Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Justyna Zdrojewska"'
Autor:
Niina M. Santio, Veera Vainio, Tuuli Hoikkala, Kwan Long Mung, Mirka Lång, Riitta Vahakoski, Justyna Zdrojewska, Eleanor T. Coffey, Elena Kremneva, Eeva-Marja Rainio, Päivi J. Koskinen
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-18 (2020)
Abstract Background The PIM family kinases promote cancer cell survival and motility as well as metastatic growth in various types of cancer. We have previously identified several PIM substrates, which support cancer cell migration and invasiveness.
Externí odkaz:
https://doaj.org/article/c6113ca78a2d4e5a904995714f15db27
Autor:
Suominen Suominen, Justyna Zdrojewska, Jenni Mäki-Jouppila, Philip Dube, Ivan Gladwyn-Ng, Paul Volden, Jukka Rissanen, Mari Suominen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/9463b91a07d64499938ca92f18e52ed3
Autor:
Arne Scholz, Matias Knuuttila, Justyna Zdrojewska, Mari I. Suominen, Esa Alhoniemi, Christoph A. Schatz, Sabine Zitzmann-Kolbe, Sanna-Maria Käkönen, Urs B. Hagemann
Publikováno v:
Cancer Research. 83:5043-5043
Radium-223, a bone-specific alpha particle therapy, increased survival of patients with metastatic castration-resistant prostate cancer (mCRPC) and bone metastases (Parker et al., NEJM 2013) 177Lu-PSMA-617 is a small molecule radioligand that deliver
Autor:
Mari I. Suominen, Justyna Zdrojewska, Yvonne Konkol, Katja M. Fagerlund, Mervi Ristola, Jukka P. Rissanen
Publikováno v:
Cancer Research. 83:49-49
Oncology drug development has markedly lower success rate (3.4%) than other indications (20.9%) as reported by Wong, Siah and Lo in 2019. Animal models are often pointed at as the culprits for failure in clinical trials. While better animal models fo
Autor:
Eleanor T. Coffey, Niina M. Santio, Mirka Lång, Päivi J. Koskinen, Riitta L. Vahakoski, Eeva-Marja Rainio, Veera Vainio, Tuuli Hoikkala, Justyna Zdrojewska, Elena Kremneva, Kwan Long Mung
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-18 (2020)
Cell Communication and Signaling : CCS
Cell Communication and Signaling : CCS
Background The PIM family kinases promote cancer cell survival and motility as well as metastatic growth in various types of cancer. We have previously identified several PIM substrates, which support cancer cell migration and invasiveness. However,
Autor:
Justyna Zdrojewska, Mari Suominen, Shirin Katoozi, Katja Fagerlund, Jukka Rissanen, Roger Malerbakken-Bjerke, Jenny Karlsson
Publikováno v:
Cancer Research. 82:1662-1662
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and was listed as the third cause of death by cancer in 2020 (WHO). Hepatocarcinogenesis is a multistep process and to date it is still poorly understood. HCC occurs almos
Autor:
Paul Volden, Suominen Suominen, Jenni H. Mäki-Jouppila, Mari I. Suominen, Justyna Zdrojewska, Philip E. Dubé, Jukka P. Rissanen, Ivan Gladwyn-Ng
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background The recent KEYNOTE-199 trial raises hope for new treatment options for prostate cancer patients with the encouraging results of checkpoint inhibitor activity in a subset of prostate cancer patients, also including patients with bone-predom
Autor:
Katja M. Fagerlund, Ivan Gladwyn-Ng, Justyna Zdrojewska, Jenni H. Mäki-Jouppila, Jukka P. Rissanen, Ross Horn, Mari I. Suominen
Publikováno v:
Cancer Research. 81:1806-1806
Triple-negative breast cancer (TNBC) is one of the most complicated types of breast cancer to treat. However, clinical trials continue to demonstrate that combining immunotherapy with chemotherapy can improve survival in patients with metastatic TNBC
Autor:
Justyna Zdrojewska, Jenni H. Mäki-Jouppila, Masi Valkonen, Pekka Ruusuvuori, Tiina E. Kähkönen, Jenni Bernoulli, Jussi M. Halleen
Publikováno v:
Cancer Research. 80:1634-1634
Prostate cancer is the most common cancer in men. Upon diagnosed malignancy the growth of the tumors is androgen driven in a majority of the cases. For that reason, the tumors are treated with androgen deprivation therapy (ADT) to stop or reduce tumo
Autor:
Justyna Zdrojewska, Mari I. Suominen, Katja M. Fagerlund, Jussi M. Halleen, Jenni Bernoulli, Johann Zimmermann
Publikováno v:
Cancer Research. 79:2007-2007
Metastatic breast cancer (MBC) is the most advanced stage of breast cancer, diagnosed as stage IV. Typically, MBC metastases occur in the bones, liver, brain, and lungs. Bone metastases cause significant morbidity and mortality in late-stage breast c