Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Justyna Wojno"'
Autor:
Trusha Nana, Chanelle Moore, Tom Boyles, Adrian J. Brink, Joy Cleghorn, Lesley M. Devenish, Briette du Toit, Ernst S. Fredericks, Molebogeng R. Lekalakala-Mokaba, Caroline Maluleka, Muhammad N. Rajabally, Gary Reubenson, Liliwe Shuping, Karin Swart, Khine Swe Swe Han, Jeannette Wadula, Justyna Wojno, Warren Lowman
Publikováno v:
Southern African Journal of Infectious Diseases, Vol 35, Iss 1, Pp e1-e26 (2020)
Clostridioides difficile infection (CDI) is a problem in both developed and developing countries and is a common hospital-acquired infection. This guideline provides evidence-based practical recommendations for South Africa and other developing count
Externí odkaz:
https://doaj.org/article/78b280f466ab44aea75ed96165af7302
Autor:
Christopher R. Wellaway, Ian R. Baldwin, Paul Bamborough, Daniel Barker, Michelle A. Bartholomew, Chun-wa Chung, Birgit Dümpelfeld, John P. Evans, Neal J. Fazakerley, Paul Homes, Steven P. Keeling, Xiao Q. Lewell, Finlay W. McNab, Joanne Morley, Deborah Needham, Margarete Neu, Antoon J. M. van Oosterhout, Anshu Pal, Friedrich B. M. Reinhard, Francesco Rianjongdee, Craig M. Robertson, Paul Rowland, Rishi R. Shah, Emma B. Sherriff, Lisa A. Sloan, Simon Teague, Daniel A. Thomas, Natalie Wellaway, Justyna Wojno-Picon, James M. Woolven, Diane M. Coe
Publikováno v:
Journal of Medicinal Chemistry. 65:633-664
The Janus family of tyrosine kinases (JAK1, JAK2, JAK3, and TYK2) play an essential role in the receptor signaling of cytokines that have been implicated in the pathogenesis of severe asthma, and there is emerging interest in the development of small
Autor:
Lesley M. Devenish, Molebogeng R. Lekalakala-Mokaba, Justyna Wojno, Tom H. Boyles, Jeannette Wadula, Muhammad N. Rajabally, Joy Cleghorn, Khine Swe Swe Han, Briette du Toit, Warren Lowman, Ernst Fredericks, Karin Swart, Gary Reubenson, Liliwe Shuping, Chanelle Moore, Caroline Maluleka, Trusha Nana, Adrian Brink
Publikováno v:
Southern African Journal of Infectious Diseases, Vol 35, Iss 1, Pp e1-e26 (2020)
Southern African Journal of Infectious Diseases
Southern African Journal of Infectious Diseases
Clostridioides difficile infection (CDI) is a problem in both developed and developing countries and is a common hospital-acquired infection. This guideline provides evidence-based practical recommendations for South Africa and other developing count
Autor:
Jonathan D Lea, Robert J. Young, Duncan S. Holmes, Christopher P. Tinworth, Jonathan P. Hutchinson, Semra Kitchen, Justyna Wojno-Picon, Leng Nickels, Michelle Pemberton, Hester Sheehan, Justyna Korczynska, Margarete Neu, Jessica L. Schneck, Efstratios Stratikos, Despoina Koumantou, Iain Uings, Ted Cecconie, Alex Phillipou, Emma J. Jones, John Liddle, Paul Rowland
Publikováno v:
Journal of medicinal chemistry. 63(6)
ER aminopeptidase 1 (ERAP1) is an intracellular enzyme that generates antigenic peptides and is an emerging target for cancer immunotherapy and the control of autoimmunity. ERAP1 inhibitors described previously target the active site and are limited
Autor:
Ziyaad Valley-Omar, Gert Marais, Arash Iranzadeh, Michelle Naidoo, Stephen Korsman, Tongai Maponga, Hannah Hussey, Mary-Ann Davies, Andrew Boulle, Deelan Doolabh, Mariska Laubscher, Justyna Wojno, J.D. Deetlefs, Jean Maritz, Lesley Scott, Nokukhanya Msomi, Cherise Naicker, Houriiyah Tegally, Tulio de Oliveira, Jinal Bhiman, Carolyn Williamson, Wolfgang Preiser, Diana Hardie, Nei-yuan Hsiao
Publikováno v:
Journal of Virological Methods
Routine SARS-CoV-2 surveillance in the Western Cape region of South Africa (January-August 2021) found a reduced RT-PCR amplification efficiency of the RdRp-gene target of the Seegene, Allplex 2019-nCoV diagnostic assay from June 2021 when detecting
Autor:
Nicholas C. O. Tomkinson, D. Heulyn Jones, Anthony William James Cooper, James P. Tellam, Justyna Wojno-Picon, Stefano Bresciani
Publikováno v:
Synlett. 28:577-582
Methods for the preparation of symmetrical and non-symmetrical 2,7-disubstituted 9H-fluorene derivatives are described.
