Eker, Irina V. Ekimova, Barbara Falquetto, Ana Fernández, Matthew J. Fogarty, Abdelrahman Y. Fouda, Luis Gandía, Antonio G. García, Angélica González Maciel, Denis Grandgirard, Bernadette E. Grayson, David A. Greenberg, Natalia Gulyaeva, Sangeetha Gupta, Bora Gürer, Omar Guzmán-Quevedo, Daniel Gyamfi, Sarah Hamimi, Junqiu He, Sung-Ha Hong, Hiroyuki Ida, Salinee Jantrapirom, Lauren L. Jantzie, Mykola Kadzhaya, Jyotshna Kanungo, Ginpreet Kaur, Gabriela Serafim Keller, Sally Kelliny, Olga N. Kokiko-Cochran, Ilia Komoltsev, P. Pramod Kumar, Diego Cabral Lacerda, Geoffrey A. Lambert, Ksenia V. Lapshina, Tally M. Largent-Milnes, Ngoc Dung Le, Stephen L. Leib, Aidan A. Levine, Lulin Li, Erika Liktor-Busa, Fang Liu, Sufang Liu, Jian Luo, Raul Manhães-de-Castro, Devin W. McBride, Eduarda Behenck Medeiros, Marita Meurer, Brandon A. Miller, Amal Chandra Mondal, Thiago S. Moreira, S. Priya Narayanan, Andy Nguyen, Andrii Panteleichuk, Nuria Paricio, Yuri F. Pastukhov, Vinood B. Patel, Eugene Pedachenko, Misha Perouansky, Taras Petriv, Luca Lo Piccolo, K.V. Harish Prashanth, Victor R. Preedy, Cristina Puig, Rajkumar Rajendram, Ramalakshmi Ramasamy, Santhamani Ramasamy, Manuel Alejandro Ramirez-Lee, Trenton J. Ray, Lisienny Campoli Tono Rempel, Miriam Renz, Steffen Rex, Rafael Reynoso Robles, Susanna Ricci, Sandra Rieger, Shenandoah Robinson, Rosa María Romero Velázquez, Robert Rümmler, Francisco José Sanz, Serhii Savosko, Nada K. Sedky, Nesli-Ece Sen, Mohd. Farooq Shaikh, Shengshuai Shan, Uma Sharma, Anna Shmeleva, Gary C. Sieck, Pascal Siegert, Allie M. Smith, Phillip P. Smith, Cristina Solana-Manrique, Emmanuelle Canet Soulas, Rhea Subba, Selvakumar Subbian, Ana C. Takakura, John C. Talpos, Kin Yip Tam, Feng Tao, Zoe Tapp, Baban S Thawkar, Mai F. Tolba, Ana Elisa Toscano, Masahiro Tsuji, Ignacio Valenzuela, Marc Van de Velde, Lennart Van der Veeken, Libor Velíšek, Jana Velíšková, Diego Bulcão Visco, Sydney M. Vita, Maren von Köckritz-Blickwede, Doga Vuralli, Jennifer L. Walters, David A. Wassarman, Océane Wateau, Masamitsu Yamaguchi, Hideki Yoshida, Xin-Fu Zhou, Justyna Zmorzynska

Publikováno v: Handbook of Animal Models in Neurological Disorders ISBN: 9780323898331

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6229622e8dddc128548ffb0f2a9f3ec5
https://doi.org/10.1016/b978-0-323-89833-1.09993-6

mTORC1 hyperactivation causes sensory integration deficits due to habenula impairment

Autor: Olga Doszyn, Magdalena Kedra, Justyna Zmorzynska

Mechanistic target of rapamycin complex 1 (mTORC1) is an integration hub for extracellular and intracellular signals necessary for proper brain development. Hyperactivation of mTORC1 is found in many developmental diseases, including autism spectrum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f5e48fbba739c35e7fe05d2b3103fd21
https://doi.org/10.1101/2022.07.20.500762

G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling

Autor: Christiane A. Opitz, Ulrike Rehbein, Laura Brohée, Aurelio A. Teleman, Alexander Martin Heberle, Constantinos Demetriades, Marti Cadena Sandoval, Wilhelm Palm, Jose Miguel Ramos Pittol, Matylda Macias, Saskia Trump, Katharina Kern, Bianca Berdel, Andreas von Deimling, Birgit Holzwarth, Bernadette Carroll, Ines Heiland, Ann-Sofie De Meulemeester, Mirja Tamara Prentzell, Aleksandra Siekierska, Kathrin Thedieck, Jacek Jaworski, Mark Nellist, Hannah West, Mariana E. G. de Araujo, Mathias Bockwoldt, Eduard Stefan, Friederike Reuter, Michèle Reil, Andrii Kopach, Sandra Woltering, Suvagata Roy Chowdhury, Stefan Pusch, Viktor I. Korolchuk, Ralf Baumeister, Magdalena Kedra, Justyna Zmorzynska, Julian R. Sampson, Teodor E. Yordanov, Ineke van 't Land-Kuper, Chloë Scheldeman, Omar Torres-Quesada, Anja Reintjes, Lukas A. Huber, Gianluca Figlia, Peter de Witte, Laura E. Thomas

Publikováno v: Cell
2021, ' G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling ', Cell, vol. 184, no. 3, pp. 655-674.e27 . https://doi.org/10.1016/j.cell.2020.12.024
Cell, 184(3), 655-674.e27. Cell Press
Cell, 184(3), 655-674.e27. CELL PRESS

Summary Ras GTPase-activating protein-binding proteins 1 and 2 (G3BP1 and G3BP2, respectively) are widely recognized as core components of stress granules (SGs). We report that G3BPs reside at the cytoplasmic surface of lysosomes. They act in a non-r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1988cff1d6a25e654c51d5e842f355
https://hdl.handle.net/10037/21857

Tuberous sclerosis complex: From molecular biology to novel therapeutic approaches

Autor: Jacek Jaworski, Aleksandra Janusz-Kaminska, Katarzyna Kotulska, Justyna Zmorzynska, Katarzyna Switon

Publikováno v: IUBMB Life. 68:955-962

Tuberous sclerosis complex (TSC) is a rare multi-system disorder, primary manifestations of which are benign tumors and lesions in various organs of the body, including the brain. TSC patients often suffer from epilepsy, mental retardation, and autis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b4302dfe036e91619783cd3d21f562a
https://doi.org/10.1002/iub.1579