Autor:
Justyna Wojno, Nicholas C. O. Tomkinson, D. Heulyn Jones, Stefano Bresciani, Alan R. Kennedy, Anthony William James Cooper, James P. Tellam
Publikováno v:
Organic & Biomolecular Chemistry. 14:172-182
The isomers of dibenzylamino-1-methylcyclohexan-1-ol and dibenzylamino-1-trifluoromethylcyclohexan-1-ol have been prepared. The stereochemistry of these compounds was unequivocally assigned through a combination of NMR spectroscopy and single crystal
Autor:
Patricia L. Podolin, Justyna Wojno-Picon, Baoqiang Guo, Andrew S. I. Loudon, Ryan Vonslow, Ryan P. Trump, Daniel Grant, Andrew S. MacDonald, Yolanda Sanchez, Anthony William James Cooper, Marie Pariollaud, D. Heulyn Jones, Brian Bolognese, Nicholas C. O. Tomkinson, Thomas Hopwood, Stefano Bresciani, David W. Ray, William J. Zuercher, Nicola Begley, Timothy M. Willson, Sheila Brown, Toryn Poolman, James P. Tellam, Dion A. Daniels, Ben Saer, Julie E. Gibbs
Publikováno v:
Pariollaud, M, Gibbs, J, Hopwood, T, Brown, S, Begley, N, Vonslow, R, Poolman, T, Guo, B, Saer, B, Jones, D H, Tellam, J P, Bresciani, S, Tomkinson, N C, Wojno-Picon, J, Cooper, A W, Daniels, D A, Trump, R P, Grant, D, Zuercher, W, Willson, T M, MacDonald, A S, Bolognese, B, Podolin, P L, Sanchez, Y, Loudon, A S & Ray, D W 2018, ' Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation ', The Journal of clinical investigation, vol. 128, no. 6, pp. 2281-2296 . https://doi.org/10.1172/JCI93910
The Journal of Clinical Investigation
The Journal of Clinical Investigation
Recent studies reveal that airway epithelial cells are critical pulmonary circadian pacemaker cells, mediating rhythmic inflammatory responses. Using mouse models, we now identify the rhythmic circadian repressor REV-ERBα as essential to the mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b850d90e252cb0cef62edd168f157db
https://strathprints.strath.ac.uk/64982/1/Pariollaud_etal_JCI2018_Circadian_clock_component_REV_ERBa_controls_homeostatic_regulation.pdf
https://strathprints.strath.ac.uk/64982/1/Pariollaud_etal_JCI2018_Circadian_clock_component_REV_ERBa_controls_homeostatic_regulation.pdf
Autor:
Kevin R. Munro, Nicholas C. O. Tomkinson, Luke H. Chamberlain, Matthieu Riviere, Terry K. Smith, Jennifer Greaves, Justyna Wojno, Stuart C. Davidson
This work was funded by Biotechnology and Biological Sciences Research Council Grant BB/L022087/1 (to T.K.S., N.C.O.T., and L.H.C.) and Wellcome Trust Grant 093228 (to T.K.S.). S-acylation is a major posttranslational modification, catalyzed by the z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6d7d0c815805dc66f4895c2770014f
https://hdl.handle.net/10023/11394
https://hdl.handle.net/10023/11394
Autor:
Liam R. Cox, John-Paul Jukes, Dawn Shepherd, Hemza Ghadbane, Gurdyal S. Besra, Justyna Wojno, Vincenzo Cerundolo
Publikováno v:
ACS Chemical Biology
Invariant natural killer T (iNKT) cells are restricted by the non-polymorphic MHC class I-like protein, CD1d, and activated following presentation of lipid antigens bound to CD1d molecules. The prototypical iNKT cell agonist is α-galactosyl ceramide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d9a31879e81ce14df589c714d03951
https://doi.org/10.1021/cb2005017
https://doi.org/10.1021/cb2005017